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Sebox Gene Detail
Summary
  • Symbol
    Sebox
  • Name
    SEBOX homeobox
  • Synonyms
    OG9, Og9x
  • Feature Type
    protein coding gene
  • IDs
    MGI:108012
    NCBI Gene: 18292
  • Gene Overview
    MyGene.info: SEBOX
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:78503513-78505081 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 11, 46.74 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    12 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_108012
protein coding gene Chr11:78503447-78505081 (.)
129S1/SvImJ MGP_129S1SvImJ_G0018783
protein coding gene Chr11:79523419-79525053 (+)
A/J MGP_AJ_G0018749
protein coding gene Chr11:76474535-76476169 (+)
AKR/J MGP_AKRJ_G0018719
protein coding gene Chr11:78778197-78779831 (+)
BALB/cJ MGP_BALBcJ_G0018723
protein coding gene Chr11:76877645-76879279 (+)
C3H/HeJ MGP_C3HHeJ_G0018536
protein coding gene Chr11:78825143-78826777 (+)
C57BL/6NJ MGP_C57BL6NJ_G0019174
protein coding gene Chr11:81990720-81992354 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0016809
protein coding gene Chr11:73444693-73446302 (+)
CAST/EiJ MGP_CASTEiJ_G0018090
protein coding gene Chr11:79281875-79283504 (+)
CBA/J MGP_CBAJ_G0018507
protein coding gene Chr11:85600717-85602351 (+)
DBA/2J MGP_DBA2J_G0018615
protein coding gene Chr11:76049214-76050848 (+)
FVB/NJ MGP_FVBNJ_G0018605
protein coding gene Chr11:75639708-75641342 (+)
LP/J MGP_LPJ_G0018686
protein coding gene Chr11:80036819-80038453 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0018631
protein coding gene Chr11:85961937-85963571 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0019214
protein coding gene Chr11:79027012-79028646 (+)
PWK/PhJ MGP_PWKPhJ_G0017861
protein coding gene Chr11:76845635-76847267 (+)
SPRET/EiJ MGP_SPRETEiJ_G0017652
protein coding gene Chr11:78642651-78644282 (+)
WSB/EiJ MGP_WSBEiJ_G0018143
protein coding gene Chr11:78856348-78857982 (+)



Homology
more
  • Human Ortholog
    SEBOX, SEBOX homeobox
  • Vertebrate Orthologs
    7
  • Human Ortholog
    SEBOX, SEBOX homeobox
    Orthology source: HomoloGene, HGNC
  • Synonyms
    OG9, OG-9, OG9X
  • Links
    NCBI Gene ID: 645832
    UniProt: Q9HB31

  • Chr Location
    17q11.2; chr17:28364268-28365151 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    11 phenotype references
Adult mice homozygous for a targeted disruption of this gene display normal retinal morphology as well as normal electroretinograms under scotopic and photopic conditions.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 18292 NCBI Gene Model | MGI Sequence Detail 1569 C57BL/6J ±  kb
transcript NM_008759 RefSeq | MGI Sequence Detail 1347 Not Specified  
polypeptide P70368 UniProt | EBI | MGI Sequence Detail 190 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    2 Sequences
  • InterPro Domains
    IPR001356 Homeobox domain
    IPR009057 Homeobox-like domain superfamily
Molecular
Reagents
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  • All nucleic 20
    Genomic 1
    cDNA 15
    Primer pair 2
    Other 2

    Microarray probesets 4
Other
Accession IDs
less
MGD-MRK-37046
References
more
  • Summaries
    All 46
    Developmental Gene Expression 11
    Gene Ontology 6
    Phenotypes 11
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:249145 Goetz JJ, et al., Polo-Like Kinase 3 Appears Dispensable for Normal Retinal Development Despite Robust Embryonic Expression. PLoS One. 2016;11(3):e0150878

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/13/2018
MGI 6.13
The Jackson Laboratory