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Fam3c
Gene Detail
Symbol

Name
ID
Fam3c
family with sequence similarity 3, member C
MGI:107892
Synonyms
D6Wsu176e, Fam3c
Feature Type
protein coding gene
Genetic Map
Chromosome 6
9.24 cM
Detailed Genetic Map ± 1 cM


Mapping data(4)
Sequence Map
Chr6:22306520-22356243 bp, - strand
From VEGA annotation of GRCm38

  49724 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:8926  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: FAM3C
Gene Tree: Fam3c

Human
homologs
FAM3C, family with sequence similarity 3, member C
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 10447
neXtProt AC: NX_Q92520

Human Synonyms: GS3786, ILEI

Human Chr (Location): 7q31; chr7:121348245-121396369 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(114) : Gene trapped(110) Targeted(4)
Incidental mutations (data from APF )
 
Mice homozygous for a knock-out or gene trap allele exhibit normal skeletal phenotype.
 
Interactions
Fam3c interacts with 261 markers (Mir7-1, Mir9-1, Mir9-2, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (6 annotations)
Process multicellular organismal development
Component cytoplasmic vesicle, extracellular exosome, ...
Function molecular_function
External Resources: FuncBase
Expression
Literature Summary: (3 records)
Data Summary: Results (17)    Tissues (8)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 11
RT-PCR 6
cDNA source data(10)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase fam3c ; ZFIN fam3c    NEW 
Molecular
reagents
All nucleic(12) cDNA(11) Primer pair(1)
Microarray probesets(6)
Other database
links
VEGA Gene Model OTTMUSG00000035360 (Evidence)
Ensembl Gene Model ENSMUSG00000029672 (Evidence)
Entrez Gene 27999 (Evidence)
DFCI TC1576079, TC1654950, TC1606749
DoTS DT.101703861, DT.102543498, DT.91319320, DT.531930
NIA Mouse Gene Index U027075
Consensus CDS Project CCDS39436.1
International Mouse Phenotyping Consortium Status Fam3c
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000035360 VEGA Gene Model | MGI Sequence Detail 49724 C57BL/6J ±  kb
transcript OTTMUST00000090297 VEGA | MGI Sequence Detail 1617 Not Applicable 
polypeptide OTTMUSP00000049502 VEGA | MGI Sequence Detail 247 Not Applicable 

For the selected sequences
All sequences(66) RefSeq(8) UniProt(7)
Polymorphisms
SNPs within 2kb(406 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR026101 FAM3
Protein Ontology PR:000029492 protein FAM3C
References
(Earliest) J:50869 Ko MSH, et al., Genome-wide mapping of unselected transcripts from extraembryonic tissue of 7.5-day mouse embryos reveals enrichment in the t-complex and under-representation on the X chromosome. Hum Mol Genet. 1998 Nov;7(12):1967-78
(Latest) J:188156 Zheng HF, et al., WNT16 influences bone mineral density, cortical bone thickness, bone strength, and osteoporotic fracture risk. PLoS Genet. 2012 Jul;8(7):e1002745
All references(38)
Other
accession IDs
MGD-MRK-36470

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/21/2015
MGI 5.22
The Jackson Laboratory