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Hnrnpc
Gene Detail
 Symbol
Name
ID
Hnrnpc
heterogeneous nuclear ribonucleoprotein C
MGI:107795
Synonyms D14Wsu171e, hnRNPC1, hnRNP C1, hnRNPC2, hnRNP C2, Hnrpc, Hnrpc1, Hnrpc2
Feature Type protein coding gene
Genetic Map
Chromosome 14
26.79 cM
Detailed Genetic Map ± 1 cM


Mapping data(8)
Sequence Map
Chr14:52073380-52104028 bp, - strand
From NCBI annotation of GRCm38

  30649 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:74524  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 2 dog

Protein SuperFamily: heterogeneous nuclear ribonucleoprotein C, Raly type
Gene Tree: Hnrnpc

Human
homologs
Human Homolog HNRNPC, heterogeneous nuclear ribonucleoprotein C (C1/C2)
NCBI Gene ID 3183
neXtProt AC  NX_P07910
Human Synonyms  C1, C2, HNRNP, HNRPC, SNRPC
Human Chr (Location)  14q11.2; chr14:21209136-21269479 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(157) : Gene trapped(153) Targeted(4)
Incidental mutations (data from Mutagenetix , APF )
 
Disruption of this gene results in embryonic lethality.
 
Interactions
Hnrnpc interacts with 275 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (27 annotations)
Process 3'-UTR-mediated mRNA stabilization, ATP-dependent chromatin remodeling, ...
Component catalytic step 2 spliceosome, cytosol, ...
Function identical protein binding, mRNA 3'-UTR binding, ...
External Resources: FuncBase
Expression
Literature Summary: (5 records)
Data Summary: Results (30)    Tissues (26)    Images (3)
Theiler Stages: 11, 21, 27
Assay TypeResults
RNA in situ 22
RT-PCR 8
cDNA source data(21)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(27) cDNA(24) Primer pair(3)
Microarray probesets(4)
Other database
links
Ensembl Gene ModelENSMUSG00000060373 (Evidence)
Entrez Gene15381 (Evidence)
DFCITC1573891, TC1580945, TC1581238, TC1585314, TC1590573, TC1640407, TC1675776
DoTSDT.101200899, DT.101404970, DT.101404971, DT.101739411, DT.102558141, DT.103577511, DT.103589667, DT.103589668, DT.103589669, DT.110772863, DT.55107862, DT.94400600, DT.97387368, DT.97387371, DT.97387375, DT.97387376, DT.99865590
NIA Mouse Gene IndexU035533, U064375
Consensus CDS ProjectCCDS36917.1
International Mouse Knockout Project StatusHnrnpc
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 15381 NCBI Gene Model | MGI Sequence Detail 30649 C57BL/6J ±  kb
transcript NM_016884 RefSeq | MGI Sequence Detail 2844 C57BL/6 
polypeptide Q9Z204 UniProt | EBI | MGI Sequence Detail 313 Not Applicable 

For the selected sequences
All sequences(104) RefSeq(32) UniProt(2)
Polymorphisms SNPs within 2kb(323 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR017347 Heterogeneous nuclear ribonucleoprotein C, Raly
InterPro IPR012677 Nucleotide-binding, alpha-beta plait
InterPro IPR000504 RNA recognition motif domain
Protein Ontology PR:000008662 heterogeneous nuclear ribonucleoproteins C1/C2
Graphical View of Protein Domain Structure
References (Earliest) J:151685 von Melchner H, et al., Selective disruption of genes expressed in totipotent embryonal stem cells. Genes Dev. 1992 Jun;6(6):919-27
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(47)
Other
accession IDs
MGD-MRK-28111, MGD-MRK-28112, MGD-MRK-36372, MGD-MRK-36437, MGI:104817, MGI:104818, MGI:107860, MGI:2146114

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory