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Dync1i2
Gene Detail
Symbol

Name
ID
Dync1i2
dynein cytoplasmic 1 intermediate chain 2
MGI:107750
Synonyms
3110079H08Rik, Dncic2
Feature Type
protein coding gene
Genetic Map
Chromosome 2
42.38 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr2:71211706-71263303 bp, + strand
From VEGA annotation of GRCm38

  51598 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:37921  Vertebrate Homology Class
1 mouse; 1 rat; 1 rhesus macaque; 1 dog; 1 western clawed frog; 2 zebrafish

Gene Tree: Dync1i2

Mutations,
alleles, and
phenotypes
All mutations/alleles(65) : Chemically induced (ENU)(1) Gene trapped(62) Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for an ENU-induced allele exhibit a trend towards slight locomotor deficit.
 
Interactions
Dync1i2 interacts with 149 markers (Mir7-1, Mir7b, Mir17, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (9 annotations)
Process microtubule-based movement, transport
Component cytoplasm, cytoplasmic dynein complex, ...
Function motor activity, protein complex binding
External Resources: FuncBase
Expression
Literature Summary: (7 records)
Data Summary: Results (88)    Tissues (57)    Images (17)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 79
Northern blot 9
cDNA source data(205)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(207) cDNA(206) Other(1)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000013157 (Evidence)
Ensembl Gene ModelENSMUSG00000027012 (Evidence)
Entrez Gene13427 (Evidence)
UniGene249479
DFCITC1571858, TC1735516
DoTSDT.101158315, DT.101158368, DT.101234191, DT.494644, DT.55214219, DT.91333448, DT.91398894, DT.99871342, DT.99871344
NIA Mouse Gene IndexU001891
Consensus CDS ProjectCCDS16112.1, CCDS57175.1
International Mouse Knockout Project StatusDync1i2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000013157 VEGA Gene Model | MGI Sequence Detail 51598 C57BL/6J ±  kb
transcript OTTMUST00000042241 VEGA | MGI Sequence Detail 2573 Not Applicable 
polypeptide OTTMUSP00000018982 VEGA | MGI Sequence Detail 638 Not Applicable 

For the selected sequences
All sequences(123) RefSeq(32) UniProt(11)
Polymorphisms
RFLP(1) : SNPs within 2kb(396 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR025956 Cytoplasmic dynein 1 intermediate chain 1/2
InterPro IPR001680 WD40 repeat
InterPro IPR017986 WD40-repeat-containing domain
InterPro IPR015943 WD40/YVTN repeat-like-containing domain
Protein Ontology PR:000006772 cytoplasmic dynein 1 intermediate chain 2
References
(Earliest) J:34934 Vaughan KT, et al., Multiple mouse chromosomal loci for dynein-based motility. Genomics. 1996 Aug 15;36(1):29-38
(Latest) J:193641 Nakano Y, et al., A mutation in the Srrm4 gene causes alternative splicing defects and deafness in the Bronx waltzer mouse. PLoS Genet. 2012;8(10):e1002966
All references(48)
Other
accession IDs
MGD-MRK-36326, MGI:1925763, MGI:2139394

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
10/08/2014
MGI 5.20
The Jackson Laboratory