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Myo1f
Gene Detail
Symbol

Name
ID
Myo1f
myosin IF
MGI:107711
Synonyms
C330006B10Rik
Feature Type
protein coding gene
Genetic Map
Chromosome 17
17.98 cM, cytoband B-C
Detailed Genetic Map ± 1 cM


Mapping data(6)
Sequence Map
Chr17:33555719-33607764 bp, + strand
From VEGA annotation of GRCm38

  52046 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:56276  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: MYO1F
Gene Tree: Myo1f

Human
homologs
MYO1F, myosin IF
Orthology source: HomoloGene

IDs:
NCBI Gene ID: 4542
neXtProt AC: NX_O00160

Human Chr (Location): 19p13.3-p13.2; chr19:8520790-8577447 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(22) : Gene trapped(19) Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a knock-out allele exhibit impaired neutrophil migration and adhesion.
 
Interactions
Myo1f interacts with 214 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (18 annotations)
Process defense response to Gram-positive bacterium, negative regulation of cell adhesion, ...
Component cell, cortical actin cytoskeleton, ...
Function actin binding, ATP binding, ...
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (10)    Tissues (10)    Images (1)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 1
RT-PCR 9
cDNA source data(12)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase myo1f ; ZFIN myo1f    NEW 
Molecular
reagents
All nucleic(14) cDNA(13) Primer pair(1)
Microarray probesets(5)
Other database
links
VEGA Gene Model OTTMUSG00000037201 (Evidence)
Ensembl Gene Model ENSMUSG00000024300 (Evidence)
Entrez Gene 17916 (Evidence)
UniGene 42019
DFCI TC1632102, TC1579321
DoTS DT.101703804, DT.40151396, DT.99850421
NIA Mouse Gene Index U017825
Consensus CDS Project CCDS37567.1
International Mouse Phenotyping Consortium Status Myo1f
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000037201 VEGA Gene Model | MGI Sequence Detail 52046 C57BL/6J ±  kb
transcript OTTMUST00000095910 VEGA | MGI Sequence Detail 3819 Not Applicable 
polypeptide OTTMUSP00000053543 VEGA | MGI Sequence Detail 1098 Not Applicable 

For the selected sequences
All sequences(43) RefSeq(2) UniProt(8)
Polymorphisms
RFLP(1) : SNPs within 2kb(526 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR000048 IQ motif, EF-hand binding site
InterPro IPR001609 Myosin head, motor domain
InterPro IPR010926 Myosin tail 2
InterPro IPR027417 P-loop containing nucleoside triphosphate hydrolase
InterPro IPR001452 Src homology-3 domain
Protein Ontology PR:000010860 myosin-If
References
(Earliest) J:35477 Hasson T, et al., Mapping of unconventional myosins in mouse and human. Genomics. 1996 Sep 15;36(3):431-9
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(35)
Other
accession IDs
MGD-MRK-36287, MGI:2148238

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
06/30/2015
MGI 5.22
The Jackson Laboratory