Zfp65 MGI Mouse Gene Detail - MGI:107769

Symbol

Zfp65
Name

zinc finger protein 65
Synonyms

KRAB5, Zfp71-rs1

Feature Type

protein coding gene
IDs

MGI:107769
NCBI Gene: 235907
Alliance

gene page
Transcription Start Sites

2 TSS

Sequence Map

Chr13:67853428-67877238 bp, - strand
From NCBI annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 13, 34.70 cM
Mapping Data

1 experiment

SNPs within 2kb

177 from dbSNP Build 142
Strain Annotations

17
RFLP

1

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_107769	protein coding gene	Chr13:67853428-67877292 (-)
129S1/SvImJ	MGP_129S1SvImJ_G0020719	protein coding gene	Chr13:67869493-67896670 (-)
A/J	MGP_AJ_G0020675	protein coding gene	Chr13:65456509-65473942 (-)
AKR/J	MGP_AKRJ_G0020650	protein coding gene	Chr13:67629620-67656855 (-)
BALB/cJ	MGP_BALBcJ_G0020673	protein coding gene	Chr13:65946250-65962292 (-)
C3H/HeJ	MGP_C3HHeJ_G0020467	protein coding gene	Chr13:67244278-67261673 (-)
C57BL/6NJ	MGP_C57BL6NJ_G0021109	protein coding gene	Chr13:70290566-70323777 (-)
CAROLI/EiJ	MGP_CAROLIEiJ_G0018680	protein coding gene	Chr13:62928697-62973175 (-)
CAST/EiJ	MGP_CASTEiJ_G0019985	protein coding gene	Chr13:66460183-66479629 (-)
CBA/J	MGP_CBAJ_G0020425	protein coding gene	Chr13:72825267-72845870 (-)
DBA/2J	MGP_DBA2J_G0020551	protein coding gene	Chr13:65335134-65354076 (-)
FVB/NJ	no annotation
LP/J	MGP_LPJ_G0020624	protein coding gene	Chr13:68155684-68174800 (-)
NOD/ShiLtJ	MGP_NODShiLtJ_G0020559	protein coding gene	Chr13:71651167-71673317 (-)
NZO/HlLtJ	MGP_NZOHlLtJ_G0021149	protein coding gene	Chr13:66870293-66889382 (-)
PWK/PhJ	MGP_PWKPhJ_G0019739	protein coding gene	Chr13:64190650-64233604 (-)
SPRET/EiJ	MGP_SPRETEiJ_G0019564	protein coding gene	Chr13:63912486-63932979 (-)
WSB/EiJ	MGP_WSBEiJ_G0020044	protein coding gene	Chr13:67382035-67396879 (-)

Human Ortholog

ZNF253, zinc finger protein 253

Vertebrate Orthologs

1

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

ZNF253, zinc finger protein 253
Synonyms

BMZF1, BMZF-1, ZNF411
Links

HGNC:13497

NCBI Gene ID: 56242

neXtProt AC: NX_O75346

UniProt: O75346
Chr Location

19p13.11; chr19:19865830-19894674 (+) GRCh38

MGI Vertebrate Homology

Zfp65 stringent orthology
1 human;1 mouse
HCOP

vertebrate homology predictions: ZNF253
Gene Tree

Zfp65

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Phenotype Summary

8 phenotype references

All Mutations and Alleles

6
Chemically induced (other)

1
Gene trapped

5
Genomic Mutations

1 involving Zfp65
Find Mice (IMSR)

19 strains or lines available

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All GO Annotations

4
GO References

1

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	non-membrane-bounded organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

782
Tissues

55
cDNA Data

26
Literature Summary

3

Images

Tissue x Stage Matrix

Other Mouse Links

Allen Institute

GEO

Expression Atlas

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All Sequences

51
RefSeq

12
UniProt

6
CCDS

CCDS49303.1

Ensembl

ENSMUSG00000071281 (Evidence)
NCBI Gene

235907

			Length	Strain/Species	Flank
genomic	235907	NCBI Gene Model \| MGI Sequence Detail	23811	C57BL/6J	± kb
transcript	NM_001402906	RefSeq \| MGI Sequence Detail	4088	ZRU/MplStud
polypeptide	NP_001389832	RefSeq \| MGI Sequence Detail	400	ZRU/MplStud

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UniProt

6 Sequences
InterPro Domains

IPR036051 KRAB domain superfamily

IPR001909 Krueppel-associated box

IPR036236 Zinc finger C2H2 superfamily

IPR013087 Zinc finger C2H2-type

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All nucleic 27

cDNA 26

Primer pair 1

Microarray probesets 3

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MGD-MRK-36346

Summaries

All 29

Developmental Gene Expression 3

Gene Ontology 1

Phenotypes 8
Earliest

J:182573 Roderick TH, Producing and detecting paracentric chromosomal inversions in mice. Mutat Res. 1971 Jan;11(1):59-69
Latest

J:140465 Guo G, et al., Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst. Dev Cell. 2010 Apr 20;18(4):675-85

TSS for Zfp65:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr123115	Chr13:67877228-67877264 (-)	-8 bp
Tssr123114	Chr13:67872383-67872459 (-)	4,817 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/16/2024 MGI 6.23