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Atp5b Gene Detail
Summary
  • Symbol
    Atp5b
  • Name
    ATP synthase, H+ transporting mitochondrial F1 complex, beta subunit
  • Feature Type
    protein coding gene
  • IDs
    MGI:107801
    NCBI Gene: 11947
  • Gene Overview
    MyGene.info: ATP5F1B
  • Alliance
  • Transcription Start Sites
    13 TSS
Location &
Maps
more
  • Sequence Map
    Chr10:128083307-128090388 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 10, 76.39 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    56 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_107801
protein coding gene Chr10:128083273-128090391 (.)
129S1/SvImJ MGP_129S1SvImJ_G0017847
protein coding gene Chr10:131758823-131766995 (+)
A/J MGP_AJ_G0017822
protein coding gene Chr10:126486771-126493889 (+)
AKR/J MGP_AKRJ_G0017785
protein coding gene Chr10:130217932-130225068 (+)
BALB/cJ MGP_BALBcJ_G0017786
protein coding gene Chr10:126870612-126878682 (+)
C3H/HeJ MGP_C3HHeJ_G0017609
protein coding gene Chr10:130371366-130379192 (+)
C57BL/6NJ MGP_C57BL6NJ_G0018241
protein coding gene Chr10:136244265-136251273 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0015919
protein coding gene Chr10:120451080-120457779 (+)
CAST/EiJ MGP_CASTEiJ_G0017170
protein coding gene Chr10:131073610-131080534 (+)
CBA/J MGP_CBAJ_G0017579
protein coding gene Chr10:141753971-141777104 (+)
DBA/2J MGP_DBA2J_G0017685
protein coding gene Chr10:125560898-125568320 (+)
FVB/NJ MGP_FVBNJ_G0017680
protein coding gene Chr10:124495252-124502290 (+)
LP/J MGP_LPJ_G0017759
protein coding gene Chr10:132374849-132381975 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0017708
protein coding gene Chr10:144361206-144368324 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0018281
protein coding gene Chr10:130301530-130309011 (+)
PWK/PhJ MGP_PWKPhJ_G0016955
protein coding gene Chr10:125811245-125818345 (+)
SPRET/EiJ MGP_SPRETEiJ_G0016744
protein coding gene Chr10:129385313-129392283 (+)
WSB/EiJ MGP_WSBEiJ_G0017229
protein coding gene Chr10:130517806-130525475 (+)



Homology
more
  • Human Ortholog
    ATP5F1B, ATP synthase F1 subunit beta
  • Vertebrate Orthologs
    10
  • Human Ortholog
    ATP5F1B, ATP synthase F1 subunit beta
    Orthology source: HomoloGene, HGNC
  • Synonyms
    ATP5B, ATPMB, ATPSB, HEL-S-271
  • Links
    NCBI Gene ID: 506
    neXtProt AC: NX_P06576
    UniProt: P06576

  • Chr Location
    12q13.3; chr12:56638175-56646068 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    4 phenotypes from 1 allele in 1 genetic background
    11 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 11947 NCBI Gene Model | MGI Sequence Detail 7082 C57BL/6J ±  kb
    transcript NM_016774 RefSeq | MGI Sequence Detail 1879 C57BL/6  
    polypeptide P56480 UniProt | EBI | MGI Sequence Detail 529 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      1 Sequence
    • Protein Ontology
      PR:000004454 ATP synthase subunit beta, mitochondrial
    • EC
    • InterPro Domains
      IPR003593 AAA+ ATPase domain
      IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site
      IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain
      IPR036121 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain superfamily
      IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain
      IPR024034 ATPase, F1/V1 complex, beta/alpha subunit, C-terminal
      IPR005722 ATP synthase, F1 complex, beta subunit
      IPR027417 P-loop containing nucleoside triphosphate hydrolase
    Molecular
    Reagents
    less
    • All nucleic 1611
      cDNA 1609
      Primer pair 2

      Microarray probesets 2
    Other
    Accession IDs
    less
    MGD-MRK-36378
    References
    more
    • Summaries
      All 60
      Developmental Gene Expression 8
      Gene Ontology 13
      Phenotypes 11
    • Earliest
      J:44483 Brady KP, et al., Genetic mapping of 262 loci derived from expressed sequences in a murine interspecific cross using single-strand conformational polymorphism analysis. Genome Res. 1997 Nov;7(11):1085-93
    • Latest
      J:260356 Aiello FB, et al., IL-7-induced phosphorylation of the adaptor Crk-like and other targets. Cell Signal. 2018 Jul;47:131-141

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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    last database update
    11/06/2018
    MGI 6.13
    The Jackson Laboratory