About   Help   FAQ
Rit2
Gene Detail
Symbol

Name
ID
Rit2
Ras-like without CAAX 2
MGI:108054
Synonyms
Rin, Roc2
Feature Type
protein coding gene
Genetic Map
Chromosome 18
17.69 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr18:30973489-31317290 bp, - strand
From VEGA annotation of GRCm38

  343802 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:2198  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 rhesus macaque; 1 dog; 1 chicken

Protein SuperFamily: ras protein
Gene Tree: Rit2

Human
homologs
Human Homolog RIT2, Ras-like without CAAX 2
NCBI Gene ID 6014
neXtProt AC  NX_Q99578
Human Synonyms  RIBA, RIN, ROC2
Human Chr (Location)  18q12.3; chr18:42743218-43115692 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(6) : Gene trapped(5) Targeted(1)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Rit2 interacts with 242 markers (Mir1a-1, Mir1a-2, Mir7-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (12 annotations)
Process GTP catabolic process, signal transduction, ...
Component membrane, nucleus, ...
Function calmodulin binding, GTP binding, ...
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (156)    Tissues (14)    Images (22)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 156
cDNA source data(36)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(37) cDNA(37)
Microarray probesets(9)
Other database
links
VEGA Gene ModelOTTMUSG00000033066 (Evidence)
Ensembl Gene ModelENSMUSG00000057455 (Evidence)
Entrez Gene19762 (Evidence)
UniGene5163
DFCITC1615181, TC1575495
DoTSDT.60110528, DT.94246176, DT.91563091, DT.87034117
NIA Mouse Gene IndexU038274
Consensus CDS ProjectCCDS29108.1
International Mouse Knockout Project StatusRit2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000033066 VEGA Gene Model | MGI Sequence Detail 343802 C57BL/6J ±  kb
transcript OTTMUST00000082578 VEGA | MGI Sequence Detail 1806 Not Applicable 
polypeptide OTTMUSP00000044275 VEGA | MGI Sequence Detail 217 Not Applicable 

For the selected sequences
All sequences(48) RefSeq(2) UniProt(5)
Polymorphisms
SNPs within 2kb(2654 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR027417 P-loop containing nucleoside triphosphate hydrolase
InterPro IPR001806 Small GTPase superfamily
InterPro IPR020849 Small GTPase superfamily, Ras type
InterPro IPR005225 Small GTP-binding protein domain
Protein Ontology PR:000014029 GTP-binding protein Rit2
References
(Earliest) J:36057 Lee CHJ, et al., Rin, a neuron-specific and calmodulin-binding small G-protein, and Rit define a novel subfamily of ras proteins. J Neurosci. 1996 Nov 1;16(21):6784-94
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(37)
Other
accession IDs
MGD-MRK-37090, MGI:1931467

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
11/18/2014
MGI 5.20
The Jackson Laboratory