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Sephs2 Gene Detail
Summary
  • Symbol
    Sephs2
  • Name
    selenophosphate synthetase 2
  • Synonyms
    Sps2, Ysg3
  • Feature Type
    protein coding gene
  • IDs
    MGI:108388
    NCBI Gene: 20768
  • Alliance
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:127271879-127274055 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 7, 69.43 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    32 from dbSNP Build 142
  • Strain Annotations
    18
  • RFLP
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_108388
protein coding gene Chr7:127271879-127274059 (-)
129S1/SvImJ MGP_129S1SvImJ_G0033030
protein coding gene Chr7:131613337-131615514 (-)
A/J MGP_AJ_G0033013
protein coding gene Chr7:128105813-128107988 (-)
AKR/J MGP_AKRJ_G0032945
protein coding gene Chr7:131359700-131361875 (-)
BALB/cJ MGP_BALBcJ_G0033018
protein coding gene Chr7:127772482-127774649 (-)
C3H/HeJ MGP_C3HHeJ_G0032728
protein coding gene Chr7:131297762-131299932 (-)
C57BL/6NJ MGP_C57BL6NJ_G0033524
protein coding gene Chr7:136723844-136726011 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0030496
protein coding gene Chr7:129315485-129317650 (-)
CAST/EiJ MGP_CASTEiJ_G0032057
protein coding gene Chr7:123090700-123092874 (-)
CBA/J MGP_CBAJ_G0032701
protein coding gene Chr7:141331561-141333776 (-)
DBA/2J MGP_DBA2J_G0032853
protein coding gene Chr7:126078529-126080696 (-)
FVB/NJ MGP_FVBNJ_G0032806
protein coding gene Chr7:125932476-125934646 (-)
LP/J MGP_LPJ_G0032947
protein coding gene Chr7:133072565-133074735 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0032838
protein coding gene Chr7:142467675-142469840 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0033543
protein coding gene Chr7:130377971-130380146 (-)
PWK/PhJ MGP_PWKPhJ_G0031765
protein coding gene Chr7:119088289-119090511 (-)
SPRET/EiJ MGP_SPRETEiJ_G0031610
protein coding gene Chr7:117215595-117217759 (-)
WSB/EiJ MGP_WSBEiJ_G0032169
protein coding gene Chr7:131345551-131347727 (-)



Homology
more
  • Human Ortholog
    SEPHS2, selenophosphate synthetase 2
  • Vertebrate Orthologs
    9
  • Human Ortholog
    SEPHS2, selenophosphate synthetase 2
    Orthology source: HomoloGene, HGNC
  • Synonyms
    SPS2
  • Links
    NCBI Gene ID: 22928
    neXtProt AC: NX_Q99611
    UniProt: Q99611

  • Chr Location
    16p11.2; chr16:30443625-30445975 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000049091 Ensembl Gene Model | MGI Sequence Detail 2177 C57BL/6J ±  kb
transcript ENSMUST00000082428 Ensembl | MGI Sequence Detail 2177 Not Applicable  
polypeptide ENSMUSP00000081009 Ensembl | MGI Sequence Detail 452 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 15
    cDNA 15

    Microarray probesets 5
Other
Accession IDs
less
MGD-MRK-28095, MGD-MRK-37428
References
more
  • Summaries
    All 31
    Developmental Gene Expression 5
    Gene Ontology 5
    Phenotypes 4
  • Earliest
    J:29278 Guimaraes MJ, et al., A new approach to the study of haematopoietic development in the yolk sac and embryoid bodies. Development. 1995 Oct;121(10):3335-46
  • Latest
    J:235561 Gladyshev VN, et al., Selenoprotein Gene Nomenclature. J Biol Chem. 2016 Nov 11;291(46):24036-24040

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
03/13/2019
MGI 6.13
The Jackson Laboratory