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Dync1i1 Gene Detail
Summary
  • Symbol
    Dync1i1
  • Name
    dynein cytoplasmic 1 intermediate chain 1
  • Synonyms
    DIC, Dncic1, IC74
  • Feature Type
    protein coding gene
  • IDs
    MGI:107743
    NCBI Gene: 13426
  • Gene Overview
    MyGene.info: DYNC1I1
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr6:5725639-6028039 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 6, 2.26 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    969 from dbSNP Build 142
  • Strain Annotations
    18
  • RFLP
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_107743
protein coding gene Chr6:5725632-6028039 (.)
129S1/SvImJ MGP_129S1SvImJ_G0030437
protein coding gene Chr6:2588633-2905746 (+)
A/J MGP_AJ_G0030410
protein coding gene Chr6:2487195-2784918 (+)
AKR/J MGP_AKRJ_G0030337
protein coding gene Chr6:2553328-2857853 (+)
BALB/cJ MGP_BALBcJ_G0030419
protein coding gene Chr6:2453272-2754379 (+)
C3H/HeJ MGP_C3HHeJ_G0030133
protein coding gene Chr6:2533720-2845355 (+)
C57BL/6NJ MGP_C57BL6NJ_G0030874
protein coding gene Chr6:2645085-2968898 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0028085
protein coding gene Chr6:2156921-2462377 (+)
CAST/EiJ MGP_CASTEiJ_G0029534
protein coding gene Chr6:2522528-2838348 (+)
CBA/J MGP_CBAJ_G0030111
protein coding gene Chr6:2756613-3121280 (+)
DBA/2J MGP_DBA2J_G0030255
protein coding gene Chr6:2437780-2740393 (+)
FVB/NJ MGP_FVBNJ_G0030209
protein coding gene Chr6:2425267-2721753 (+)
LP/J MGP_LPJ_G0030342
protein coding gene Chr6:2535325-2849257 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0030245
protein coding gene Chr6:2807884-3138287 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0030904
protein coding gene Chr6:2509923-2822559 (+)
PWK/PhJ MGP_PWKPhJ_G0029249
protein coding gene Chr6:2384978-2686705 (+)
SPRET/EiJ MGP_SPRETEiJ_G0029085
protein coding gene Chr6:2557450-2876938 (+)
WSB/EiJ MGP_WSBEiJ_G0029611
protein coding gene Chr6:2504351-2823714 (+)



Homology
more
  • Human Ortholog
    DYNC1I1, dynein cytoplasmic 1 intermediate chain 1
  • Vertebrate Orthologs
    10
  • Human Ortholog
    DYNC1I1, dynein cytoplasmic 1 intermediate chain 1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    DNCI1, DNCIC1
  • Links
    NCBI Gene ID: 1780
    neXtProt AC: NX_O14576
    UniProt: O14576

  • Chr Location
    7q21.3; chr7:95772506-96110322 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000029757 Ensembl Gene Model | MGI Sequence Detail 302401 C57BL/6J ±  kb
transcript ENSMUST00000115555 Ensembl | MGI Sequence Detail 2669 Not Applicable  
polypeptide ENSMUSP00000111217 Ensembl | MGI Sequence Detail 645 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    7 Sequences
  • InterPro Domains
    IPR025956 Cytoplasmic dynein 1 intermediate chain 1/2
    IPR001680 WD40 repeat
    IPR017986 WD40-repeat-containing domain
    IPR036322 WD40-repeat-containing domain superfamily
    IPR015943 WD40/YVTN repeat-like-containing domain superfamily
Molecular
Reagents
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  • All nucleic 25
    cDNA 22
    Primer pair 2
    Other 1

    Microarray probesets 3
Other
Accession IDs
less
MGD-MRK-36319
References
more
  • Summaries
    All 57
    Developmental Gene Expression 15
    Gene Ontology 12
    Phenotypes 6
  • Earliest
    J:34934 Vaughan KT, et al., Multiple mouse chromosomal loci for dynein-based motility. Genomics. 1996 Aug 15;36(1):29-38
  • Latest
    J:258369 Inaba Y, et al., Transport of the outer dynein arm complex to cilia requires a cytoplasmic protein Lrrc6. Genes Cells. 2016 Jul;21(7):728-39

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/13/2018
MGI 6.13
The Jackson Laboratory