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Wnt8a
Gene Detail
 Symbol
Name
ID
Wnt8a
wingless-type MMTV integration site family, member 8A
MGI:107924
Synonyms Stra11
Feature Type protein coding gene
Genetic Map
Chromosome 18
18.69 cM, cytoband B3
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr18:34542328-34548061 bp, + strand
From NCBI annotation of GRCm38

  5734 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:7553  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: int-1 transforming protein
Gene Tree: Wnt8a

Human
homologs
Human Homolog WNT8A, wingless-type MMTV integration site family, member 8A
NCBI Gene ID 7478
neXtProt AC  NX_Q9H1J5
Human Synonyms  WNT8D
Human Chr (Location)  5q31; chr5:138083892-138092648 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(2) : Gene trapped(1) Targeted(1)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a knock-out allele are viable and fertile.
 
Interactions
Wnt8a interacts with 58 markers (Mir15a, Mir22, Mir24-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (20 annotations)
Process cell fate commitment, cell morphogenesis, ...
Component extracellular region, extracellular space, ...
Function frizzled binding, protein binding, ...
This is a GO Consortium Reference Genome Project gene.
External Resources: FuncBase
Expression
Literature Summary: (54 records)
Data Summary: Results (491)    Tissues (434)    Images (55)
Theiler Stages: 5, 8, 9, 11, 12, 13, 15, 17, 19, 20, 21, 22, 23, 24, 25, 26, 28
Assay TypeResults
RNA in situ 466
RT-PCR 23
RNase protection 2
cDNA source data(13)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(26) cDNA(15) Primer pair(8) Other(3)
Microarray probesets(3)
Other database
links
Ensembl Gene ModelENSMUSG00000012282 (Evidence)
Entrez Gene20890 (Evidence)
UniGene558
DFCITC1595915
DoTSDT.40157754, DT.94226319
NIA Mouse Gene IndexU018541
Consensus CDS ProjectCCDS29129.1
International Mouse Knockout Project StatusWnt8a
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 20890 NCBI Gene Model | MGI Sequence Detail 5734 C57BL/6J ±  kb
transcript NM_009290 RefSeq | MGI Sequence Detail 1519 C57BL/6 
polypeptide Q64527 UniProt | EBI | MGI Sequence Detail 354 Not Applicable 

For the selected sequences
All sequences(18) RefSeq(4) UniProt(2)
Polymorphisms SNPs within 2kb(37 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR005817 Wnt
InterPro IPR013301 Wnt-8 protein
InterPro IPR018161 Wnt protein, conserved site
Protein Ontology PR:000017450 protein Wnt-8a
Graphical View of Protein Domain Structure
References (Earliest) J:28316 Bouillet P, et al., Efficient cloning of cDNAs of retinoic acid-responsive genes in P19 embryonal carcinoma cells and characterization of a novel mouse gene, Stra1 (mouse LERK-2/Eplg2). Dev Biol. 1995 Aug;170(2):420-33
(Latest) J:207612 Zhang L, et al., Ectodermal Wnt signaling regulates abdominal myogenesis during ventral body wall development. Dev Biol. 2014 Mar 1;387(1):64-72
All references(83)
Other
accession IDs
MGD-MRK-36504

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/12/2014
MGI 5.19
The Jackson Laboratory