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Snrk Gene Detail
Summary
  • Symbol
    Snrk
  • Name
    SNF related kinase
  • Synonyms
    2010012F07Rik, MGC:28970, mKIAA0096, SNRK
  • Feature Type
    protein coding gene
  • IDs
    MGI:108104
    NCBI Gene: 20623
  • Gene Overview
    MyGene.info: SNRK
Location & Maps
more
  • Sequence Map
    Chr9:122117283-122169702 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      52420 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 9, 72.89 cM
  • Mapping Data
    4 experiments
Homology
more
  • Human Ortholog
    SNRK, SNF related kinase
  • Vertebrate Orthologs
    10
  • Human Ortholog
    SNRK, SNF related kinase
    Orthology source: HomoloGene, HGNC
  • Synonyms
    HSNFRK
  • Links
    NCBI Gene ID: 54861
    neXtProt AC: NX_Q9NRH2

  • Chr Location
    3p22.1; chr3:43286512-43351143 (+)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 9797
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: SNRK
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    12 phenotypes from 2 alleles in 3 genetic backgrounds
    3 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele exhibit neonatal lethality with enlarged left ventricle and altered lipid levels.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000027423 VEGA Gene Model | MGI Sequence Detail 52420 C57BL/6J ±  kb
transcript OTTMUST00000067849 VEGA | MGI Sequence Detail 4722 Not Applicable  
polypeptide OTTMUSP00000034202 VEGA | MGI Sequence Detail 748 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    167 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 131
    cDNA 129
    Primer pair 2

    Microarray probesets 6
Other
Accession IDs
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MGD-MRK-37141, MGI:1919310, MGI:2140107, MGI:2143051, MGI:2143318
References
more
  • Summaries
    All 40
    Developmental Gene Expression 6
    Gene Ontology 5
    Phenotypes 3
  • Earliest
    J:44483 Brady KP, et al., Genetic mapping of 262 loci derived from expressed sequences in a murine interspecific cross using single-strand conformational polymorphism analysis. Genome Res. 1997 Nov;7(11):1085-93
  • Latest
    J:218247 Cossette SM, et al., Sucrose non-fermenting related kinase enzyme is essential for cardiac metabolism. Biol Open. 2014;4(1):48-61

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
11/29/2016
MGI 6.06
The Jackson Laboratory