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Dgcr14 Gene Detail
Summary
  • Symbol
    Dgcr14
  • Name
    DiGeorge syndrome critical region gene 14
  • Synonyms
    D16H22S1269E, Dgsi, ES2, Es2el
  • Feature Type
    protein coding gene
  • IDs
    MGI:107854
    NCBI Gene: 27886
  • Gene Overview
    MyGene.info: DGCR14
Location & Maps
more
  • Sequence Map
    Chr16:17900711-17911348 bp, - strand
  • From Ensembl annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      10638 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 16, 11.09 cM, cytoband B1-B3
  • Mapping Data
    15 experiments
Homology
more
  • Human Ortholog
    DGCR14, DiGeorge syndrome critical region gene 14
  • Vertebrate Orthologs
    10
  • Human Ortholog
    DGCR14, DiGeorge syndrome critical region gene 14
    Orthology source: HomoloGene, HGNC
  • Synonyms
    DGCR13, DGSH, DGS-H, DGSI, DGS-I, ES2, Es2el
  • Links
    NCBI Gene ID: 8220
    neXtProt AC: NX_Q96DF8
    UniProt: Q96DF8

  • Chr Location
    22q11.21; chr22:19130279-19144726 (-)  GRCh38.p7

Human Diseases
more
  • Diseases
    1 with human DGCR14 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

  • References
    13 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    51 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000003527 Ensembl Gene Model | MGI Sequence Detail 10638 C57BL/6J ±  kb
transcript ENSMUST00000003621 Ensembl | MGI Sequence Detail 2819 Not Applicable  
polypeptide ENSMUSP00000003621 Ensembl | MGI Sequence Detail 480 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    43 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 109
    Genomic 27
    cDNA 78
    Primer pair 4

    Microarray probesets 6
Other
Accession IDs
less
MGD-MRK-36431, MGI:2146439, MGI:892008
References
more
  • Summaries
    All 88
    Developmental Gene Expression 9
    Diseases 13
    Gene Ontology 3
    Phenotypes 51
  • Earliest
    J:15242 Halford S, et al., Isolation of a gene expressed during early embryogenesis from the region of 22q11 commonly deleted in DiGeorge syndrome. Hum Mol Genet. 1993 Oct;2(10):1577-82
  • Latest
    J:235604 Nilsson SR, et al., Assessing the Cognitive Translational Potential of a Mouse Model of the 22q11.2 Microdeletion Syndrome. Cereb Cortex. 2016 Oct;26(10):3991-4003

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
03/14/2017
MGI 6.08
The Jackson Laboratory