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Hnrnpc Gene Detail
Summary
  • Symbol
    Hnrnpc
  • Name
    heterogeneous nuclear ribonucleoprotein C
  • Synonyms
    D14Wsu171e, hnRNPC1, hnRNP C1, hnRNPC2, hnRNP C2, Hnrpc, Hnrpc1, Hnrpc2
  • Feature Type
    protein coding gene
  • IDs
    MGI:107795
    NCBI Gene: 15381
  • Gene Overview
    MyGene.info: HNRNPC
Location & Maps
more
  • Sequence Map
    Chr14:52073380-52104028 bp, - strand
  • From NCBI annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      30649 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 14, 26.79 cM
  • Mapping Data
    8 experiments
Homology
more
  • Human Ortholog
    HNRNPC, heterogeneous nuclear ribonucleoprotein C (C1/C2)
  • Vertebrate Orthologs
    8
  • Human Ortholog
    HNRNPC, heterogeneous nuclear ribonucleoprotein C (C1/C2)
    Orthology source: HomoloGene, HGNC
  • Synonyms
    C1, C2, HNRNP, HNRPC, SNRPC
  • Links
    NCBI Gene ID: 3183
    neXtProt AC: NX_P07910

  • Chr Location
    14q11.2; chr14:21209136-21269479 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    4 phenotypes from 2 alleles in 1 genetic background
    13 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    159
  • Chemically induced (other)
    1
  • Gene trapped
    153
  • Targeted
    5
  • Genomic Mutations
    1 involving Hnrnpc
  • Incidental Mutations
Mice homozygous for a gene trapped allele fail to undergo gastrulation, appear to arrest at the egg cylinder stage, and are resorbed at various times thereafter.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 15381 NCBI Gene Model | MGI Sequence Detail 30649 C57BL/6J ±  kb
transcript NM_016884 RefSeq | MGI Sequence Detail 2844 C57BL/6  
polypeptide Q9Z204 UniProt | EBI | MGI Sequence Detail 313 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    319 from dbSNP Build 142
Protein
Information
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  • UniProt
    2 Sequences
  • Protein Ontology
    PR:000008662 heterogeneous nuclear ribonucleoproteins C1/C2
  • InterPro Domains
    IPR017347 Heterogeneous nuclear ribonucleoprotein C
    IPR012677 Nucleotide-binding alpha-beta plait domain
    IPR000504 RNA recognition motif domain
Molecular
Reagents
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  • All nucleic 27
    cDNA 24
    Primer pair 3

    Microarray probesets 4
Other
Accession IDs
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MGD-MRK-28111, MGD-MRK-28112, MGD-MRK-36372, MGD-MRK-36437, MGI:104817, MGI:104818, MGI:107860, MGI:2146114
References
more
  • Summaries
    All 44
    Developmental Gene Expression 5
    Gene Ontology 7
    Phenotypes 13
  • Earliest
    J:151685 von Melchner H, et al., Selective disruption of genes expressed in totipotent embryonal stem cells. Genes Dev. 1992 Jun;6(6):919-27
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/20/2016
MGI 6.05
The Jackson Laboratory