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Smyd5 Gene Detail
Summary
  • Symbol
    Smyd5
  • Name
    SET and MYND domain containing 5
  • Synonyms
    MGC:29044, NN8-4AG, Rai15, Rrg1
  • Feature Type
    protein coding gene
  • IDs
    MGI:108048
    NCBI Gene: 232187
Location & Maps
more
  • Sequence Map
    Chr6:85431989-85446435 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      14447 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 6, 37.44 cM
  • Mapping Data
    3 experiments
Homology
more
  • Human Ortholog
    SMYD5, SMYD family member 5
  • Vertebrate Orthologs
    10
  • Human Ortholog
    SMYD5, SMYD family member 5
    Orthology source: HomoloGene, HGNC
  • Synonyms
    NN8-4AG, RAI15, RRG1, ZMYND23
  • Links
    NCBI Gene ID: 10322
    neXtProt AC: NX_Q6GMV2

  • Chr Location
    2p13.2; chr2:73214238-73227227 (+)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 6143
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: SMYD5
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    2 phenotypes from 1 allele in 2 genetic backgrounds
    11 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    24
  • Gene trapped
    21
  • Spontaneous
    1
  • Targeted
    2
  • Genomic Mutations
    1 involving Smyd5
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000017438 VEGA Gene Model | MGI Sequence Detail 14447 C57BL/6J ±  kb
transcript OTTMUST00000042294 VEGA | MGI Sequence Detail 2486 Not Applicable  
polypeptide OTTMUSP00000019005 VEGA | MGI Sequence Detail 416 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    33 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 115
    Genomic 2
    cDNA 113

    Microarray probesets 7
Other
Accession IDs
less
MGD-MRK-37084, MGI:2141690
References
more
  • Summaries
    All 36
    Developmental Gene Expression 2
    Gene Ontology 1
    Phenotypes 11
  • Earliest
    J:34386 Shago M, et al., Isolation of a novel retinoic acid-responsive gene by selection of genomic fragments derived from CpG-island-enriched DNA. Mol Cell Biol. 1996 Aug;16(8):4337-48
  • Latest
    J:201630 Ryder E, et al., Molecular characterization of mutant mouse strains generated from the EUCOMM/KOMP-CSD ES cell resource. Mamm Genome. 2013 Aug;24(7-8):286-94

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/22/2016
MGI 6.06
The Jackson Laboratory