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Frrs1
Gene Detail
Symbol

Name
ID
Frrs1
ferric-chelate reductase 1
MGI:108076
Synonyms
Sdfr2
Feature Type
protein coding gene
Genetic Map
Chromosome 3
50.49 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr3:116878227-116903750 bp, + strand
From Ensembl annotation of GRCm38

  25524 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:40653  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 2 zebrafish

Gene Tree: Frrs1

Human
homologs
Human Homolog FRRS1, ferric-chelate reductase 1
NCBI Gene ID 391059
neXtProt AC  NX_Q6ZNA5
Human Synonyms  SDFR2, SDR2
Human Chr (Location)  1p21.2; chr1:99708650-99766630 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(25) : Gene trapped(23) Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Frrs1 interacts with 99 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (13 annotations)
Process oxidation-reduction process, transport
Component integral component of membrane, membrane
Function epoxyqueuosine reductase activity, ferric-chelate reductase activity, ...
External Resources: FuncBase
Expression
Literature Summary: (1 records)
Data Summary: Results (22)    Tissues (3)    Images (22)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 22
cDNA source data(81)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(81) cDNA(81)
Microarray probesets(3)
Other database
links
Ensembl Gene ModelENSMUSG00000033386 (Evidence)
Entrez Gene20321 (Evidence)
UniGene66293
DFCITC1578675
DoTSDT.111060123, DT.40172258, DT.87068814
NIA Mouse Gene IndexU003778
EC1.-.-.-
Consensus CDS ProjectCCDS17792.1
International Mouse Knockout Project StatusFrrs1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000033386 Ensembl Gene Model | MGI Sequence Detail 25524 C57BL/6J ±  kb
transcript ENSMUST00000040260 Ensembl | MGI Sequence Detail 2396 Not Applicable 
polypeptide ENSMUSP00000039487 Ensembl | MGI Sequence Detail 592 Not Applicable 

For the selected sequences
All sequences(32) RefSeq(8) UniProt(1)
Polymorphisms
SNPs within 2kb(434 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR006593 Cytochrome b561/ferric reductase transmembrane
InterPro IPR005018 DOMON domain
InterPro IPR002861 Reeler domain
Protein Ontology PR:000007669 ferric-chelate reductase 1
References
(Earliest) J:36732 Shirozu M, et al., Characterization of novel secreted and membrane proteins isolated by the signal sequence trap method. Genomics. 1996 Nov 1;37(3):273-80
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(32)
Other
accession IDs
MGD-MRK-37113, MGI:2139633

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
10/08/2014
MGI 5.20
The Jackson Laboratory