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Npat Gene Detail
Summary
  • Symbol
    Npat
  • Name
    nuclear protein in the AT region
  • Feature Type
    protein coding gene
  • IDs
    MGI:107605
    NCBI Gene: 244879
  • Gene Overview
    MyGene.info: NPAT
Location & Maps
more
  • Sequence Map
    Chr9:53537047-53574342 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      37296 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 9, 29.12 cM
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    NPAT, nuclear protein, coactivator of histone transcription
  • Vertebrate Orthologs
    9
  • Human Ortholog
    NPAT, nuclear protein, coactivator of histone transcription
    Orthology source: HGNC, HomoloGene
  • Synonyms
    E14, E14/NPAT, p220
  • Links
    NCBI Gene ID: 4863
    neXtProt AC: NX_Q14207

  • Chr Location
    11q22-q23; chr11:108157215-108222638 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    11 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000031590 VEGA Gene Model | MGI Sequence Detail 37296 C57BL/6J ±  kb
transcript OTTMUST00000078238 VEGA | MGI Sequence Detail 6062 Not Applicable  
polypeptide OTTMUSP00000041587 VEGA | MGI Sequence Detail 1420 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    46 from dbSNP Build 142
  • RFLP
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 10
    cDNA 10

    Microarray probesets 4
Other
Accession IDs
less
MGD-MRK-36179, MGI:2143040, MGI:2143360
References
more
  • Summaries
    All 34
    Developmental Gene Expression 1
    Gene Ontology 2
    Phenotypes 11
  • Earliest
    J:33856 Matsuda Y, et al., Comparative genome mapping of the ataxia-telangiectasia region in mouse, rat, and Syrian hamster. Genomics. 1996 Jun 15;34(3):347-52
  • Latest
    J:181069 De Cola A, et al., FLASH is essential during early embryogenesis and cooperates with p73 to regulate histone gene transcription. Oncogene. 2012 Feb 2;31(5):573-82

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
08/17/2016
MGI 6.05
The Jackson Laboratory