About   Help   FAQ
Tbca Gene Detail
Summary
  • Symbol
    Tbca
  • Name
    tubulin cofactor A
  • Synonyms
    co-chaperonin associated with a- & b-tubulin, cofactor A, Tbca13
  • Feature Type
    protein coding gene
  • IDs
    MGI:107549
    NCBI Gene: 21371
  • Gene Overview
    MyGene.info: TBCA
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr13:94788943-94842899 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 13, 49.22 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    274 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_107549
protein coding gene Chr13:94788910-94842922 (.)
129S1/SvImJ MGP_129S1SvImJ_G0020834
protein coding gene Chr13:96216266-96281560 (+)
A/J MGP_AJ_G0020788
protein coding gene Chr13:92614411-92668789 (+)
AKR/J MGP_AKRJ_G0020762
protein coding gene Chr13:95444973-95502335 (+)
BALB/cJ MGP_BALBcJ_G0020785
protein coding gene Chr13:93294927-93349245 (+)
C3H/HeJ MGP_C3HHeJ_G0020578
protein coding gene Chr13:95153042-95206916 (+)
C57BL/6NJ MGP_C57BL6NJ_G0021221
protein coding gene Chr13:99140759-99199088 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0018790
protein coding gene Chr13:88449565-88503493 (+)
CAST/EiJ MGP_CASTEiJ_G0020097
protein coding gene Chr13:94417284-94472140 (+)
CBA/J MGP_CBAJ_G0020537
protein coding gene Chr13:103082679-103142931 (+)
DBA/2J MGP_DBA2J_G0020662
protein coding gene Chr13:92405821-92460030 (+)
FVB/NJ MGP_FVBNJ_G0020643
protein coding gene Chr13:91187008-91242097 (+)
LP/J MGP_LPJ_G0020737
protein coding gene Chr13:96322584-96382151 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0020671
protein coding gene Chr13:103533760-103593488 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0021261
protein coding gene Chr13:94845152-94900546 (+)
PWK/PhJ MGP_PWKPhJ_G0019849
protein coding gene Chr13:91125878-91181726 (+)
SPRET/EiJ MGP_SPRETEiJ_G0019673
protein coding gene Chr13:91097288-91155067 (+)
WSB/EiJ MGP_WSBEiJ_G0020154
protein coding gene Chr13:95328722-95385188 (+)



Homology
more
  • Human Ortholog
    TBCA, tubulin folding cofactor A
  • Vertebrate Orthologs
    9
  • Human Ortholog
    TBCA, tubulin folding cofactor A
    Orthology source: HomoloGene, HGNC
  • Links
    NCBI Gene ID: 6902
    neXtProt AC: NX_O75347
    UniProt: O75347

  • Chr Location
    5q14.1; chr5:77691169-77776361 (-)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 3388
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed
  • HCOP
    human homology predictions: TBCA
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    9 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 21371 NCBI Gene Model | MGI Sequence Detail 53957 C57BL/6J ±  kb
transcript NM_009321 RefSeq | MGI Sequence Detail 503 C57BL/6  
polypeptide P48428 UniProt | EBI | MGI Sequence Detail 108 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    4 Sequences
  • InterPro Domains
    IPR004226 Tubulin binding cofactor A
    IPR036126 Tubulin binding cofactor A superfamily
Molecular
Reagents
less
  • All nucleic 37
    cDNA 37

    Microarray probesets 5
Other
Accession IDs
less
MGD-MRK-36120
References
more
  • Summaries
    All 37
    Developmental Gene Expression 1
    Gene Ontology 3
    Phenotypes 9
  • Earliest
    J:182573 Roderick TH, Producing and detecting paracentric chromosomal inversions in mice. Mutat Res. 1971 Jan;11(1):59-69
  • Latest
    J:189827 Nolasco S, et al., The expression of tubulin cofactor A (TBCA) is regulated by a noncoding antisense Tbca RNA during testis maturation. PLoS One. 2012;7(8):e42536

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
11/13/2018
MGI 6.13
The Jackson Laboratory