Kcnj9
Gene Detail

Symbol Name ID

Kcnj9 potassium inwardly-rectifying channel, subfamily J, member 9 MGI:108007

Synonyms

1700085N21Rik, Girk3, Kir3.3

Feature Type

protein coding gene

Genetic Map

Chromosome 1

79.66 cM
Detailed Genetic Map ± 1 cM


Mapping data(12)

Sequence Map

Chr1:172321033-172329263 bp, - strand From NCBI annotation of GRCm38   8231 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:37989  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 zebrafish

Protein SuperFamily: G protein-activated inward rectifier potassium channel
Gene Tree: Kcnj9

Human homologs

Human Homolog		KCNJ9, potassium inwardly-rectifying channel, subfamily J, member 9
NCBI Gene ID		3765
neXtProt AC		NX_Q92806
Human Synonyms		GIRK3, KIR3.3
Human Chr (Location)		1q23.2; chr1:160051360-160059212 (+)  GRCh37.p10

Alleles and phenotypes

All alleles(3) : Targeted(3)
 

Inactivation of this locus does not result in any overt phenotype.

 

Gene Ontology (GO) classifications

All GO classifications: (14 annotations)

Process	ion transport, potassium ion transport, ...
Component	integral to membrane, membrane, ...
Function	G-protein activated inward rectifier potassium channel activity, inward rectifier potassium channel activity, ...

External Resources: FuncBase

Expression

Literature Summary: (7 records)
Data Summary: Results (91)    Tissues (76)    Images (9)
Theiler Stages: 13, 15, 17, 19, 22, 23, 25, 28

Assay Type	Results
RNA in situ	35
RT-PCR	56

cDNA source data(18)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(47) Genomic(23) cDNA(19) Primer pair(5)
Microarray probesets(9)

Other database links

Ensembl Gene Model	ENSMUSG00000038026 (Evidence)
Entrez Gene	16524 (Evidence)
UniGene	261168
DFCI	TC1581217, TC1599511
DoTS	DT.40180403, DT.60100474, DT.99841618
NIA Mouse Gene Index	U022070
Consensus CDS Project	CCDS35783.1
International Mouse Knockout Project Status	Kcnj9

Sequences

Length	Strain/Species
genomic	16524	NCBI Gene Model | MGI Sequence Detail	8231	C57BL/6J
transcript	NM_008429	RefSeq | MGI Sequence Detail	3270	C57BL/6
polypeptide	P48543	UniProt | EBI | MGI Sequence Detail	393	Not Applicable

All sequences(28) RefSeq(2) UniProt(2)

Polymorphisms

SNPs(95 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR014756	Immunoglobulin E-set
InterPro	IPR016449	Potassium channel, inwardly rectifying, Kir
InterPro	IPR003276	Potassium channel, inwardly rectifying, Kir3.3
InterPro	IPR013518	Potassium channel, inwardly rectifying, Kir, cytoplasmic
Protein Ontology	PR:000002004	G protein-activated inward rectifier potassium channel 3

Graphical View of Protein Domain Structure

References

(Earliest) J:29320 Lesage F, et al., Cloning provides evidence for a family of inward rectifier and G-protein coupled K+ channels in the brain. FEBS Lett. 1994 Oct 10;353(1):37-42
(Latest) J:164262 Arora D, et al., Altered neurotransmission in the mesolimbic reward system of Girk mice. J Neurochem. 2010 Sep 1;114(5):1487-97
All references(59)

Other accession IDs

MGD-MRK-37041, MGI:1920728