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Slc20a1 Gene Detail
Summary
  • Symbol
    Slc20a1
  • Name
    solute carrier family 20, member 1
  • Synonyms
    Glvr1, Glvr-1, PiT-1
  • Feature Type
    protein coding gene
  • IDs
    MGI:108392
    NCBI Gene: 20515
  • Gene Overview
    MyGene.info: SLC20A1
Location & Maps
more
  • Sequence Map
    Chr2:129198764-129211616 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      12853 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 2, 62.79 cM
  • Mapping Data
    8 experiments
Homology
more
  • Human Ortholog
    SLC20A1, solute carrier family 20 member 1
  • Vertebrate Orthologs
    10
  • Human Ortholog
    SLC20A1, solute carrier family 20 member 1
    Orthology source: HGNC, HomoloGene
  • Synonyms
    Glvr-1, GLVR1, PiT-1, PIT1
  • Links
    NCBI Gene ID: 6574
    neXtProt AC: NX_Q8WUM9

  • Chr Location
    2q13; chr2:112645857-112663825 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    43 phenotypes from 5 alleles in 6 genetic backgrounds
    14 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    14
  • Chemically induced (other)
    1
  • Gene trapped
    6
  • Radiation induced
    1
  • Targeted
    6
  • Genomic Mutations
    2 involving Slc20a1
  • Incidental Mutations
Mice homozygous for a knock-out allele exhibit mid-gestation lethality associated with abnormal vitelline vasculature, growth retardation, and anemia.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000015425 VEGA Gene Model | MGI Sequence Detail 12853 C57BL/6J ±  kb
transcript OTTMUST00000036624 VEGA | MGI Sequence Detail 3219 Not Applicable  
polypeptide OTTMUSP00000016435 VEGA | MGI Sequence Detail 681 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    124 from dbSNP Build 142
  • RFLP
Protein
Information
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  • UniProt
    3 Sequences
  • Protein Ontology
    PR:000014979 sodium-dependent phosphate transporter 1
  • InterPro Domains
    IPR001204 Phosphate transporter
Molecular
Reagents
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  • All nucleic 23
    Genomic 2
    cDNA 18
    Primer pair 3

    Microarray probesets 5
Other
Accession IDs
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MGD-MRK-10163, MGD-MRK-10164, MGD-MRK-37434, MGI:2139020
References
more
  • Summaries
    All 51
    Developmental Gene Expression 6
    Gene Ontology 6
    Phenotypes 14
  • Earliest
    J:11031 Kaelbling M, et al., Localization of the human gene allowing infection by gibbon ape leukemia virus to human chromosome region 2q11-q14 and to the homologous region on mouse chromosome 2. J Virol. 1991 Apr;65(4):1743-7
  • Latest
    J:221058 Chavkin NW, et al., Phosphate uptake-independent signaling functions of the type III sodium-dependent phosphate transporter, PiT-1, in vascular smooth muscle cells. Exp Cell Res. 2015 Apr 10;333(1):39-48

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
07/12/2016
MGI 6.04
The Jackson Laboratory