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Tuba1b Gene Detail
Summary
  • Symbol
    Tuba1b
  • Name
    tubulin, alpha 1B
  • Synonyms
    Tuba2
  • Feature Type
    protein coding gene
  • IDs
    MGI:107804
    NCBI Gene: 22143
  • Gene Overview
    MyGene.info: TUBA1B
Location & Maps
more
  • Sequence Map
    Chr15:98931425-98934565 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      3141 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 15, 55.21 cM
  • Mapping Data
    3 experiments
Homology
more
  • Human Ortholog
    TUBA1B, tubulin alpha 1b
  • Vertebrate Orthologs
    9
  • Human Ortholog
    TUBA1B, tubulin alpha 1b
    Orthology source: HomoloGene, HGNC
  • Synonyms
    K-ALPHA-1
  • Links
    NCBI Gene ID: 10376
    neXtProt AC: NX_P68363

  • Chr Location
    12q13.12; chr12:49127782-49131521 (-)  GRCh38.p2

Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    23 phenotype references
  • All Mutations and Alleles
    13
  • Chemically induced (other)
    1
  • Gene trapped
    8
  • Radiation induced
    2
  • Targeted
    2
  • Genomic Mutations
    3 involving Tuba1b
  • Incidental Mutations
    APF
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000017052 VEGA Gene Model | MGI Sequence Detail 3141 C57BL/6J ±  kb
transcript OTTMUST00000041303 VEGA | MGI Sequence Detail 1743 Not Applicable  
polypeptide OTTMUSP00000018538 VEGA | MGI Sequence Detail 451 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    5 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 24
    cDNA 23
    Primer pair 1

    Microarray probesets 5
Other
Accession IDs
less
MGD-MRK-36381
References
more
  • Summaries
    All 36
    Developmental Gene Expression 4
    Diseases 1
    Gene Ontology 8
    Phenotypes 23
  • Earliest
    J:19085 Lewis SA, et al., Five mouse tubulin isotypes and their regulated expression during development. J Cell Biol. 1985 Sep;101(3):852-61
  • Latest
    J:170947 Watanabe A, et al., Raftlin Is Involved in the Nucleocapture Complex to Induce Poly(I:C)-mediated TLR3 Activation. J Biol Chem. 2011 Mar 25;286(12):10702-11

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/27/2016
MGI 6.05
The Jackson Laboratory