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Tubb2a Gene Detail
Summary
  • Symbol
    Tubb2a
  • Name
    tubulin, beta 2A class IIA
  • Feature Type
    protein coding gene
  • IDs
    MGI:107861
    NCBI Gene: 22151
  • Gene Overview
    MyGene.info: TUBB2A
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr13:34074278-34078008 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 13, 14.03 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    48 from dbSNP Build 142
  • Strain Annotations
    15
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_107861
protein coding gene Chr13:34074274-34078008 (-)
129S1/SvImJ MGP_129S1SvImJ_G0020447
protein coding gene Chr13:32181851-32185991 (-)
A/J no annotation
AKR/J MGP_AKRJ_G0020379
protein coding gene Chr13:31974556-31980012 (-)
BALB/cJ MGP_BALBcJ_G0019544
protein coding gene Chr12:8980875-8983266 (-)
C3H/HeJ MGP_C3HHeJ_G0020197
protein coding gene Chr13:31972672-31979758 (-)
C57BL/6NJ MGP_C57BL6NJ_G0021055
protein coding gene Chr13:64963864-64965088 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0018418
protein coding gene Chr13:29551290-29555102 (-)
CAST/EiJ MGP_CASTEiJ_G0019712
protein coding gene Chr13:31561645-31566343 (-)
CBA/J MGP_CBAJ_G0020156
protein coding gene Chr13:34691672-34705916 (-)
DBA/2J MGP_DBA2J_G0020278
protein coding gene Chr13:30766733-30772856 (-)
FVB/NJ MGP_FVBNJ_G0020258
protein coding gene Chr13:30343546-30347338 (-)
LP/J MGP_LPJ_G0020354
protein coding gene Chr13:32406827-32422640 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0020289
protein coding gene Chr13:34972634-34977320 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0020874
protein coding gene Chr13:31634505-31639789 (-)
PWK/PhJ no annotation
SPRET/EiJ MGP_SPRETEiJ_G0019292
protein coding gene Chr13:30287415-30290261 (-)
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    TUBB2A, tubulin beta 2A class IIa
  • Vertebrate Orthologs
    7
  • Human Ortholog
    TUBB2A, tubulin beta 2A class IIa
    Orthology source: HGNC, HomoloGene
  • Synonyms
    CDCBM5, TUBB, TUBB2
  • Links
    NCBI Gene ID: 7280
    neXtProt AC: NX_Q13885
    UniProt: Q13885

  • Chr Location
    6p25.2; chr6:3153666-3157549 (-)  GRCh38.p7

Human Diseases
more
  • Diseases
    1 with human TUBB2A associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    12 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 22151 NCBI Gene Model | MGI Sequence Detail 3731 C57BL/6J ±  kb
transcript NM_009450 RefSeq | MGI Sequence Detail 1638 C57BL/6  
polypeptide Q7TMM9 UniProt | EBI | MGI Sequence Detail 445 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 186
    cDNA 183
    Primer pair 3

    Microarray probesets 5
Other
Accession IDs
less
MGD-MRK-36438
References
more
  • Summaries
    All 52
    Developmental Gene Expression 14
    Gene Ontology 5
    Phenotypes 12
  • Earliest
    J:182573 Roderick TH, Producing and detecting paracentric chromosomal inversions in mice. Mutat Res. 1971 Jan;11(1):59-69
  • Latest
    J:259186 Heng X, et al., Analogous mechanism regulating formation of neocortical basal radial glia and cerebellar Bergmann glia. Elife. 2017 May 10;6

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/04/2018
MGI 6.13
The Jackson Laboratory