About   Help   FAQ
Uqcrc1 Gene Detail
Summary
  • Symbol
    Uqcrc1
  • Name
    ubiquinol-cytochrome c reductase core protein 1
  • Synonyms
    1110032G10Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:107876
    NCBI Gene: 22273
  • Gene Overview
    MyGene.info: UQCRC1
Location & Maps
more
  • Sequence Map
    Chr9:108936633-108949623 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      12991 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 9, 59.63 cM
  • Mapping Data
    3 experiments
Homology
more
  • Human Ortholog
    UQCRC1, ubiquinol-cytochrome c reductase core protein I
  • Vertebrate Orthologs
    10
  • Human Ortholog
    UQCRC1, ubiquinol-cytochrome c reductase core protein I
    Orthology source: HomoloGene, HGNC
  • Synonyms
    D3S3191, QCR1, UQCR1
  • Links
    NCBI Gene ID: 7384
    neXtProt AC: NX_P31930

  • Chr Location
    3p21.3; chr3:48598999-48609665 (-)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 2525
    1 human;1 mouse;1 rat;1 chimpanzee;1 rhesus macaque;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed
  • HCOP
    human homology predictions: UQCRC1
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
  • All Mutations and Alleles
    7
  • Gene trapped
    7
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000051043 VEGA Gene Model | MGI Sequence Detail 12991 C57BL/6J ±  kb
transcript OTTMUST00000129398 VEGA | MGI Sequence Detail 1653 Not Applicable  
polypeptide OTTMUSP00000069507 VEGA | MGI Sequence Detail 480 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    42 from dbSNP Build 142
Protein
Information
less
  • UniProt
    9 Sequences
  • Protein Ontology
    PR:000017124 cytochrome b-c1 complex subunit 1, mitochondrial
  • InterPro Domains
    IPR011249 Metalloenzyme, LuxS/M16 peptidase-like
    IPR007863 Peptidase M16, C-terminal
    IPR011237 Peptidase M16 domain
    IPR011765 Peptidase M16, N-terminal
Molecular
Reagents
less
  • All nucleic 396
    cDNA 394
    Primer pair 2

    Microarray probesets 3
Other
Accession IDs
less
MGD-MRK-36453, MGI:1913436
References
more
  • Summaries
    All 46
    Developmental Gene Expression 6
    Gene Ontology 13
    Phenotypes 5
  • Earliest
    J:44483 Brady KP, et al., Genetic mapping of 262 loci derived from expressed sequences in a murine interspecific cross using single-strand conformational polymorphism analysis. Genome Res. 1997 Nov;7(11):1085-93
  • Latest
    J:173130 Ghezzi D, et al., Mutations in TTC19 cause mitochondrial complex III deficiency and neurological impairment in humans and flies. Nat Genet. 2011 Mar;43(3):259-63

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
09/20/2016
MGI 6.05
The Jackson Laboratory