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Myo7b Gene Detail
Summary
  • Symbol
    Myo7b
  • Name
    myosin VIIB
  • Feature Type
    protein coding gene
  • IDs
    MGI:107709
    NCBI Gene: 17922
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr18:31959234-32036931 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 18, 17.89 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    375 from dbSNP Build 142
  • Strain Annotations
    18
  • PCR
  • RFLP
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_107709
protein coding gene Chr18:31959234-32036961 (-)
129S1/SvImJ MGP_129S1SvImJ_G0024222
protein coding gene Chr18:30089883-30167821 (-)
A/J MGP_AJ_G0024188
protein coding gene Chr18:29086950-29165403 (-)
AKR/J MGP_AKRJ_G0024157
protein coding gene Chr18:29889425-29970065 (-)
BALB/cJ MGP_BALBcJ_G0024188
protein coding gene Chr18:29179884-29258146 (-)
C3H/HeJ MGP_C3HHeJ_G0023956
protein coding gene Chr18:29928229-30008547 (-)
C57BL/6NJ MGP_C57BL6NJ_G0024630
protein coding gene Chr18:31156120-31242757 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0022071
protein coding gene Chr18:29314757-29392590 (-)
CAST/EiJ MGP_CASTEiJ_G0023431
protein coding gene Chr18:29825612-29910678 (-)
CBA/J MGP_CBAJ_G0023924
protein coding gene Chr18:32118241-32195550 (-)
DBA/2J MGP_DBA2J_G0024056
protein coding gene Chr18:28760741-28838113 (-)
FVB/NJ MGP_FVBNJ_G0024022
protein coding gene Chr18:28464084-28542413 (-)
LP/J MGP_LPJ_G0024137
protein coding gene Chr18:30169800-30253065 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0024050
protein coding gene Chr18:33464905-33543061 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0024678
protein coding gene Chr18:29757924-29836187 (-)
PWK/PhJ MGP_PWKPhJ_G0023174
protein coding gene Chr18:28919369-28999021 (-)
SPRET/EiJ MGP_SPRETEiJ_G0022983
protein coding gene Chr18:29987202-30072352 (-)
WSB/EiJ MGP_WSBEiJ_G0023494
protein coding gene Chr18:29658307-29739224 (-)



Homology
more
  • Human Ortholog
    MYO7B, myosin VIIB
  • Vertebrate Orthologs
    9
  • Human Ortholog
    MYO7B, myosin VIIB
    Orthology source: HomoloGene, HGNC
  • Links
    NCBI Gene ID: 4648
    neXtProt AC: NX_Q6PIF6
    UniProt: Q6PIF6

  • Chr Location
    2q14.3; chr2:127535689-127637728 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    7 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 17922 NCBI Gene Model | MGI Sequence Detail 77698 C57BL/6J ±  kb
    transcript NM_032394 RefSeq | MGI Sequence Detail 6591 Not Specified  
    polypeptide Q99MZ6 UniProt | EBI | MGI Sequence Detail 2113 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 15
      cDNA 14
      Primer pair 1

      Microarray probesets 2
    Other
    Accession IDs
    less
    MGD-MRK-36285
    References
    more
    • Summaries
      All 30
      Developmental Gene Expression 1
      Gene Ontology 5
      Phenotypes 7
    • Earliest
      J:35477 Hasson T, et al., Mapping of unconventional myosins in mouse and human. Genomics. 1996 Sep 15;36(3):431-9
    • Latest
      J:246066 Sundberg JP, et al., Systematic screening for skin, hair, and nail abnormalities in a large-scale knockout mouse program. PLoS One. 2017;12(7):e0180682

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    last database update
    08/13/2019
    MGI 6.14
    The Jackson Laboratory