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Dnah2 Gene Detail
Summary
  • Symbol
    Dnah2
  • Name
    dynein, axonemal, heavy chain 2
  • Synonyms
    2900022L05Rik, D330014H01Rik, Dnahc2, Dnhd3
  • Feature Type
    protein coding gene
  • IDs
    MGI:107731
    NCBI Gene: 327954
  • Alliance
Location &
Maps
more
  • Sequence Map
    Chr11:69420807-69549108 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 11, 42.63 cM, cytoband B4
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1124 from dbSNP Build 142
  • Strain Annotations
    18
  • RFLP
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_107731
protein coding gene Chr11:69420807-69549110 (-)
129S1/SvImJ MGP_129S1SvImJ_G0018535
protein coding gene Chr11:69851040-69995049 (-)
A/J MGP_AJ_G0018503
protein coding gene Chr11:67222905-67360883 (-)
AKR/J MGP_AKRJ_G0018472
protein coding gene Chr11:69234686-69369212 (-)
BALB/cJ MGP_BALBcJ_G0018475
protein coding gene Chr11:67542619-67672649 (-)
C3H/HeJ MGP_C3HHeJ_G0018288
protein coding gene Chr11:69252757-69391781 (-)
C57BL/6NJ MGP_C57BL6NJ_G0018926
protein coding gene Chr11:71966557-72115894 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0016571
protein coding gene Chr11:64150886-64284196 (-)
CAST/EiJ MGP_CASTEiJ_G0017843
protein coding gene Chr11:69487705-69635383 (-)
CBA/J MGP_CBAJ_G0018261
protein coding gene Chr11:75190228-75338876 (-)
DBA/2J MGP_DBA2J_G0018370
protein coding gene Chr11:66812261-66943866 (-)
FVB/NJ MGP_FVBNJ_G0018360
protein coding gene Chr11:66441513-66580844 (-)
LP/J MGP_LPJ_G0018440
protein coding gene Chr11:70423908-70565266 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0018383
protein coding gene Chr11:75802160-75942185 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0018968
protein coding gene Chr11:69483694-69624869 (-)
PWK/PhJ MGP_PWKPhJ_G0017617
protein coding gene Chr11:67457373-67591525 (-)
SPRET/EiJ MGP_SPRETEiJ_G0017407
protein coding gene Chr11:69303273-69442439 (-)
WSB/EiJ MGP_WSBEiJ_G0017897
protein coding gene Chr11:69163667-69299157 (-)



Homology
more
  • Human Ortholog
    DNAH2, dynein axonemal heavy chain 2
  • Vertebrate Orthologs
    9
  • Human Ortholog
    DNAH2, dynein axonemal heavy chain 2
    Orthology source: HGNC, HomoloGene
  • Synonyms
    DNAHC2, DNHD3
  • Links
    NCBI Gene ID: 146754
    neXtProt AC: NX_Q9P225
    UniProt: Q9P225

  • Chr Location
    17p13.1; chr17:7717354-7833744 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    9 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 327954 NCBI Gene Model | MGI Sequence Detail 128302 C57BL/6J ±  kb
transcript NM_001081330 RefSeq | MGI Sequence Detail 13704 Not Specified  
polypeptide P0C6F1 UniProt | EBI | MGI Sequence Detail 4456 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    3 Sequences
  • InterPro Domains
    IPR003593 AAA+ ATPase domain
    IPR011704 ATPase, dynein-related, AAA domain
    IPR026983 Dynein heavy chain
    IPR024317 Dynein heavy chain, AAA module D4
    IPR035706 Dynein heavy chain, ATP-binding dynein motor region
    IPR024743 Dynein heavy chain, coiled coil stalk
    IPR013594 Dynein heavy chain, domain-1
    IPR013602 Dynein heavy chain, domain-2
    IPR035699 Dynein heavy chain, hydrolytic ATP-binding dynein motor region
    IPR004273 Dynein heavy chain region D6 P-loop domain
    IPR027417 P-loop containing nucleoside triphosphate hydrolase
Molecular
Reagents
less
  • All nucleic 15
    cDNA 15

    Microarray probesets 2
Other
Accession IDs
less
MGD-MRK-36307, MGI:1920132, MGI:2441970
References
more
  • Summaries
    All 34
    Developmental Gene Expression 2
    Gene Ontology 6
    Phenotypes 9
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:215487 Thompson CL, et al., A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain. Neuron. 2014 Jul 16;83(2):309-23

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/11/2018
MGI 6.13
The Jackson Laboratory