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Myo1b Gene Detail
Summary
  • Symbol
    Myo1b
  • Name
    myosin IB
  • Feature Type
    protein coding gene
  • IDs
    MGI:107752
    NCBI Gene: 17912
  • Alliance
    genome feature page
  • Transcription Start Sites
    8 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:51788915-51955143 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 1, 26.58 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    5557 from dbSNP Build 142
  • Strain Annotations
    19
  • RFLP
    1
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_107752
 protein coding gene Chr1:51788915-51955230 (-)
129S1/SvImJ ENSMUSG00200001919
 protein coding gene Chr1:49265286-49428893 (-)
A/J ENSMUSG00195001858
 protein coding gene Chr1:49160160-49326497 (-)
AKR/J ENSMUSG00220003484
 protein coding gene Chr1:48922773-49086128 (-)
BALB/cJ ENSMUSG00180003021
 protein coding gene Chr1:49098357-49261713 (-)
C3H/HeJ ENSMUSG00175000102
 protein coding gene Chr1:49189690-49356018 (-)
C57BL/6NJ ENSMUSG00215002884
 protein coding gene Chr1:49116885-49283209 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0014130
 protein coding gene Chr1:42158435-42339847 (+)
CAST/EiJ ENSTCUG00005000853
 protein coding gene Chr1:49025312-49190030 (-)
CBA/J ENSMUSG00210027657
 protein coding gene Chr1:48894805-49061130 (-)
DBA/2J ENSMUSG00185028716
 protein coding gene Chr1:50014421-50180756 (-)
FVB/NJ ENSMUSG00205003094
 protein coding gene Chr1:48840081-49006420 (-)
JF1/MsJ ENSUMUG00000001255
 protein coding gene Chr1:48990145-49160375 (-)
LP/J ENSMUSG00230000982
 protein coding gene Chr1:50010982-50177276 (-)
NOD/ShiLtJ ENSMUSG00190002111
 protein coding gene Chr1:49028503-49192102 (-)
NZO/HlLtJ ENSMUSG00225008451
 protein coding gene Chr1:53186001-53352345 (-)
PWK/PhJ ENSLUMG00010002370
 protein coding gene Chr1:48533277-48696048 (-)
SPRET/EiJ ENSMSPG00010012300
 protein coding gene Chr1:50222643-50386875 (-)
WSB/EiJ ENSIUOG00005003340
 protein coding gene Chr1:48730011-48893887 (-)



Homology
more
  • Human Ortholog
    MYO1B, myosin IB
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MYO1B, myosin IB
  • Synonyms
    MMIa, MMI-alpha, MYH-1c, myr1
  • Links
    NCBI Gene ID: 4430
    UniProt: O43795

  • Chr Location
    2q32.3; chr2:191245064-191425820 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotypes from 1 allele in 1 genetic background
    13 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    65
  • GO References
    9
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    715
  • Tissues
    46
  • cDNA Data
    18
  • Literature Summary
    6
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 17912 NCBI Gene Model | MGI Sequence Detail 166229 C57BL/6J ±  kb
transcript NM_001420362 RefSeq | MGI Sequence Detail 5401 ZRU/MplStud  
polypeptide P46735 UniProt | EBI | MGI Sequence Detail 1107 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 20
    cDNA 18
    Primer pair 2

    Microarray probesets 8
Other
Accession IDs
less
MGD-MRK-36328, MGI:2138072
References
more
  • Summaries
    All 52
    Developmental Gene Expression 6
    Gene Ontology 9
    Phenotypes 13
  • Earliest
    J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
  • Latest
    J:380581 Cakir Z, et al., Quantitative Proteomic Analysis Reveals apoE4-Dependent Phosphorylation of the Actin-Regulating Protein VASP. Mol Cell Proteomics. 2023 May;22(5):100541
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory