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Cited1
Gene Detail
Symbol

Name
ID
Cited1
Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 1
MGI:108023
Synonyms
Msg1
Feature Type
protein coding gene
Genetic Map
Chromosome X
45.25 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
ChrX:102247381-102252181 bp, - strand
From VEGA annotation of GRCm38

  4801 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:3057  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: CITED1
Gene Tree: Cited1

Human
homologs
CITED1, Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1
Orthology source: HomoloGene, HGNC

IDs:
NCBI Gene ID: 4435
neXtProt AC: NX_Q99966

Human Synonyms: MSG1

Human Chr (Location): Xq13.1; chrX:72301638-72307187 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(3) : Targeted(3)
 
Mutation of this locus results in impaired embyronic growth and survival due to defects in trophoblast and placental development. Phenotypic penetrance is subject to influence by genetic background and parental inheritance.
 
Interactions
Cited1 interacts with 9 markers (Mir17, Mir20b, Mir106a, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (63 annotations)
Process apoptotic process, cell differentiation, ...
Component cytoplasm, cytosol, ...
Function chromatin binding, co-SMAD binding, ...
External Resources: FuncBase
Expression
Literature Summary: (58 records)
Data Summary: Results (427)    Tissues (198)    Images (87)    Tissue x Stage Matrix (view)
Assay TypeResults
Immunohistochemistry 28
RNA in situ 348
In situ reporter (knock in) 22
Northern blot 3
Western blot 12
RT-PCR 14
cDNA source data(57)
Other mouse links: Allen Institute   GENSAT   GEO   Expression Atlas
Molecular
reagents
All nucleic(66) Genomic(2) cDNA(57) Primer pair(4) Other(3)
Microarray probesets(3)
Other database
links
VEGA Gene Model OTTMUSG00000018307 (Evidence)
Ensembl Gene Model ENSMUSG00000051159 (Evidence)
Entrez Gene 12705 (Evidence)
UniGene 2390
DFCI TC1591415, TC1580323
DoTS DT.111023812, DT.494818, DT.94180232
NIA Mouse Gene Index U039587
Consensus CDS Project CCDS30322.1
International Mouse Phenotyping Consortium Status Cited1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000018307 VEGA Gene Model | MGI Sequence Detail 4801 C57BL/6J ±  kb
transcript OTTMUST00000044231 VEGA | MGI Sequence Detail 901 Not Applicable 
polypeptide OTTMUSP00000019880 VEGA | MGI Sequence Detail 203 Not Applicable 

For the selected sequences
All sequences(51) RefSeq(8) UniProt(5)
Polymorphisms
PCR(1) : SNPs within 2kb(0 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR007576 CITED
Protein Ontology PR:000005505 Cbp/p300-interacting transactivator 1
References
(Earliest) J:36248 Shioda T, et al., msg1, a novel melanocyte-specific gene, encodes a nuclear protein and is associated with pigmentation. Proc Natl Acad Sci U S A. 1996 Oct 29;93(22):12298-303
(Latest) J:221164 Di Giovanni V, et al., Fibroblast growth factor receptor-Frs2alpha signaling is critical for nephron progenitors. Dev Biol. 2015 Apr 1;400(1):82-93
All references(101)
Other
accession IDs
MGD-MRK-37059, MGI:2147868, MGI:2147960

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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Funding Information
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last database update
06/23/2015
MGI 5.22
The Jackson Laboratory