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Uqcrq
Gene Detail
Symbol

Name
ID
Uqcrq
ubiquinol-cytochrome c reductase, complex III subunit VII
MGI:107807
Synonyms
1100001F06Rik, 1500040F11Rik, 5830407L17Rik, c1502, Qpc, QP-C
Feature Type
protein coding gene
Genetic Map
Chromosome 11
31.94 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr11:53427922-53430831 bp, - strand
From VEGA annotation of GRCm38

  2910 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:40942  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 2 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: UQCRQ
Gene Tree: Uqcrq

Human
homologs
UQCRQ, ubiquinol-cytochrome c reductase, complex III subunit VII, 9.5kDa
Orthology source: HomoloGene, HGNC

IDs:
NCBI Gene ID: 27089
neXtProt AC: NX_O14949

Human Synonyms: MC3DN4, QCR8, QPC, QP-C, UQCR7

Human Chr (Location): 5q31.1; chr5:132866627-132868844 (+)  GRCh38.p2

Disease Associations: (1) Diseases Associated with Human UQCRQ

Mutations,
alleles, and
phenotypes
All mutations/alleles(31) : Gene trapped(28) Targeted(3)
Incidental mutations (data from CvDC )
Interactions
Uqcrq interacts with 120 markers (Mir17, Mir20b, Mir30a, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (8 annotations)
Process oxidation-reduction process, transport
Component membrane, mitochondrial inner membrane, ...
Function ubiquinol-cytochrome-c reductase activity
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (159)    Tissues (127)    Images (13)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 139
RT-PCR 20
cDNA source data(262)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase uqcrq    NEW 
Molecular
reagents
All nucleic(267) cDNA(264) Primer pair(2) Other(1)
Microarray probesets(6)
Other database
links
VEGA Gene Model OTTMUSG00000000054 (Evidence)
Ensembl Gene Model ENSMUSG00000044894 (Evidence)
Entrez Gene 22272 (Evidence)
UniGene 251621
DFCI TC1674200, TC1586861, TC1572069
DoTS DT.101373560, DT.101707815, DT.101267019, DT.97372448, DT.55153678, DT.103569670, DT.99868354
NIA Mouse Gene Index U032760
Consensus CDS Project CCDS36151.1
International Mouse Phenotyping Consortium Status Uqcrq
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000000054 VEGA Gene Model | MGI Sequence Detail 2910 C57BL/6J ±  kb
transcript OTTMUST00000012529 VEGA | MGI Sequence Detail 1521 Not Applicable 
polypeptide OTTMUSP00000005808 VEGA | MGI Sequence Detail 82 Not Applicable 

For the selected sequences
All sequences(51) RefSeq(4) UniProt(2)
Polymorphisms
SNPs within 2kb(85 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR004205 Cytochrome b-c1 complex subunit 8
Protein Ontology PR:000017129 cytochrome b-c1 complex subunit 8
References
(Earliest) J:44483 Brady KP, et al., Genetic mapping of 262 loci derived from expressed sequences in a murine interspecific cross using single-strand conformational polymorphism analysis. Genome Res. 1997 Nov;7(11):1085-93
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(45)
Other
accession IDs
MGD-MRK-36384, MGI:1913349, MGI:1915190, MGI:1923247, MGI:2138135

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
06/30/2015
MGI 5.22
The Jackson Laboratory