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Snrk Gene Detail
Summary
  • Symbol
    Snrk
  • Name
    SNF related kinase
  • Synonyms
    2010012F07Rik, MGC:28970, mKIAA0096, SNRK
  • Feature Type
    protein coding gene
  • IDs
    MGI:108104
    NCBI Gene: 20623
  • Alliance
    genome feature page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:121946332-121998768 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 9, 72.89 cM
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1232 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_108104
 protein coding gene Chr9:121946332-121998768 (+)
129S1/SvImJ ENSMUSG00200028476
 protein coding gene Chr9:119070992-119123423 (+)
A/J ENSMUSG00195027150
 protein coding gene Chr9:118233952-118286432 (+)
AKR/J ENSMUSG00220019018
 protein coding gene Chr9:118687794-118740183 (+)
BALB/cJ ENSMUSG00180028294
 protein coding gene Chr9:118771951-118824434 (+)
C3H/HeJ ENSMUSG00175018382
 protein coding gene Chr9:119010197-119062678 (+)
C57BL/6NJ ENSMUSG00215024021
 protein coding gene Chr9:118901004-118953440 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0032840
 protein coding gene Chr9:117483117-117536786 (+)
CAST/EiJ ENSTCUG00005016329
 protein coding gene Chr9:118618195-118667468 (+)
CBA/J ENSMUSG00210037926
 protein coding gene Chr9:118727494-118779887 (+)
DBA/2J ENSMUSG00185015066
 protein coding gene Chr9:119063153-119115544 (+)
FVB/NJ ENSMUSG00205018783
 protein coding gene Chr9:118900550-118953032 (+)
JF1/MsJ ENSUMUG00000035376
 protein coding gene Chr9:118881454-118933979 (+)
LP/J ENSMUSG00230037434
 protein coding gene Chr9:119213344-119265776 (+)
NOD/ShiLtJ ENSMUSG00190014980
 protein coding gene Chr9:118668470-118720900 (+)
NZO/HlLtJ ENSMUSG00225022521
 protein coding gene Chr9:119473724-119526160 (+)
PWK/PhJ ENSLUMG00010034954
 protein coding gene Chr9:118770024-118822608 (+)
SPRET/EiJ ENSMSPG00010022898
 protein coding gene Chr9:120485416-120539282 (+)
WSB/EiJ ENSIUOG00005019187
 protein coding gene Chr9:118094109-118146487 (+)



Homology
more
  • Human Ortholog
    SNRK, SNF related kinase
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SNRK, SNF related kinase
  • Synonyms
    HSNFRK
  • Links
    NCBI Gene ID: 54861
    UniProt: Q9NRH2

  • Chr Location
    3p22.1; chr3:43286510-43424764 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    37 phenotypes from 4 alleles in 5 genetic backgrounds
    15 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele exhibit neonatal lethality with enlarged left ventricle and altered lipid levels.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    33
  • GO References
    10
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    722
  • Tissues
    78
  • cDNA Data
    130
  • Literature Summary
    6
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 20623 NCBI Gene Model | MGI Sequence Detail 52437 C57BL/6J ±  kb
    transcript NM_001357774 RefSeq | MGI Sequence Detail 5058 C57BL/6  
    polypeptide Q8VDU5 UniProt | EBI | MGI Sequence Detail 748 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 137
      cDNA 131
      Primer pair 6
      Antibodies 3

      Microarray probesets 6
    Other
    Accession IDs
    less
    MGD-MRK-37141, MGI:1919310, MGI:2140107, MGI:2143051, MGI:2143318
    References
    more
    • Summaries
      All 64
      Developmental Gene Expression 6
      Gene Ontology 10
      Phenotypes 15
    • Earliest
      J:44483 Brady KP, et al., Genetic mapping of 262 loci derived from expressed sequences in a murine interspecific cross using single-strand conformational polymorphism analysis. Genome Res. 1997 Nov;7(11):1085-93
    • Latest
      J:374847 Yu CJ, et al., Smooth muscle cell (SMC)-Specific SNRK deletion in mouse causes congenital short bowel syndrome and premature death. Biochem Biophys Rep. 2025 Dec;44:102298
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/08/2026
    MGI 6.24     		The Jackson Laboratory