Gpm6b
Gene Detail

Symbol Name ID

Gpm6b glycoprotein m6b MGI:107672

Synonyms

Gpm6, M6B

Feature Type

protein coding gene

Genetic Map

Chromosome X

76.86 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)

Sequence Map

ChrX:166238911-166388988 bp, + strand From VEGA annotation of GRCm38   150078 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:128189  Vertebrate Homology Class
1 human; 1 mouse; 1 chimpanzee; 1 rhesus macaque; 1 dog; 1 chicken

Protein SuperFamily: myelin proteolipid protein
Gene Tree: Gpm6b

Human homologs

Human Homolog		GPM6B, glycoprotein M6B
NCBI Gene ID		2824
neXtProt AC		NX_Q13491
Human Synonyms		M6B
Human Chr (Location)		Xp22.2; chrX:13789062-13956831 (-)  GRCh37.p10

Alleles and phenotypes

All alleles(2) : Targeted(2)

Gene Ontology (GO) classifications

All GO classifications: (14 annotations)

Process	extracellular matrix assembly, negative regulation of protein localization to cell surface, ...
Component	integral to membrane, membrane, ...

External Resources: FuncBase

Expression

Literature Summary: (10 records)
Data Summary: Results (232)    Tissues (102)    Images (45)
Theiler Stages: 17, 19, 20, 21, 22, 23, 24, 26, 28

Assay Type	Results
Immunohistochemistry	40
RNA in situ	189
RT-PCR	3

cDNA source data(130)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(133) cDNA(132) Primer pair(1)
Microarray probesets(6)

Other database links

VEGA Gene Model	OTTMUSG00000019536 (Evidence)
Ensembl Gene Model	ENSMUSG00000031342 (Evidence)
Entrez Gene	14758 (Evidence)
UniGene	222320
DFCI	TC1580519, TC1589862, TC1591117, TC1601676, TC1603004, TC1604881, TC1610729, TC1645370
DoTS	DT.101218932, DT.101403589, DT.101403591, DT.101403593, DT.111031180, DT.40136064, DT.50316703, DT.91601618, DT.91601619, DT.94288101, DT.94288112, DT.97402978, DT.99863943, DT.99863944
NIA Mouse Gene Index	U043807
Consensus CDS Project	CCDS30526.1, CCDS53243.1, CCDS53244.1, CCDS53245.1, CCDS53246.1, CCDS53247.1
International Mouse Knockout Project Status	Gpm6b

Sequences

Length	Strain/Species
genomic	OTTMUSG00000019536	VEGA Gene Model | MGI Sequence Detail	150078	C57BL/6J
transcript	OTTMUST00000046660	VEGA | MGI Sequence Detail	3203	Not Applicable
polypeptide	OTTMUSP00000021078	VEGA | MGI Sequence Detail	328	Not Applicable

All sequences(123) RefSeq(18) UniProt(6)

Polymorphisms

SNPs(634 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR001614	Myelin proteolipid protein PLP
InterPro	IPR018237	Myelin proteolipid protein PLP, conserved site
Protein Ontology	PR:000008179	neuronal membrane glycoprotein M6-b

References

(Earliest) J:26641 Baumrind NL, et al., EMA: a developmentally regulated cell-surface glycoprotein of CNS neurons that is concentrated at the leading edge of growth cones. Dev Dyn. 1992 Aug;194(4):311-25
(Latest) J:193822 Lumayag S, et al., Inactivation of the microRNA-183/96/182 cluster results in syndromic retinal degeneration. Proc Natl Acad Sci U S A. 2013 Feb 5;110(6):E507-16
All references(46)

Other accession IDs

MGD-MRK-33055, MGD-MRK-36247, MGI:2147902