Myo1f
Gene Detail

Symbol Name ID

Myo1f myosin IF MGI:107711

Synonyms

C330006B10Rik

Feature Type

protein coding gene

Genetic Map

Chromosome 17

17.98 cM, cytoband B-C
Detailed Genetic Map ± 1 cM


Mapping data(6)

Sequence Map

Chr17:33555719-33607764 bp, + strand From VEGA annotation of GRCm38   52046 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:56276  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Myo1f

Human homologs

Human Homolog		MYO1F, myosin IF
NCBI Gene ID		4542
neXtProt AC		NX_O00160
Human Chr (Location)		19p13.3-p13.2; chr19:8585674-8642331 (-)  GRCh37.p10

Alleles and phenotypes

All alleles(22) : Targeted(3) Gene trapped(19)
 

Mice homozygous for a knock-out allele exhibit impaired neutrophil migration and adhesion.

 

Gene Ontology (GO) classifications

All GO classifications: (17 annotations)

Process	defense response to Gram-positive bacterium, negative regulation of cell adhesion, ...
Component	cortical actin cytoskeleton, filamentous actin, ...
Function	actin binding, ATP binding, ...

External Resources: FuncBase

Expression

Literature Summary: (2 records)
Data Summary: Results (10)    Tissues (10)    Images (1)
Theiler Stages: 9, 16, 23, 28

Assay Type	Results
RNA in situ	1
RT-PCR	9

cDNA source data(12)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(14) cDNA(13) Primer pair(1)
Microarray probesets(5)

Other database links

VEGA Gene Model	OTTMUSG00000037201 (Evidence)
Ensembl Gene Model	ENSMUSG00000024300 (Evidence)
Entrez Gene	17916 (Evidence)
UniGene	42019
DFCI	TC1579321, TC1632102
DoTS	DT.101703804, DT.40151396, DT.99850421
NIA Mouse Gene Index	U017825
Consensus CDS Project	CCDS37567.1
International Mouse Knockout Project Status	Myo1f

Sequences

Length	Strain/Species
genomic	OTTMUSG00000037201	VEGA Gene Model | MGI Sequence Detail	52046	C57BL/6J
transcript	OTTMUST00000095910	VEGA | MGI Sequence Detail	3819	Not Applicable
polypeptide	OTTMUSP00000053543	VEGA | MGI Sequence Detail	1098	Not Applicable

All sequences(43) RefSeq(2) UniProt(8)

Polymorphisms

RFLP(1) : SNPs(215 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR000048	IQ motif, EF-hand binding site
InterPro	IPR001609	Myosin head, motor domain
InterPro	IPR010926	Myosin tail 2
InterPro	IPR027417	P-loop containing nucleoside triphosphate hydrolase
InterPro	IPR001452	Src homology-3 domain
Protein Ontology	PR:000010860	myosin-If

References

(Earliest) J:35477 Hasson T, et al., Mapping of unconventional myosins in mouse and human. Genomics. 1996 Sep 15;36(3):431-9
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(36)

Other accession IDs

MGD-MRK-36287, MGI:2148238