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Usp17le Gene Detail
Summary
  • Symbol
    Usp17le
  • Name
    ubiquitin specific peptidase 17-like E
  • Synonyms
    Dub3, Gm6596
  • Feature Type
    protein coding gene
  • IDs
    MGI:107697
    NCBI Gene: 625530
  • Alliance
Location &
Maps
more
  • Sequence Map
    Chr7:104768049-104777470 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 7, 55.69 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    39 from dbSNP Build 142
  • Strain Annotations
    16
  • RFLP
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_107697
protein coding gene Chr7:104767961-104777470 (-)
129S1/SvImJ MGP_129S1SvImJ_G0032657
protein coding gene Chr7:106554081-106555875 (+)
A/J MGP_AJ_G0032704
protein coding gene Chr7:105216382-105219864 (+)
AKR/J MGP_AKRJ_G0032637
protein coding gene Chr7:107783391-107787127 (-)
BALB/cJ MGP_BALBcJ_G0032712
protein coding gene Chr7:104796783-104799159 (-)
C3H/HeJ no annotation
C57BL/6NJ MGP_C57BL6NJ_G0033214
protein coding gene Chr7:112183685-112185212 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0030204
protein coding gene Chr7:107276477-107279578 (+)
CAST/EiJ MGP_CASTEiJ_G0031753
protein coding gene Chr7:99755336-99759212 (-)
CBA/J MGP_CBAJ_G0032396
protein coding gene Chr7:115927652-115930348 (-)
DBA/2J MGP_DBA2J_G0032547
protein coding gene Chr7:103512537-103515879 (+)
FVB/NJ MGP_FVBNJ_G0032499
protein coding gene Chr7:103139552-103241649 (-)
LP/J MGP_LPJ_G0032638
protein coding gene Chr7:109245026-109246392 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0032533
protein coding gene Chr7:117417114-117418687 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0033236
protein coding gene Chr7:106924912-106926491 (-)
PWK/PhJ MGP_PWKPhJ_G0031395
protein coding gene Chr7:95012094-95013860 (-)
SPRET/EiJ no annotation
WSB/EiJ MGP_WSBEiJ_G0031867
protein coding gene Chr7:107603308-107613254 (-)



Homology
less
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    9 phenotype references
  • All Mutations and Alleles
    2
  • Chemically induced (other)
    1
  • Radiation induced
    1
  • Genomic Mutations
    2 involving Usp17le
  • Incidental Mutations
    APF
  • Find Mice (IMSR)
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000043073 Ensembl Gene Model | MGI Sequence Detail 9422 C57BL/6J ±  kb
transcript ENSMUST00000053464 Ensembl | MGI Sequence Detail 1626 Not Applicable  
polypeptide ENSMUSP00000051716 Ensembl | MGI Sequence Detail 542 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    3 Sequences
  • EC
  • InterPro Domains
    IPR038765 Papain-like cysteine peptidase superfamily
    IPR001394 Peptidase C19, ubiquitin carboxyl-terminal hydrolase
    IPR018200 Ubiquitin specific protease, conserved site
    IPR028889 Ubiquitin specific protease domain
Molecular
Reagents
less
  • All nucleic 1
    Genomic 1
Other
Accession IDs
less
MGD-MRK-36273, MGI:3643640
References
more
  • Summaries
    All 29
    Gene Ontology 3
    Phenotypes 9
  • Earliest
    J:88307 Giometti CS, et al., The analysis of recessive lethal mutations in mice by using two-dimensional gel electrophoresis of liver proteins. Mutat Res. 1990 Sep;242(1):47-55
  • Latest
    J:206170 van der Laan S, et al., High Dub3 expression in mouse ESCs couples the G1/S checkpoint to pluripotency. Mol Cell. 2013 Nov 7;52(3):366-79

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
08/13/2019
MGI 6.14
The Jackson Laboratory