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Frrs1
Gene Detail
Symbol

Name
ID
Frrs1
ferric-chelate reductase 1
MGI:108076
Synonyms
Sdfr2
Feature Type
protein coding gene
Genetic Map
Chromosome 3
50.49 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr3:116859464-116908177 bp, + strand
From VEGA annotation of GRCm38

  48714 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:40653  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 2 zebrafish

HCOP human homology predictions: FRRS1
Gene Tree: Frrs1

Human
homologs
FRRS1, ferric-chelate reductase 1
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 391059
neXtProt AC: NX_Q6ZNA5

Human Synonyms: SDFR2, SDR2

Human Chr (Location): 1p21.2; chr1:99708632-99766630 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(25) : Gene trapped(23) Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Frrs1 interacts with 99 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (13 annotations)
Process oxidation-reduction process, transport
Component integral component of membrane, membrane
Function epoxyqueuosine reductase activity, ferric-chelate reductase activity, ...
External Resources: FuncBase
Expression
Literature Summary: (1 records)
Data Summary: Results (22)    Tissues (3)    Images (22)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 22
cDNA source data(81)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase LOC100497064    NEW 
Molecular
reagents
All nucleic(81) cDNA(81)
Microarray probesets(3)
Other database
links
VEGA Gene Model OTTMUSG00000054477 (Evidence)
Ensembl Gene Model ENSMUSG00000033386 (Evidence)
Entrez Gene 20321 (Evidence)
UniGene 66293
DFCI TC1578675
DoTS DT.111060123, DT.40172258, DT.87068814
NIA Mouse Gene Index U003778
EC 1.-.-.-
Consensus CDS Project CCDS17792.1
International Mouse Phenotyping Consortium Status Frrs1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000054477 VEGA Gene Model | MGI Sequence Detail 48714 C57BL/6J ±  kb
transcript OTTMUST00000135306 VEGA | MGI Sequence Detail 2377 Not Applicable 
polypeptide OTTMUSP00000071627 VEGA | MGI Sequence Detail 592 Not Applicable 

For the selected sequences
All sequences(48) RefSeq(10) UniProt(4)
Polymorphisms
SNPs within 2kb(500 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR006593 Cytochrome b561/ferric reductase transmembrane
InterPro IPR005018 DOMON domain
InterPro IPR002861 Reeler domain
Protein Ontology PR:000007669 ferric-chelate reductase 1
References
(Earliest) J:36732 Shirozu M, et al., Characterization of novel secreted and membrane proteins isolated by the signal sequence trap method. Genomics. 1996 Nov 1;37(3):273-80
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(33)
Other
accession IDs
MGD-MRK-37113, MGI:2139633

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/25/2015
MGI 6.0
The Jackson Laboratory