Cited1
Gene Detail

Symbol

Name
ID

Cited1
Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 1
MGI:108023

Synonyms

Msg1

Feature Type

protein coding gene

Genetic Map

Chromosome X
45.25 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)

Sequence Map

ChrX:102247381-102252181 bp, - strand From VEGA annotation of GRCm38   4801 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate
homology

HomoloGene:3057  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 western clawed frog; 1 zebrafish

Gene Tree: Cited1

Human
homologs

Human Homolog		CITED1, Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1
NCBI Gene ID		4435
neXtProt AC		NX_Q99966
Human Synonyms		MSG1
Human Chr (Location)		Xq13.1; chrX:72301638-72307187 (-)  GRCh38

Mutations,
alleles, and
phenotypes

All mutations/alleles(3) : Targeted(3)
 

Mutation of this locus results in impaired embyronic growth and survival due to defects in trophoblast and placental development. Phenotypic penetrance is subject to influence by genetic background and parental inheritance.

 

Interactions

Cited1 interacts with 9 markers (Mir17, Mir20b, Mir106a, ...)

View All

Gene Ontology
(GO)
classifications

All GO classifications: (63 annotations)

Process	apoptotic process, cell differentiation, ...
Component	cytoplasm, cytosol, ...
Function	chromatin binding, co-SMAD binding, ...

External Resources: FuncBase

Expression

Literature Summary: (56 records)

Data Summary: Results (427)    Tissues (198)    Images (87)    Tissue x Stage Matrix (view)

Assay Type	Results
Immunohistochemistry	28
RNA in situ	348
In situ reporter (knock in)	22
Northern blot	3
Western blot	12
RT-PCR	14

cDNA source data(57)
External Resources: Allen Institute   GENSAT   GEO   Expression Atlas

Molecular
reagents

All nucleic(66) Genomic(2) cDNA(57) Primer pair(4) Other(3)
Microarray probesets(3)

Other database
links

VEGA Gene Model	OTTMUSG00000018307 (Evidence)
Ensembl Gene Model	ENSMUSG00000051159 (Evidence)
Entrez Gene	12705 (Evidence)
UniGene	2390
DFCI	TC1591415, TC1580323
DoTS	DT.111023812, DT.494818, DT.94180232
NIA Mouse Gene Index	U039587
Consensus CDS Project	CCDS30322.1
International Mouse Knockout Project Status	Cited1

Sequences

Length	Strain/Species
genomic	OTTMUSG00000018307	VEGA Gene Model | MGI Sequence Detail	4801	C57BL/6J
transcript	OTTMUST00000044231	VEGA | MGI Sequence Detail	901	Not Applicable
polypeptide	OTTMUSP00000019880	VEGA | MGI Sequence Detail	203	Not Applicable

All sequences(50) RefSeq(8) UniProt(5)

Polymorphisms

PCR(1) : SNPs within 2kb(0 from dbSNP Build 137)

Protein-related
information

Resource	ID	Description
InterPro	IPR007576	CITED
Protein Ontology	PR:000005505	Cbp/p300-interacting transactivator 1

References

(Earliest) J:36248 Shioda T, et al., msg1, a novel melanocyte-specific gene, encodes a nuclear protein and is associated with pigmentation. Proc Natl Acad Sci U S A. 1996 Oct 29;93(22):12298-303
(Latest) J:214666 Brunskill EW, et al., A gene expression atlas of early craniofacial development. Dev Biol. 2014 Jul 15;391(2):133-46
All references(101)

Other
accession IDs

MGD-MRK-37059, MGI:2147868, MGI:2147960