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Stra8
Gene Detail
 Symbol
Name
ID
Stra8
stimulated by retinoic acid gene 8
MGI:107917
Feature Type protein coding gene
Genetic Map
Chromosome 6
15.20 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr6:34920163-34939344 bp, + strand
From VEGA annotation of GRCm38

  19182 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:49197  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog

Gene Tree: Stra8

Human
homologs
Human Homolog STRA8, stimulated by retinoic acid 8
NCBI Gene ID 346673
neXtProt AC  NX_Q7Z7C7
Human Chr (Location)  7q33; chr7:135231979-135258492 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(16) : Gene trapped(10) Targeted(6)
Incidental mutations (data from APF )
 
Homozygous null mice display impaired meiosis.
 
Interactions
Stra8 interacts with 27 markers (Mir34b, Mir34c, Mir122a, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (17 annotations)
Process cellular response to retinoic acid, DNA replication, ...
Component cytoplasm, nucleus
Function protein binding
External Resources: FuncBase
Expression
Literature Summary: (46 records)
Data Summary: Results (145)    Tissues (40)    Images (48)
Theiler Stages: 2, 3, 11, 17, 20, 21, 22, 23, 24, 25, 27, 28
Assay TypeResults
RNA in situ 97
RT-PCR 48
cDNA source data(10)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(17) cDNA(10) Primer pair(5) Other(2)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000022789 (Evidence)
Ensembl Gene ModelENSMUSG00000029848 (Evidence)
Entrez Gene20899 (Evidence)
UniGene5171
DFCITC1589404
DoTSDT.110498857, DT.87065622
NIA Mouse Gene IndexU006667
Consensus CDS ProjectCCDS39458.1
International Mouse Knockout Project StatusStra8
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000022789 VEGA Gene Model | MGI Sequence Detail 19182 C57BL/6J ±  kb
transcript OTTMUST00000054740 VEGA | MGI Sequence Detail 1803 Not Applicable 
polypeptide OTTMUSP00000026155 VEGA | MGI Sequence Detail 393 Not Applicable 

For the selected sequences
All sequences(37) RefSeq(6) UniProt(3)
Polymorphisms SNPs within 2kb(100 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
Protein Ontology PR:000015773 stimulated by retinoic acid gene 8 protein
References (Earliest) J:28316 Bouillet P, et al., Efficient cloning of cDNAs of retinoic acid-responsive genes in P19 embryonal carcinoma cells and characterization of a novel mouse gene, Stra1 (mouse LERK-2/Eplg2). Dev Biol. 1995 Aug;170(2):420-33
(Latest) J:209944 Busada JT, et al., Retinoic acid induces multiple hallmarks of the prospermatogonia-to-spermatogonia transition in the neonatal mouse. Biol Reprod. 2014 Mar;90(3):64
All references(89)
Other
accession IDs
MGD-MRK-36497

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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Funding Information
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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory