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Cct6a Gene Detail
Summary
  • Symbol
    Cct6a
  • Name
    chaperonin containing Tcp1, subunit 6a (zeta)
  • Synonyms
    Cct6, Cctz-1, chaperonin containing TCP-1
Location &
Maps
more
  • Sequence Map
    Chr5:129787356-129846443 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 5, 68.26 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    174 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_107943
protein coding gene Chr5:129786998-129846443 (.)
129S1/SvImJ MGP_129S1SvImJ_G0015615
unclassified non-coding RNA gene Chr5:133908537-133920986 (+)
A/J MGP_AJ_G0015591
unclassified non-coding RNA gene Chr5:128279507-128290482 (+)
AKR/J MGP_AKRJ_G0015555
unclassified non-coding RNA gene Chr5:132452015-132464235 (+)
BALB/cJ MGP_BALBcJ_G0015553
unclassified non-coding RNA gene Chr5:129628386-129638905 (+)
C3H/HeJ MGP_C3HHeJ_G0015375
unclassified non-coding RNA gene Chr5:133004661-133016372 (+)
C57BL/6NJ MGP_C57BL6NJ_G0016007
unclassified non-coding RNA gene Chr5:139041501-139052608 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0013741
unclassified non-coding RNA gene Chr5:122667187-122678429 (+)
CAST/EiJ MGP_CASTEiJ_G0014931
unclassified non-coding RNA gene Chr5:132302489-132318947 (+)
CBA/J MGP_CBAJ_G0015356
unclassified non-coding RNA gene Chr5:144451479-144463218 (+)
DBA/2J MGP_DBA2J_G0015450
unclassified non-coding RNA gene Chr5:128241933-128253728 (+)
FVB/NJ MGP_FVBNJ_G0015457
unclassified non-coding RNA gene Chr5:127335787-127346438 (+)
LP/J MGP_LPJ_G0015531
unclassified non-coding RNA gene Chr5:134418318-134429080 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0015480
unclassified non-coding RNA gene Chr5:147795350-147806115 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0016049
unclassified non-coding RNA gene Chr5:132137367-132148389 (+)
PWK/PhJ MGP_PWKPhJ_G0014716
unclassified non-coding RNA gene Chr5:127168784-127180467 (+)
SPRET/EiJ MGP_SPRETEiJ_G0014504
unclassified non-coding RNA gene Chr5:129697489-129708115 (+)
WSB/EiJ MGP_WSBEiJ_G0015035
unclassified non-coding RNA gene Chr5:132836393-132851502 (+)



Homology
more
  • Human Ortholog
    CCT6A, chaperonin containing TCP1 subunit 6A
  • Vertebrate Orthologs
    10
  • Human Ortholog
    CCT6A, chaperonin containing TCP1 subunit 6A
    Orthology source: HomoloGene, HGNC
  • Synonyms
    CCT6, Cctz, CCT-zeta, CCT-zeta-1, HTR3, MoDP-2, TCP-1-zeta, TCP20, TCPZ, TTCP20
  • Links
    NCBI Gene ID: 908
    neXtProt AC: NX_P40227
    UniProt: P40227

  • Chr Location
    7p11.2; chr7:56051685-56063989 (+)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 1336
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: CCT6A
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    11 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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  • All Sequences
  • RefSeq
  • UniProt
Representative SequencesLengthStrain/SpeciesFlank
genomic 12466 NCBI Gene Model | MGI Sequence Detail 59088 C57BL/6J ±  kb
transcript NM_009838 RefSeq | MGI Sequence Detail 2303 C57BL/6  
polypeptide P80317 UniProt | EBI | MGI Sequence Detail 531 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    7 Sequences
  • InterPro Domains
    IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1)
    IPR002423 Chaperonin Cpn60/TCP-1 family
    IPR002194 Chaperonin TCP-1, conserved site
    IPR027409 GroEL-like apical domain superfamily
    IPR027413 GroEL-like equatorial domain superfamily
    IPR012722 T-complex protein 1, zeta subunit
    IPR027410 TCP-1-like chaperonin intermediate domain superfamily
Molecular
Reagents
less
  • All nucleic 40
    cDNA 38
    Primer pair 2

    Microarray probesets 3
Other
Accession IDs
less
MGD-MRK-36523
References
more
  • Summaries
    All 40
    Developmental Gene Expression 3
    Gene Ontology 11
    Phenotypes 11
  • Earliest
    J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
  • Latest
    J:197389 Slater LH, et al., CCT chaperonin complex is required for efficient delivery of anthrax toxin into the cytosol of host cells. Proc Natl Acad Sci U S A. 2013 Jun 11;110(24):9932-7

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory