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Hnrnpc
Gene Detail
Symbol

Name
ID
Hnrnpc
heterogeneous nuclear ribonucleoprotein C
MGI:107795
Synonyms
D14Wsu171e, hnRNPC1, hnRNP C1, hnRNPC2, hnRNP C2, Hnrpc, Hnrpc1, Hnrpc2
Feature Type
protein coding gene
Genetic Map
Chromosome 14
26.79 cM
Detailed Genetic Map ± 1 cM


Mapping data(8)
Sequence Map
Chr14:52073380-52104028 bp, - strand
From NCBI annotation of GRCm38

  30649 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:74524  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 2 dog

Protein SuperFamily: heterogeneous nuclear ribonucleoprotein C, Raly type
Gene Tree: Hnrnpc

Human
homologs
Human Homolog HNRNPC, heterogeneous nuclear ribonucleoprotein C (C1/C2)
NCBI Gene ID 3183
neXtProt AC  NX_P07910
Human Synonyms  C1, C2, HNRNP, HNRPC, SNRPC
Human Chr (Location)  14q11.2; chr14:21209136-21269479 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(157) : Gene trapped(153) Targeted(4)
Incidental mutations (data from Mutagenetix , APF )
 
Disruption of this gene results in embryonic lethality.
 
Interactions
Hnrnpc interacts with 275 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (28 annotations)
Process 3'-UTR-mediated mRNA stabilization, ATP-dependent chromatin remodeling, ...
Component catalytic step 2 spliceosome, cytosol, ...
Function identical protein binding, mRNA 3'-UTR binding, ...
External Resources: FuncBase
Expression
Literature Summary: (5 records)
Data Summary: Results (30)    Tissues (26)    Images (3)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 22
RT-PCR 8
cDNA source data(21)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(27) cDNA(24) Primer pair(3)
Microarray probesets(4)
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 15381 NCBI Gene Model | MGI Sequence Detail 30649 C57BL/6J ±  kb
transcript NM_016884 RefSeq | MGI Sequence Detail 2844 C57BL/6 
polypeptide Q9Z204 UniProt | EBI | MGI Sequence Detail 313 Not Applicable 

For the selected sequences
All sequences(105) RefSeq(32) UniProt(3)
Polymorphisms
SNPs within 2kb(323 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR017347 Heterogeneous nuclear ribonucleoprotein C, Raly
InterPro IPR012677 Nucleotide-binding, alpha-beta plait
InterPro IPR000504 RNA recognition motif domain
Protein Ontology PR:000008662 heterogeneous nuclear ribonucleoproteins C1/C2
Graphical View of Protein Domain Structure
References
(Earliest) J:151685 von Melchner H, et al., Selective disruption of genes expressed in totipotent embryonal stem cells. Genes Dev. 1992 Jun;6(6):919-27
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(47)
Other
accession IDs
MGD-MRK-28111, MGD-MRK-28112, MGD-MRK-36372, MGD-MRK-36437, MGI:104817, MGI:104818, MGI:107860, MGI:2146114

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory