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Stra6
Gene Detail
 Symbol
Name
ID
Stra6
stimulated by retinoic acid gene 6
MGI:107742
Feature Type protein coding gene
Genetic Map
Chromosome 9
31.63 cM, cytoband C
Detailed Genetic Map ± 1 cM


Mapping data(4)
Sequence Map
Chr9:58063788-58153955 bp, + strand
From VEGA annotation of GRCm38

  90168 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:7554  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Stra6

Human
homologs
Human Homolog STRA6, stimulated by retinoic acid 6
NCBI Gene ID 64220
neXtProt AC  NX_Q9BX79
Human Synonyms  MCOPCB8, MCOPS9
Human Chr (Location)  15q24.1; chr15:74179466-74209705 (-)  GRCh38
Disease Associations  (1) Diseases Associated with Human STRA6
Mutations,
alleles, and
phenotypes
All mutations/alleles(20) : Gene trapped(15) Targeted(5)
Incidental mutations (data from Mutagenetix , APF )
 
Male mice homozygous for a gene trap allele exhibit growth retardation. Mice homozygous for a knock-out allele exhibit persistent hyperplastic primary vitreous, shorter inner and outer segment and reduced rod and cone function.
 
Interactions
Stra6 interacts with 115 markers (Mir1a-1, Mir1a-2, Mir22, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (45 annotations)
Process adrenal gland development, alveolar primary septum development, ...
Component integral component of membrane, membrane, ...
Function protein binding, receptor activity, ...
External Resources: FuncBase
Expression
Literature Summary: (10 records)
Data Summary: Results (158)    Tissues (60)    Images (38)
Theiler Stages: 11, 19, 20, 21, 22, 23, 25, 28
Assay TypeResults
RNA in situ 152
RT-PCR 6
cDNA source data(46)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(50) Genomic(1) cDNA(46) Primer pair(2) Other(1)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000024607 (Evidence)
Ensembl Gene ModelENSMUSG00000032327 (Evidence)
Entrez Gene20897 (Evidence)
UniGene10801
DFCITC1581999, TC1593971, TC1628670, TC1646454
DoTSDT.101213495, DT.101231730, DT.101736134, DT.526652, DT.91557940
NIA Mouse Gene IndexU010564
Consensus CDS ProjectCCDS23236.1
International Mouse Knockout Project StatusStra6
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000024607 VEGA Gene Model | MGI Sequence Detail 90168 C57BL/6J ±  kb
transcript OTTMUST00000060481 VEGA | MGI Sequence Detail 2725 Not Applicable 
polypeptide OTTMUSP00000029498 VEGA | MGI Sequence Detail 670 Not Applicable 

For the selected sequences
All sequences(104) RefSeq(20) UniProt(11)
Polymorphisms SNPs within 2kb(476 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR026612 Stimulated by retinoic acid gene 6 protein
Protein Ontology PR:000015772 stimulated by retinoic acid gene 6 protein
References (Earliest) J:28316 Bouillet P, et al., Efficient cloning of cDNAs of retinoic acid-responsive genes in P19 embryonal carcinoma cells and characterization of a novel mouse gene, Stra1 (mouse LERK-2/Eplg2). Dev Biol. 1995 Aug;170(2):420-33
(Latest) J:210500 Alapatt P, et al., Liver retinol transporter and receptor for serum retinol-binding protein (RBP4). J Biol Chem. 2013 Jan 11;288(2):1250-65
All references(47)
Other
accession IDs
MGD-MRK-36318, MGI:2143166

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/23/2014
MGI 5.19
The Jackson Laboratory