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Ndufv1 Gene Detail
Summary
  • Symbol
    Ndufv1
  • Name
    NADH dehydrogenase (ubiquinone) flavoprotein 1
  • Synonyms
    24 kDa (FP)
  • Feature Type
    protein coding gene
  • IDs
    MGI:107851
    NCBI Gene: 17995
  • Gene Overview
    MyGene.info: NDUFV1
Location & Maps
more
Homology
more
  • Human Ortholog
    NDUFV1, NADH:ubiquinone oxidoreductase core subunit V1
  • Vertebrate Orthologs
    9
  • Human Ortholog
    NDUFV1, NADH:ubiquinone oxidoreductase core subunit V1
    Orthology source: HGNC, HomoloGene
  • Synonyms
    CI-51K, CI51KD, UQOR1
  • Links
    NCBI Gene ID: 4723
    neXtProt AC: NX_P49821

  • Chr Location
    11q13; chr11:67606852-67612541 (+)  GRCh38.p2

Human Diseases
more
  • Diseases
    1 with human NDUFV1 associations

Human Disease Mouse Models
       Mitochondrial Complex I Deficiency   OMIM: 252010
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000034058 VEGA Gene Model | MGI Sequence Detail 5310 C57BL/6J ±  kb
transcript OTTMUST00000086022 VEGA | MGI Sequence Detail 1661 Not Applicable  
polypeptide OTTMUSP00000046526 VEGA | MGI Sequence Detail 464 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    32 from dbSNP Build 142
Protein
Information
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  • UniProt
    6 Sequences
  • Protein Ontology
    PR:000011104 NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial
  • EC
  • InterPro Domains
    IPR001949 NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site
    IPR011538 NADH-ubiquinone oxidoreductase 51 kDa subunit, FMN-binding domain
    IPR019575 NADH-ubiquinone oxidoreductase 51 kDa subunit, iron-sulphur binding domain
    IPR011537 NADH ubiquinone oxidoreductase, F subunit
    IPR019554 Soluble ligand binding domain
Molecular
Reagents
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  • All nucleic 270
    cDNA 266
    Primer pair 3
    Other 1

    Microarray probesets 4
Other
Accession IDs
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MGD-MRK-36428
References
more
  • Summaries
    All 42
    Developmental Gene Expression 5
    Gene Ontology 9
    Phenotypes 6
  • Earliest
    J:44483 Brady KP, et al., Genetic mapping of 262 loci derived from expressed sequences in a murine interspecific cross using single-strand conformational polymorphism analysis. Genome Res. 1997 Nov;7(11):1085-93
  • Latest
    J:204025 Hatle KM, et al., MCJ/DnaJC15, an endogenous mitochondrial repressor of the respiratory chain that controls metabolic alterations. Mol Cell Biol. 2013 Jun;33(11):2302-14

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
04/19/2016
MGI 6.03
The Jackson Laboratory