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Myo1b Gene Detail
Summary
  • Symbol
    Myo1b
  • Name
    myosin IB
  • Feature Type
    protein coding gene
  • IDs
    MGI:107752
    NCBI Gene: 17912
  • Gene Overview
    MyGene.info: MYO1B
Location & Maps
more
  • Sequence Map
    Chr1:51749765-51916071 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      166307 bp   ±  kb flank

  • Genome Browsers
Homology
more
  • Human Ortholog
    MYO1B, myosin IB
  • Vertebrate Orthologs
    9
  • Human Ortholog
    MYO1B, myosin IB
    Orthology source: HGNC, HomoloGene
  • Synonyms
    myr1
  • Links
    NCBI Gene ID: 4430
    neXtProt AC: NX_O43795

  • Chr Location
    2q12-q34; chr2:191245185-191425389 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    9 phenotype references
  • All Mutations and Alleles
    33
  • Chemically induced (other)
    1
  • Gene trapped
    31
  • Radiation induced
    1
  • Genomic Mutations
    2 involving Myo1b
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000016470 VEGA Gene Model | MGI Sequence Detail 166307 C57BL/6J ±  kb
transcript OTTMUST00000039700 VEGA | MGI Sequence Detail 4767 Not Applicable  
polypeptide OTTMUSP00000017715 VEGA | MGI Sequence Detail 1136 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    1800 from dbSNP Build 142
  • RFLP
Protein
Information
less
  • UniProt
    9 Sequences
  • Protein Ontology
    PR:000010856 myosin-Ib
  • InterPro Domains
    IPR010926 Class I myosin tail homology domain
    IPR000048 IQ motif, EF-hand binding site
    IPR001609 Myosin head, motor domain
    IPR027417 P-loop containing nucleoside triphosphate hydrolase
Molecular
Reagents
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  • All nucleic 17
    cDNA 17

    Microarray probesets 8
Other
Accession IDs
less
MGD-MRK-36328, MGI:2138072
References
more
  • Summaries
    All 31
    Developmental Gene Expression 3
    Gene Ontology 5
    Phenotypes 9
  • Earliest
    J:4139 Sherr EH, et al., Mammalian myosin I alpha, I beta, and I gamma: new widely expressed genes of the myosin I family. J Cell Biol. 1993 Mar;120(6):1405-16
  • Latest
    J:226997 Bebee TW, et al., The splicing regulators Esrp1 and Esrp2 direct an epithelial splicing program essential for mammalian development. Elife. 2015;4

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
05/17/2016
MGI 6.03
The Jackson Laboratory