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Cited1 Gene Detail
Summary
  • Symbol
    Cited1
  • Name
    Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 1
  • Synonyms
    Msg1
  • Feature Type
    protein coding gene
  • IDs
    MGI:108023
    NCBI Gene: 12705
  • Gene Overview
    MyGene.info: CITED1
  • Alliance
    gene page
Location & Maps
more
  • Sequence Map
    ChrX:102247381-102252181 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser
  • Download
    Sequence
      4801 bp   ±  kb flank

  • Genome Browsers
    VEGA | Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome X, 45.25 cM
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    CITED1, Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 1
  • Vertebrate Orthologs
    9
  • Human Ortholog
    CITED1, Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    MSG1
  • Links
    NCBI Gene ID: 4435
    neXtProt AC: NX_Q99966
    UniProt: Q99966

  • Chr Location
    Xq13.1; chrX:72301638-72307187 (-)  GRCh38.p7
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    14 phenotypes from 2 alleles in 3 genetic backgrounds
    2 phenotypes from multigenic genotypes
    12 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mutation of this locus results in impaired embyronic growth and survival due to defects in trophoblast and placental development. Phenotypic penetrance is subject to influence by genetic background and parental inheritance.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    67
  • GO References
    15
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    431
  • Tissues
    199
  • cDNA Data
    57
  • Literature Summary
    66
  • Comparison Matrix
    Gene Expression + Phenotype
    • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic OTTMUSG00000018307 VEGA Gene Model | MGI Sequence Detail 4801 C57BL/6J ±  kb
    transcript OTTMUST00000044232 VEGA | MGI Sequence Detail 1090 Not Applicable  
    polypeptide OTTMUSP00000019881 VEGA | MGI Sequence Detail 203 Not Applicable  
    For the selected sequence
    Polymorphisms
    less
    • PCR
      1
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 67
      Genomic 2
      cDNA 57
      Primer pair 4
      Other 4

      Microarray probesets 3
    Other
    Accession IDs
    less
    MGD-MRK-37059, MGI:2147868, MGI:2147960
    References
    more
    • Summaries
      All 111
      Developmental Gene Expression 66
      Gene Ontology 15
      Phenotypes 12
    • Earliest
      J:36248 Shioda T, et al., msg1, a novel melanocyte-specific gene, encodes a nuclear protein and is associated with pigmentation. Proc Natl Acad Sci U S A. 1996 Oct 29;93(22):12298-303
    • Latest
      J:248185 Pan X, et al., Myc cooperates with beta-catenin to drive gene expression in nephron progenitor cells. Development. 2017 Nov 15;144(22):4173-4182
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    05/08/2018
    MGI 6.12     		The Jackson Laboratory