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Kif3c Gene Detail
Summary
  • Symbol
    Kif3c
  • Name
    kinesin family member 3C
  • Synonyms
    N-4 kinesin
  • Feature Type
    protein coding gene
  • IDs
    MGI:107979
    NCBI Gene: 16570
  • Gene Overview
    MyGene.info: KIF3C
  • Alliance
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr12:3365132-3406494 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 12, 1.77 cM
  • Mapping Data
    5 experiments
Strain
Comparison
more
  • SNPs within 2kb
    111 from dbSNP Build 142
  • Strain Annotations
    18
  • PCR
  • RFLP
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_107979
protein coding gene Chr12:3365132-3406494 (.)
129S1/SvImJ MGP_129S1SvImJ_G0019556
protein coding gene Chr12:157056-200109 (+)
A/J MGP_AJ_G0019523
protein coding gene Chr12:227086-271895 (+)
AKR/J MGP_AKRJ_G0019493
protein coding gene Chr12:348493-392046 (+)
BALB/cJ MGP_BALBcJ_G0019498
protein coding gene Chr12:225107-270837 (+)
C3H/HeJ MGP_C3HHeJ_G0019304
protein coding gene Chr12:131049-175243 (+)
C57BL/6NJ MGP_C57BL6NJ_G0019948
protein coding gene Chr12:170255-211590 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0017572
protein coding gene Chr12:163259-203866 (+)
CAST/EiJ MGP_CASTEiJ_G0018859
protein coding gene Chr12:188624-228726 (+)
CBA/J MGP_CBAJ_G0019275
protein coding gene Chr12:375895-420990 (+)
DBA/2J MGP_DBA2J_G0019388
protein coding gene Chr12:181166-221668 (+)
FVB/NJ MGP_FVBNJ_G0019379
protein coding gene Chr12:198006-240636 (+)
LP/J MGP_LPJ_G0019459
protein coding gene Chr12:175847-222031 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0019412
protein coding gene Chr12:202090-243896 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0019986
protein coding gene Chr12:129890-169019 (+)
PWK/PhJ MGP_PWKPhJ_G0018625
protein coding gene Chr12:189190-231941 (+)
SPRET/EiJ MGP_SPRETEiJ_G0018416
protein coding gene Chr12:197281-239915 (+)
WSB/EiJ MGP_WSBEiJ_G0018911
protein coding gene Chr12:170057-212724 (+)



Homology
more
  • Human Ortholog
    KIF3C, kinesin family member 3C
  • Vertebrate Orthologs
    10
  • Human Ortholog
    KIF3C, kinesin family member 3C
    Orthology source: HomoloGene, HGNC
  • Links
    NCBI Gene ID: 3797
    neXtProt AC: NX_O14782
    UniProt: O14782

  • Chr Location
    2p23.3; chr2:25926586-25982574 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotypes from 4 alleles in 2 genetic backgrounds
    7 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Mice homozygous for disruptions in this gene display a normal phenotype.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 16570 NCBI Gene Model | MGI Sequence Detail 41363 C57BL/6J ±  kb
transcript NM_008445 RefSeq | MGI Sequence Detail 6849 C57BL/6  
polypeptide O35066 UniProt | EBI | MGI Sequence Detail 796 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 12
    cDNA 11
    Primer pair 1

    Microarray probesets 4
Other
Accession IDs
less
MGD-MRK-36559
References
more
  • Summaries
    All 41
    Developmental Gene Expression 3
    Gene Ontology 6
    Phenotypes 7
  • Earliest
    J:42822 Nakagawa T, et al., Identification and classification of 16 new kinesin superfamily (KIF) proteins in mouse genome. Proc Natl Acad Sci U S A. 1997 Sep 2;94(18):9654-9
  • Latest
    J:237348 Albracht CD, et al., Heterodimerization of Kinesin-2 KIF3AB Modulates Entry into the Processive Run. J Biol Chem. 2016 Oct 28;291(44):23248-23256

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory