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Ssrp1
Gene Detail
Symbol

Name
ID
Ssrp1
structure specific recognition protein 1
MGI:107912
Synonyms
Hmg1-rs1, Hmgi-rs3, Hmgox, T160
Feature Type
protein coding gene
Genetic Map
Chromosome 2
49.45 cM
Detailed Genetic Map ± 1 cM


Mapping data(7)
Sequence Map
Chr2:85037234-85047109 bp, + strand
From VEGA annotation of GRCm38

  9876 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:110735  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: Ssrp1

Human
homologs
Human Homolog SSRP1, structure specific recognition protein 1
NCBI Gene ID 6749
neXtProt AC  NX_Q08945
Human Synonyms  FACT, FACT80, T160
Human Chr (Location)  11q12; chr11:57325985-57335877 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(48) : Gene trapped(42) Targeted(6)
Genomic Mutations involving Ssrp1 (2)
Incidental mutations (data from Mutagenetix , APF )
 
Disruption of this gene is lethal resulting in death at some point between implantation and E5.5.
 
Interactions
Ssrp1 interacts with 107 markers (Mir15a, Mir15b, Mir16-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (14 annotations)
Process cellular response to DNA damage stimulus, chromatin remodeling, ...
Component chromosome, cytoplasm, ...
Function chromatin binding, DNA binding, ...
External Resources: FuncBase
Expression
Literature Summary: (5 records)
Data Summary: Results (60)    Tissues (60)    Images (5)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 52
RT-PCR 8
cDNA source data(24)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(29) Genomic(4) cDNA(24) Primer pair(1)
Microarray probesets(5)
Other database
links
VEGA Gene ModelOTTMUSG00000013453 (Evidence)
Ensembl Gene ModelENSMUSG00000027067 (Evidence)
Entrez Gene20833 (Evidence)
DFCITC1605177, TC1573421, TC1682288
DoTSDT.101281203, DT.101212875, DT.103572352, DT.99865406, DT.97396683
NIA Mouse Gene IndexU002003
Consensus CDS ProjectCCDS38165.1
International Mouse Knockout Project StatusSsrp1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000013453 VEGA Gene Model | MGI Sequence Detail 9876 C57BL/6J ±  kb
transcript OTTMUST00000032520 VEGA | MGI Sequence Detail 2739 Not Applicable 
polypeptide OTTMUSP00000014446 VEGA | MGI Sequence Detail 708 Not Applicable 

For the selected sequences
All sequences(71) RefSeq(6) UniProt(5)
Polymorphisms
RFLP(2) : SNPs within 2kb(59 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR013719 Domain of unknown function DUF1747
InterPro IPR009071 High mobility group (HMG) box domain
InterPro IPR011993 Pleckstrin homology-like domain
InterPro IPR024954 SSRP1 domain
InterPro IPR000969 Structure-specific recognition protein
Protein Ontology PR:000015663 FACT complex subunit SSRP1
References
(Earliest) J:11384 Shirakata M, et al., HMG1-related DNA-binding protein isolated with V-(D)-J recombination signal probes. Mol Cell Biol. 1991 Sep;11(9):4528-36
(Latest) J:183708 Vethantham V, et al., Dynamic loss of H2B ubiquitylation without corresponding changes in H3K4 trimethylation during myogenic differentiation. Mol Cell Biol. 2012 Mar;32(6):1044-55
All references(49)
Other
accession IDs
MGD-MRK-10749, MGD-MRK-10799, MGD-MRK-28178, MGD-MRK-36492, MGI:2139516

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/16/2014
MGI 5.20
The Jackson Laboratory