About   Help   FAQ
Cd1d1
Gene Detail
Symbol

Name
ID
Member of
Cd1d1
CD1d1 antigen
MGI:107674
Cd1 cluster
Synonyms
CD1.1, Cd1a, Cd1d, Ly-38
Feature Type
protein coding gene
Genetic Map
Chromosome 3
37.91 cM
Detailed Genetic Map ± 1 cM


Mapping data(15)
Sequence Map
Chr3:86995834-86999441 bp, - strand
From VEGA annotation of GRCm38

  3608 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:1337  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 4 cattle

Protein SuperFamily: T-cell surface glycoprotein CD1
Gene Tree: Cd1d1

Human
homologs
Human Homolog CD1D, CD1d molecule
NCBI Gene ID 912
neXtProt AC  NX_P15813
Human Synonyms  CD1A, R3
Human Chr (Location)  1q23.1; chr1:158179947-158186427 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(9) : Targeted(9)
Genomic Mutations involving Cd1d1 (2)
Incidental mutations (data from Mutagenetix , APF )
 
Homozygotes for targeted null mutations lack natural killer T cells, and mutant splenocytes fail to produce interleukin 4 (IL4).
 
Interactions
Cd1d1 interacts with 139 markers (Mir7-1, Mir19a, Mir19b-1, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (3 records)
Data Summary: Results (38)    Tissues (11)    Images (16)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 27
RT-PCR 11
cDNA source data(47)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(60) Genomic(5) cDNA(51) Primer pair(3) Other(1)
Microarray probesets(4)
Other database
links
VEGA Gene ModelOTTMUSG00000024396 (Evidence)
Ensembl Gene ModelENSMUSG00000028076 (Evidence)
Entrez Gene12479 (Evidence)
UniGene1894
DoTSDT.87069065
NIA Mouse Gene IndexU024225
PDB1Z5L, 1ZHN, 2AKR, 2FIK, 2GAZ, 2Q7Y, 3ARB, 3ARD, 3ARE, 3ARF, 3ARG, 3GML, 3GMM, 3GMN, 3GMO, 3GMP, 3GMQ, 3GMR, 3ILP, 3ILQ, 3O8X, 3O9W, 3QUX, 3QUY, 3QUZ, 3RTQ, 3RUG, 3RZC, 3SCM, 3SDA, 3SDC, 3SDD, 3T1F, 3TVM, 3UBX, 4APQ, 4ELM, 4IRJ, 4IRS, 4MNG, 1CD1, 3AU1, 3G08, 3HE6, 3HE7, 3MA7, 3QI9, 3TA3, 3TN0, 3TO4, 4EI5, 4MQ7
Consensus CDS ProjectCCDS17449.1
International Mouse Knockout Project StatusCd1d1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000024396 VEGA Gene Model | MGI Sequence Detail 3608 C57BL/6J ±  kb
transcript OTTMUST00000059801 VEGA | MGI Sequence Detail 1946 Not Applicable 
polypeptide OTTMUSP00000029117 VEGA | MGI Sequence Detail 336 Not Applicable 

For the selected sequences
All sequences(35) RefSeq(4) UniProt(4)
Polymorphisms
RFLP(6) : SNPs within 2kb(48 from dbSNP Build 137)    SNPs within 2kb including multiple locations(60)
Protein-related
information
ResourceIDDescription
InterPro IPR003597 Immunoglobulin C1-set
InterPro IPR007110 Immunoglobulin-like domain
InterPro IPR013783 Immunoglobulin-like fold
InterPro IPR011162 MHC classes I/II-like antigen recognition protein
InterPro IPR001039 MHC class I, alpha chain, alpha1/alpha2
InterPro IPR011161 MHC class I-like antigen recognition
Protein Ontology PR:000002028 antigen-presenting glycoprotein CD1d
References
(Earliest) J:17169 McMichael AJ, et al., A human thymocyte antigen defined by a hybrid myeloma monoclonal antibody. Eur J Immunol. 1979 Mar;9(3):205-10
(Latest) J:210013 Tyznik AJ, et al., Distinct requirements for activation of NKT and NK cells during viral infection. J Immunol. 2014 Apr 15;192(8):3676-85
All references(232)
Other
accession IDs
MGD-MRK-11979, MGD-MRK-1834, MGD-MRK-1836, MGD-MRK-36249, MGI:2139791

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
10/08/2014
MGI 5.20
The Jackson Laboratory