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Wnt8a Gene Detail
Summary
  • Symbol
    Wnt8a
  • Name
    wingless-type MMTV integration site family, member 8A
  • Synonyms
    Stra11
  • Feature Type
    protein coding gene
  • IDs
    MGI:107924
    NCBI Gene: 20890
Location & Maps
more
  • Sequence Map
    Chr18:34542328-34548061 bp, + strand
  • From NCBI annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      5734 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 18, 18.69 cM, cytoband B3
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    WNT8A, Wnt family member 8A
  • Vertebrate Orthologs
    10
  • Human Ortholog
    WNT8A, Wnt family member 8A
    Orthology source: HomoloGene, HGNC
  • Synonyms
    WNT8D
  • Links
    NCBI Gene ID: 7478
    neXtProt AC: NX_Q9H1J5
    UniProt: Q9H1J5

  • Chr Location
    5q31.2; chr5:138077367-138092900 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    1 phenotype from multigenic genotypes
    5 phenotype references
Mice homozygous for a knock-out allele are viable and fertile.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 20890 NCBI Gene Model | MGI Sequence Detail 5734 C57BL/6J ±  kb
transcript NM_009290 RefSeq | MGI Sequence Detail 1519 C57BL/6  
polypeptide Q64527 UniProt | EBI | MGI Sequence Detail 354 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    38 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 28
    cDNA 15
    Primer pair 10
    Other 3

    Microarray probesets 3
Other
Accession IDs
less
MGD-MRK-36504
References
more
  • Summaries
    All 84
    Developmental Gene Expression 60
    Gene Ontology 6
    Phenotypes 5
  • Earliest
    J:28316 Bouillet P, et al., Efficient cloning of cDNAs of retinoic acid-responsive genes in P19 embryonal carcinoma cells and characterization of a novel mouse gene, Stra1 (mouse LERK-2/Eplg2). Dev Biol. 1995 Aug;170(2):420-33
  • Latest
    J:239523 Chen CM, et al., Wnt5a is essential for hippocampal dendritic maintenance and spatial learning and memory in adult mice. Proc Natl Acad Sci U S A. 2017 Jan 24;114(4):E619-E628

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/08/2017
MGI 6.10
The Jackson Laboratory