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Cited1 Gene Detail
Summary
  • Symbol
    Cited1
  • Name
    Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 1
  • Synonyms
    Msg1
  • Feature Type
    protein coding gene
  • IDs
    MGI:108023
    NCBI Gene: 12705
  • Gene Overview
    MyGene.info: CITED1
Location & Maps
more
  • Sequence Map
    ChrX:102247381-102252181 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      4801 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome X, 45.25 cM
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    CITED1, Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 1
  • Vertebrate Orthologs
    9
  • Human Ortholog
    CITED1, Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 1
    Orthology source: HGNC, HomoloGene
  • Synonyms
    MSG1
  • Links
    NCBI Gene ID: 4435
    neXtProt AC: NX_Q99966

  • Chr Location
    Xq13.1; chrX:72301638-72307187 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    14 phenotypes from 2 alleles in 3 genetic backgrounds
    2 phenotypes from multigenic genotypes
    11 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    3
  • Targeted
    3
Mutation of this locus results in impaired embyronic growth and survival due to defects in trophoblast and placental development. Phenotypic penetrance is subject to influence by genetic background and parental inheritance.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000018307 VEGA Gene Model | MGI Sequence Detail 4801 C57BL/6J ±  kb
transcript OTTMUST00000044231 VEGA | MGI Sequence Detail 901 Not Applicable  
polypeptide OTTMUSP00000019880 VEGA | MGI Sequence Detail 203 Not Applicable  
For the selected sequence
Polymorphisms
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  • PCR
Protein
Information
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  • UniProt
    5 Sequences
  • Protein Ontology
    PR:000005505 Cbp/p300-interacting transactivator 1
  • InterPro Domains
    IPR007576 CITED
Molecular
Reagents
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  • All nucleic 67
    Genomic 2
    cDNA 57
    Primer pair 4
    Other 4

    Microarray probesets 3
Other
Accession IDs
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MGD-MRK-37059, MGI:2147868, MGI:2147960
References
more
  • Summaries
    All 102
    Developmental Gene Expression 60
    Gene Ontology 15
    Phenotypes 11
  • Earliest
    J:36248 Shioda T, et al., msg1, a novel melanocyte-specific gene, encodes a nuclear protein and is associated with pigmentation. Proc Natl Acad Sci U S A. 1996 Oct 29;93(22):12298-303
  • Latest
    J:228872 Song R, et al., Prorenin receptor is critical for nephron progenitors. Dev Biol. 2016 Jan 15;409(2):382-91

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/23/2016
MGI 6.05
The Jackson Laboratory