About   Help   FAQ
Itm2a
Gene Detail
 Symbol
Name
ID
Itm2a
integral membrane protein 2A
MGI:107706
Synonyms Bricd2a, Itm2
Feature Type protein coding gene
Genetic Map
Chromosome X
47.52 cM, cytoband A2-A3
Detailed Genetic Map ± 1 cM


Mapping data(5)
Sequence Map
ChrX:107397099-107403376 bp, - strand
From VEGA annotation of GRCm38

  6278 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:31269  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 chicken; 1 western clawed frog

Gene Tree: Itm2a

Human
homologs
Human Homolog ITM2A, integral membrane protein 2A
NCBI Gene ID 9452
neXtProt AC  NX_O43736
Human Synonyms  BRICD2A, E25A
Human Chr (Location)  Xq13.3-xq21.2; chrX:79360384-79367552 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(4) : Targeted(4)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a targeted allele are viable and fertile with no obvious phenotype.
 
Interactions
Itm2a interacts with 167 markers (Mir7-1, Mir10a, Mir10b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (2 annotations)
Component integral component of membrane, membrane
External Resources: FuncBase
Expression
Literature Summary: (8 records)
Data Summary: Results (44)    Tissues (15)    Images (1)
Theiler Stages: 15, 17, 19, 20, 21, 23, 24, 25, 26, 27
Assay TypeResults
RNA in situ 6
Northern blot 36
RT-PCR 2
cDNA source data(130)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(132) Genomic(1) cDNA(130) Primer pair(1)
Microarray probesets(2)
Other database
links
VEGA Gene ModelOTTMUSG00000018150 (Evidence)
Ensembl Gene ModelENSMUSG00000031239 (Evidence)
Entrez Gene16431 (Evidence)
UniGene193
DFCITC1572205
DoTSDT.535593
NIA Mouse Gene IndexU039633
Consensus CDS ProjectCCDS30349.1
International Mouse Knockout Project StatusItm2a
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000018150 VEGA Gene Model | MGI Sequence Detail 6278 C57BL/6J ±  kb
transcript OTTMUST00000043848 VEGA | MGI Sequence Detail 1744 Not Applicable 
polypeptide OTTMUSP00000019690 VEGA | MGI Sequence Detail 263 Not Applicable 

For the selected sequences
All sequences(23) RefSeq(2) UniProt(1)
Polymorphisms RFLP(1) : SNPs within 2kb(37 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR007084 BRICHOS domain
Protein Ontology PR:000032694 integral membrane protein 2A
References (Earliest) J:34815 Deleersnijder W, et al., Isolation of markers for chondro-osteogenic differentiation using cDNA library subtraction. Molecular cloning and characterization of a gene belonging to a novel multigene family of integral membrane proteins. J Biol Chem. 1996 Aug 9;271(32):19475-82
(Latest) J:200546 Lagha M, et al., Itm2a is a Pax3 target gene, expressed at sites of skeletal muscle formation in vivo. PLoS One. 2013;8(5):e63143
All references(34)
Other
accession IDs
MGD-MRK-36282, MGI:2147997

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
09/09/2014
MGI 5.19
The Jackson Laboratory