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Usp39 Gene Detail
Summary
  • Symbol
    Usp39
  • Name
    ubiquitin specific peptidase 39
  • Synonyms
    CGI-21, D6Wsu157e, SAD1
  • Feature Type
    protein coding gene
  • IDs
    MGI:107622
    NCBI Gene: 28035
  • Gene Overview
    MyGene.info: USP39
Location & Maps
more
  • Sequence Map
    Chr6:72318678-72345184 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      26507 bp   ±  kb flank

  • Genome Browsers
Homology
more
  • Human Ortholog
    USP39, ubiquitin specific peptidase 39
  • Vertebrate Orthologs
    10
  • Human Ortholog
    USP39, ubiquitin specific peptidase 39
    Orthology source: HomoloGene
  • Synonyms
    65K, CGI-21, HSPC332, SAD1, SNRNP65
  • Links
    NCBI Gene ID: 10713
    neXtProt AC: NX_Q53GS9

  • Chr Location
    2p11.2; chr2:85602842-85649284 (+)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 13183
    1 human;1 mouse;1 rat;1 chimpanzee;1 rhesus macaque;1 cattle;1 dog;1 chicken;1 western clawed frog;1 zebrafish
  • HCOP
    human homology predictions: USP39
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    9 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryogenesis
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
tumorigenesis
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    8
  • Gene trapped
    3
  • Spontaneous
    1
  • Targeted
    4
  • Genomic Mutations
    1 involving Usp39
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000023516 VEGA Gene Model | MGI Sequence Detail 26507 C57BL/6J ±  kb
transcript OTTMUST00000057291 VEGA | MGI Sequence Detail 2244 Not Applicable  
polypeptide OTTMUSP00000027624 VEGA | MGI Sequence Detail 564 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    172 from dbSNP Build 142
Protein
Information
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  • UniProt
    2 Sequences
  • Protein Ontology
    PR:000017178 U4/U6.U5 tri-snRNP-associated protein 2
  • InterPro Domains
    IPR001394 Peptidase C19, ubiquitin carboxyl-terminal hydrolase
    IPR028889 Ubiquitin specific protease domain
    IPR015880 Zinc finger, C2H2-like
    IPR013083 Zinc finger, RING/FYVE/PHD-type
    IPR001607 Zinc finger, UBP-type
Molecular
Reagents
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  • All nucleic 94
    cDNA 92
    Primer pair 2

    Microarray probesets 4
Other
Accession IDs
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MGD-MRK-36196, MGI:2141363, MGI:2141516
References
more
  • Summaries
    All 38
    Developmental Gene Expression 6
    Gene Ontology 2
    Phenotypes 9
  • Earliest
    J:44486 Lesh JS, et al., Mapping of the mouse corticotropin-releasing hormone receptor 2 gene (Crhr2) to chromosome 6. Mamm Genome. 1997 Dec;8(12):944-5
  • Latest
    J:149737 Sansom SN, et al., The level of the transcription factor Pax6 is essential for controlling the balance between neural stem cell self-renewal and neurogenesis. PLoS Genet. 2009 Jun;5(6):e1000511

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
05/17/2016
MGI 6.03
The Jackson Laboratory