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Fam3c Gene Detail
Summary
  • Symbol
    Fam3c
  • Name
    family with sequence similarity 3, member C
  • Synonyms
    D6Wsu176e, Fam3c
  • Feature Type
    protein coding gene
  • IDs
    MGI:107892
    NCBI Gene: 27999
  • Gene Overview
    MyGene.info: FAM3C
Location & Maps
more
  • Sequence Map
    Chr6:22306520-22356243 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      49724 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 6, 9.24 cM
  • Mapping Data
    4 experiments
Homology
more
  • Human Ortholog
    FAM3C, family with sequence similarity 3 member C
  • Vertebrate Orthologs
    10
  • Human Ortholog
    FAM3C, family with sequence similarity 3 member C
    Orthology source: HGNC, HomoloGene
  • Synonyms
    GS3786, ILEI
  • Links
    NCBI Gene ID: 10447
    neXtProt AC: NX_Q92520

  • Chr Location
    7q31; chr7:121348245-121396369 (-)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 8926
    1 human;1 mouse;1 rat;1 chimpanzee;1 rhesus macaque;1 cattle;1 dog;1 chicken;1 western clawed frog;1 zebrafish
  • HCOP
    human homology predictions: FAM3C
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 3 alleles in 1 genetic background
    9 phenotype references
  • All Mutations and Alleles
    114
  • Gene trapped
    110
  • Targeted
    4
  • Incidental Mutations
    APF
Mice homozygous for a knock-out or gene trap allele exhibit normal skeletal phenotype.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000035360 VEGA Gene Model | MGI Sequence Detail 49724 C57BL/6J ±  kb
transcript OTTMUST00000090297 VEGA | MGI Sequence Detail 1617 Not Applicable  
polypeptide OTTMUSP00000049502 VEGA | MGI Sequence Detail 247 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    405 from dbSNP Build 142
Protein
Information
less
  • UniProt
    6 Sequences
  • Protein Ontology
    PR:000029492 protein FAM3C
Molecular
Reagents
less
  • All nucleic 12
    cDNA 11
    Primer pair 1

    Microarray probesets 6
Other
Accession IDs
less
MGD-MRK-36470
References
more
  • Summaries
    All 36
    Developmental Gene Expression 4
    Gene Ontology 2
    Phenotypes 9
  • Earliest
    J:50869 Ko MSH, et al., Genome-wide mapping of unselected transcripts from extraembryonic tissue of 7.5-day mouse embryos reveals enrichment in the t-complex and under-representation on the X chromosome. Hum Mol Genet. 1998 Nov;7(12):1967-78
  • Latest
    J:188156 Zheng HF, et al., WNT16 influences bone mineral density, cortical bone thickness, bone strength, and osteoporotic fracture risk. PLoS Genet. 2012 Jul;8(7):e1002745

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/19/2016
MGI 6.04
The Jackson Laboratory