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Ccna1
Gene Detail
 Symbol
Name
ID
Ccna1
cyclin A1
MGI:108042
Feature Type protein coding gene
Genetic Map
Chromosome 3
26.52 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr3:55045469-55055055 bp, - strand
From NCBI annotation of GRCm38

  9587 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:31203  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Protein SuperFamily: cyclin, A/B/D/E types
Gene Tree: Ccna1

Human
homologs
Human Homolog CCNA1, cyclin A1
NCBI Gene ID 8900
neXtProt AC  NX_P78396
Human Synonyms  CT146
Human Chr (Location)  13q12.3-q13; chr13:36431830-36442882 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(6) : Targeted(6)
Incidental mutations (data from Mutagenetix , APF )
 
Homozygous null males are infertile due to the arrest of spermatogenesis prior to the first meiotic division. Female mutant mice are fertile.
 
Interactions
Ccna1 interacts with 30 markers (Mir24-1, Mir24-2, Mir93, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (18 annotations)
Process cell cycle, cell differentiation, ...
Component cytoplasm, cytoskeleton, ...
Function protein binding, protein kinase binding
External Resources: FuncBase
Expression
Literature Summary: (32 records)
Data Summary: Results (51)    Tissues (7)   
Theiler Stages: 2, 3, 4, 21, 24, 26, 28
Assay TypeResults
Immunohistochemistry 2
Western blot 13
RT-PCR 36
cDNA source data(7)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(9) Genomic(1) cDNA(7) Primer pair(1)
Microarray probesets(3)
Other database
links
Ensembl Gene ModelENSMUSG00000027793 (Evidence)
Entrez Gene12427 (Evidence)
UniGene4815
DFCITC1586658
DoTSDT.101712640, DT.60105227, DT.91352015
NIA Mouse Gene IndexU024057
Consensus CDS ProjectCCDS17356.1
International Mouse Knockout Project StatusCcna1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 12427 NCBI Gene Model | MGI Sequence Detail 9587 C57BL/6J ±  kb
transcript NM_007628 RefSeq | MGI Sequence Detail 1581 C57BL/6 
polypeptide Q61456 UniProt | EBI | MGI Sequence Detail 421 Not Applicable 

For the selected sequences
All sequences(34) RefSeq(18) UniProt(1)
Polymorphisms SNPs within 2kb(217 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR014400 Cyclin A/B/D/E
InterPro IPR015453 Cyclin A, G2/mitotic-specific
InterPro IPR004367 Cyclin, C-terminal domain
InterPro IPR013763 Cyclin-like
InterPro IPR006671 Cyclin, N-terminal
Protein Ontology PR:000005114 cyclin-A1
Graphical View of Protein Domain Structure
References (Earliest) J:30821 Sweeney C, et al., A distinct cyclin A is expressed in germ cells in the mouse. Development. 1996 Jan;122(1):53-64
(Latest) J:205333 Otero JJ, et al., Cerebellar cortical lamination and foliation require cyclin A2. Dev Biol. 2014 Jan 15;385(2):328-39
All references(73)
Other
accession IDs
MGD-MRK-37078

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/19/2014
MGI 5.19
The Jackson Laboratory