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Wnt8a Gene Detail
Summary
  • Symbol
    Wnt8a
  • Name
    wingless-type MMTV integration site family, member 8A
  • Synonyms
    Stra11
  • Feature Type
    protein coding gene
  • IDs
    MGI:107924
    NCBI Gene: 20890
Location & Maps
more
  • Sequence Map
    Chr18:34542313-34548273 bp, + strand
  • From Ensembl annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      5961 bp   ±  kb flank

  • Genome Browsers
Homology
more
  • Human Ortholog
    WNT8A, Wnt family member 8A
  • Vertebrate Orthologs
    10
  • Human Ortholog
    WNT8A, Wnt family member 8A
    Orthology source: HGNC, HomoloGene
  • Synonyms
    WNT8D
  • Links
    NCBI Gene ID: 7478
    neXtProt AC: NX_Q9H1J5

  • Chr Location
    5q31; chr5:138083892-138096730 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    1 phenotype from multigenic genotypes
    5 phenotype references
  • All Mutations and Alleles
    2
  • Gene trapped
    1
  • Targeted
    1
  • Incidental Mutations
Mice homozygous for a knock-out allele are viable and fertile.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000012282 Ensembl Gene Model | MGI Sequence Detail 5961 C57BL/6J ±  kb
transcript ENSMUST00000012426 Ensembl | MGI Sequence Detail 1746 Not Applicable  
polypeptide ENSMUSP00000012426 Ensembl | MGI Sequence Detail 354 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    39 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 27
    cDNA 15
    Primer pair 9
    Other 3

    Microarray probesets 3
Other
Accession IDs
less
MGD-MRK-36504
References
more
  • Summaries
    All 83
    Developmental Gene Expression 59
    Gene Ontology 6
    Phenotypes 5
  • Earliest
    J:28316 Bouillet P, et al., Efficient cloning of cDNAs of retinoic acid-responsive genes in P19 embryonal carcinoma cells and characterization of a novel mouse gene, Stra1 (mouse LERK-2/Eplg2). Dev Biol. 1995 Aug;170(2):420-33
  • Latest
    J:226692 Wright KD, et al., Cooperative and independent functions of FGF and Wnt signaling during early inner ear development. BMC Dev Biol. 2015;15:33

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
04/26/2016
MGI 6.03
The Jackson Laboratory