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Cct6a Gene Detail
Summary
  • Symbol
    Cct6a
  • Name
    chaperonin containing Tcp1, subunit 6a (zeta)
  • Synonyms
    Cct6, Cctz-1, chaperonin containing TCP-1
Location & Maps
more
  • Sequence Map
    Chr5:129786998-129846371 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      59374 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 5, 68.26 cM
  • Mapping Data
    1 experiment
Homology
more
  • Human Ortholog
    CCT6A, chaperonin containing TCP1 subunit 6A
  • Vertebrate Orthologs
    10
  • Human Ortholog
    CCT6A, chaperonin containing TCP1 subunit 6A
    Orthology source: HomoloGene, HGNC
  • Synonyms
    CCT6, Cctz, CCT-zeta, CCT-zeta-1, HTR3, MoDP-2, TCP-1-zeta, TCP20, TCPZ, TTCP20
  • Links
    NCBI Gene ID: 908
    neXtProt AC: NX_P40227

  • Chr Location
    7p11.2; chr7:56051685-56063989 (+)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 1336
    1 human;1 mouse;1 rat;1 chimpanzee;1 rhesus macaque;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed
  • HCOP
    human homology predictions: CCT6A
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    11 phenotype references
  • All Mutations and Alleles
    29
  • Chemically induced (other)
    1
  • Gene trapped
    27
  • Radiation induced
    1
  • Genomic Mutations
    2 involving Cct6a
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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  • All Sequences
  • RefSeq
  • UniProt
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000055628 VEGA Gene Model | MGI Sequence Detail 59374 C57BL/6J ±  kb
transcript OTTMUST00000137670 VEGA | MGI Sequence Detail 2454 Not Applicable  
polypeptide P80317 UniProt | EBI | MGI Sequence Detail 531 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    181 from dbSNP Build 142
Protein
Information
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  • UniProt
    7 Sequences
  • Protein Ontology
    PR:000005154 T-complex protein 1 subunit zeta
  • InterPro Domains
    IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1)
    IPR002423 Chaperonin Cpn60/TCP-1 family
    IPR002194 Chaperonin TCP-1, conserved site
    IPR027409 GroEL-like apical domain
    IPR027413 GroEL-like equatorial domain
    IPR012722 T-complex protein 1, zeta subunit
    IPR027410 TCP-1-like chaperonin intermediate domain
Molecular
Reagents
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  • All nucleic 39
    cDNA 37
    Primer pair 2

    Microarray probesets 3
Other
Accession IDs
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MGD-MRK-36523
References
more
  • Summaries
    All 33
    Developmental Gene Expression 3
    Gene Ontology 9
    Phenotypes 11
  • Earliest
    J:25228 Kubota H, et al., Identification of six Tcp-1-related genes encoding divergent subunits of the TCP-1-containing chaperonin. Curr Biol. 1994 Feb 1;4(2):89-99
  • Latest
    J:197389 Slater LH, et al., CCT chaperonin complex is required for efficient delivery of anthrax toxin into the cytosol of host cells. Proc Natl Acad Sci U S A. 2013 Jun 11;110(24):9932-7

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/27/2016
MGI 6.05
The Jackson Laboratory