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Neurog1
Gene Detail
Symbol

Name
ID
Neurog1
neurogenin 1
MGI:107754
Synonyms
bHLHa6, Math4C, Neurod3, neurogenin, neurogenin 1, ngn1
Feature Type
protein coding gene
Genetic Map
Chromosome 13
30.06 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr13:56250505-56252163 bp, - strand
From Ensembl annotation of GRCm38

  1659 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:4490  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: Neurog1

Human
homologs
Human Homolog NEUROG1, neurogenin 1
NCBI Gene ID 4762
neXtProt AC  NX_Q92886
Human Synonyms  AKA, bHLHa6, Math4C, NEUROD3, ngn1
Human Chr (Location)  5q23-q31; chr5:135534282-135535949 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(3) : Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
 
Homozygotes for a targeted null mutation exhibit defects in midbrain, dorsal root sensory ganglia and a subset of cranial ganglia. Mutants are born alive, but fail to nurse, and die within 12 hours.
 
Interactions
Neurog1 interacts with 178 markers (Mir9-1, Mir9-2, Mir9-3, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (24 annotations)
Process cell differentiation, cell fate commitment, ...
Component neuronal cell body, nucleus, ...
Function chromatin binding, DNA binding, ...
External Resources: FuncBase
Expression
Literature Summary: (155 records)
Data Summary: Results (400)    Tissues (213)    Images (86)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 380
Northern blot 11
Western blot 1
RT-PCR 8
cDNA source data(12)
External Resources: Allen Institute   GENSAT   GEO   Expression Atlas
Molecular
reagents
All nucleic(33) Genomic(6) cDNA(15) Primer pair(7) Other(5)
Microarray probesets(3)
Other database
links
Ensembl Gene ModelENSMUSG00000048904 (Evidence)
Entrez Gene18014 (Evidence)
UniGene266665
DFCITC1586769
DoTSDT.40168057
NIA Mouse Gene IndexU034830
Consensus CDS ProjectCCDS26559.1
International Mouse Knockout Project StatusNeurog1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000048904 Ensembl Gene Model | MGI Sequence Detail 1659 C57BL/6J ±  kb
transcript ENSMUST00000058475 Ensembl | MGI Sequence Detail 1659 Not Applicable 
polypeptide ENSMUSP00000050484 Ensembl | MGI Sequence Detail 244 Not Applicable 

For the selected sequences
All sequences(14) RefSeq(2) UniProt(1)
Polymorphisms
RFLP(1) : SNPs within 2kb(7 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR011598 Myc-type, basic helix-loop-helix (bHLH) domain
Protein Ontology PR:000011156 neurogenin-1
References
(Earliest) J:35346 McCormick MB, et al., NeuroD2 and neuroD3: distinct expression patterns and transcriptional activation potentials within the neuroD gene family. Mol Cell Biol. 1996 Oct;16(10):5792-800
(Latest) J:215487 Thompson CL, et al., A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain. Neuron. 2014 Jul 16;83(2):309-23
All references(206)
Other
accession IDs
MGD-MRK-36330

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/16/2014
MGI 5.20
The Jackson Laboratory