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Ndufv1
Gene Detail
Symbol

Name
ID
Ndufv1
NADH dehydrogenase (ubiquinone) flavoprotein 1
MGI:107851
Synonyms
24 kDa (FP)
Feature Type
protein coding gene
Genetic Map
Chromosome 19
3.72 cM
Detailed Genetic Map ± 1 cM


Mapping data(4)
Sequence Map
Chr19:4007497-4012806 bp, - strand
From VEGA annotation of GRCm38

  5310 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:5151  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: NDUFV1
Protein SuperFamily: NADH-ubiquinone oxidoreductase, 51 kDa subunit
Gene Tree: Ndufv1

Human
homologs
NDUFV1, NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa
Orthology source: HomoloGene, HGNC

IDs:
NCBI Gene ID: 4723
neXtProt AC: NX_P49821

Human Synonyms: CI-51K, CI51KD, UQOR1

Human Chr (Location): 11q13; chr11:67606852-67612541 (+)  GRCh38.p2

Disease Associations: (1) Diseases Associated with Human NDUFV1

Mutations,
alleles, and
phenotypes
All mutations/alleles(9) : Gene trapped(8) Targeted(1)
Incidental mutations (data from Mutagenetix , APF , CvDC )
Interactions
Ndufv1 interacts with 57 markers (Mir34c, Mir96, Mir127, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (20 annotations)
Process oxidation-reduction process, transport
Component membrane, mitochondrial inner membrane, ...
Function 4 iron, 4 sulfur cluster binding, FMN binding, ...
This is a GO Consortium Reference Genome Project gene.
External Resources: FuncBase
Expression
Literature Summary: (5 records)
Data Summary: Results (165)    Tissues (105)    Images (24)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 163
RT-PCR 2
cDNA source data(266)
Other mouse links: Allen Institute   GENSAT   GEO   Expression Atlas
Other vertebrate links: Xenbase ndufv1    NEW 
Molecular
reagents
All nucleic(270) cDNA(266) Primer pair(3) Other(1)
Microarray probesets(4)
Other database
links
VEGA Gene Model OTTMUSG00000034058 (Evidence)
Ensembl Gene Model ENSMUSG00000037916 (Evidence)
Entrez Gene 17995 (Evidence)
UniGene 29842
DFCI TC1779998, TC1728672, TC1573213
DoTS DT.496950, DT.110857629, DT.101190049
NIA Mouse Gene Index U019106
EC 1.6.5.3, 1.6.99.3
Consensus CDS Project CCDS29410.1
International Mouse Phenotyping Consortium Status Ndufv1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000034058 VEGA Gene Model | MGI Sequence Detail 5310 C57BL/6J ±  kb
transcript OTTMUST00000086022 VEGA | MGI Sequence Detail 1661 Not Applicable 
polypeptide OTTMUSP00000046526 VEGA | MGI Sequence Detail 464 Not Applicable 

For the selected sequences
All sequences(84) RefSeq(2) UniProt(6)
Polymorphisms
SNPs within 2kb(32 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR011538 NADH:ubiquinone oxidoreductase, 51kDa subunit
InterPro IPR001949 NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site
InterPro IPR011537 NADH ubiquinone oxidoreductase, F subunit
InterPro IPR019575 NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding
InterPro IPR019554 Soluble ligand binding domain
Protein Ontology PR:000011104 NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial
References
(Earliest) J:44483 Brady KP, et al., Genetic mapping of 262 loci derived from expressed sequences in a murine interspecific cross using single-strand conformational polymorphism analysis. Genome Res. 1997 Nov;7(11):1085-93
(Latest) J:204025 Hatle KM, et al., MCJ/DnaJC15, an endogenous mitochondrial repressor of the respiratory chain that controls metabolic alterations. Mol Cell Biol. 2013 Jun;33(11):2302-14
All references(42)
Other
accession IDs
MGD-MRK-36428

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
06/30/2015
MGI 5.22
The Jackson Laboratory