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Smyd5 Gene Detail
Summary
  • Symbol
    Smyd5
  • Name
    SET and MYND domain containing 5
  • Synonyms
    MGC:29044, NN8-4AG, Rai15, Rrg1
  • Feature Type
    protein coding gene
  • IDs
    MGI:108048
    NCBI Gene: 232187
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr6:85431989-85446435 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 6, 37.44 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    33 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_108048
protein coding gene Chr6:85431976-85446435 (+)
129S1/SvImJ MGP_129S1SvImJ_G0030953
protein coding gene Chr6:86598592-86613055 (+)
A/J MGP_AJ_G0030922
protein coding gene Chr6:83300536-83315133 (+)
AKR/J MGP_AKRJ_G0030850
protein coding gene Chr6:85712645-85728446 (+)
BALB/cJ MGP_BALBcJ_G0030932
protein coding gene Chr6:83292605-83307738 (+)
C3H/HeJ MGP_C3HHeJ_G0030778
protein coding gene Chr6:98718092-98732504 (-)
C57BL/6NJ MGP_C57BL6NJ_G0031392
protein coding gene Chr6:88983091-88997529 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0028577
protein coding gene Chr6:81574116-81588700 (+)
CAST/EiJ MGP_CASTEiJ_G0030041
protein coding gene Chr6:85727494-85743224 (+)
CBA/J MGP_CBAJ_G0030619
protein coding gene Chr6:92472213-92486638 (+)
DBA/2J MGP_DBA2J_G0030772
protein coding gene Chr6:82583563-82598305 (+)
FVB/NJ MGP_FVBNJ_G0030725
protein coding gene Chr6:81785908-81800442 (+)
LP/J MGP_LPJ_G0030851
protein coding gene Chr6:86594193-86608836 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0030761
protein coding gene Chr6:96676880-96691308 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0031416
protein coding gene Chr6:85514701-85529150 (+)
PWK/PhJ MGP_PWKPhJ_G0029756
protein coding gene Chr6:81518904-81533548 (+)
SPRET/EiJ MGP_SPRETEiJ_G0029584
protein coding gene Chr6:84370904-84387241 (+)
WSB/EiJ MGP_WSBEiJ_G0030122
protein coding gene Chr6:85960363-85976052 (+)



Homology
more
  • Human Ortholog
    SMYD5, SMYD family member 5
  • Vertebrate Orthologs
    10
  • Human Ortholog
    SMYD5, SMYD family member 5
    Orthology source: HomoloGene, HGNC
  • Synonyms
    NN8-4AG, RAI15, RRG1, ZMYND23
  • Links
    NCBI Gene ID: 10322
    neXtProt AC: NX_Q6GMV2
    UniProt: Q6GMV2

  • Chr Location
    2p13.2; chr2:73214238-73227227 (+)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 6143
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: SMYD5
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    11 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000033706 Ensembl Gene Model | MGI Sequence Detail 14447 C57BL/6J ±  kb
transcript ENSMUST00000045693 Ensembl | MGI Sequence Detail 2486 Not Applicable  
polypeptide ENSMUSP00000048537 Ensembl | MGI Sequence Detail 416 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 117
    Genomic 2
    cDNA 115

    Microarray probesets 7
Other
Accession IDs
less
MGD-MRK-37084, MGI:2141690
References
more
  • Summaries
    All 38
    Developmental Gene Expression 2
    Gene Ontology 1
    Phenotypes 11
  • Earliest
    J:34386 Shago M, et al., Isolation of a novel retinoic acid-responsive gene by selection of genomic fragments derived from CpG-island-enriched DNA. Mol Cell Biol. 1996 Aug;16(8):4337-48
  • Latest
    J:243553 Fisher CL, et al., An efficient method for generation of bi-allelic null mutant mouse embryonic stem cells and its application for investigating epigenetic modifiers. Nucleic Acids Res. 2017 Dec 1;45(21):e174

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
03/13/2019
MGI 6.13
The Jackson Laboratory