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Tfb2m
Gene Detail
Symbol

Name
ID
Tfb2m
transcription factor B2, mitochondrial
MGI:107937
Synonyms
Hkp1
Feature Type
protein coding gene
Genetic Map
Chromosome 1
83.56 cM, cytoband H3
Detailed Genetic Map ± 1 cM


Mapping data(4)
Sequence Map
Chr1:179528055-179546267 bp, - strand
From VEGA annotation of GRCm38

  18213 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:7362  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: TFB2M
Protein SuperFamily: mitochondrial dimethyladenosine transferase 2, mitochondrial precursor
Gene Tree: Tfb2m

Human
homologs
TFB2M, transcription factor B2, mitochondrial
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 64216
neXtProt AC: NX_Q9H5Q4

Human Synonyms: Hkp1, mtTFB2

Human Chr (Location): 1q44; chr1:246540561-246566319 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(2) : Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Tfb2m interacts with 197 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (5 records)
Data Summary: Results (307)    Tissues (80)    Images (24)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 210
RT-PCR 97
cDNA source data(71)
Other mouse links: GEO   Expression Atlas
Other vertebrate links: Xenbase tfb2m ; ZFIN tfb2m    NEW 
Molecular
reagents
All nucleic(75) cDNA(71) Primer pair(4)
Microarray probesets(5)
Other database
links
VEGA Gene Model OTTMUSG00000022545 (Evidence)
Ensembl Gene Model ENSMUSG00000026492 (Evidence)
Entrez Gene 15278 (Evidence)
UniGene 293529
DFCI TC1574858
NIA Mouse Gene Index U022134, U033926
EC 2.1.1.-
Consensus CDS Project CCDS15561.1
International Mouse Phenotyping Consortium Status Tfb2m
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000022545 VEGA Gene Model | MGI Sequence Detail 18213 C57BL/6J ±  kb
transcript OTTMUST00000054001 VEGA | MGI Sequence Detail 2449 Not Applicable 
polypeptide OTTMUSP00000025719 VEGA | MGI Sequence Detail 396 Not Applicable 

For the selected sequences
All sequences(47) RefSeq(8) UniProt(2)
Polymorphisms
PCR(1) : SNPs within 2kb(124 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR016861 Mitochondrial dimethyladenosine transferase 2, mitochondrial precursor
InterPro IPR001737 Ribosomal RNA adenine methylase transferase
Protein Ontology PR:000016268 dimethyladenosine transferase 2, mitochondrial
References
(Earliest) J:44483 Brady KP, et al., Genetic mapping of 262 loci derived from expressed sequences in a murine interspecific cross using single-strand conformational polymorphism analysis. Genome Res. 1997 Nov;7(11):1085-93
(Latest) J:185743 Cotney J, et al., Chromatin state signatures associated with tissue-specific gene expression and enhancer activity in the embryonic limb. Genome Res. 2012 Jun;22(6):1069-80
All references(37)
Other
accession IDs
MGD-MRK-36517

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
08/18/2015
MGI 6.0
The Jackson Laboratory