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Lgals4
Gene Detail
Symbol

Name
ID
Lgals4
lectin, galactose binding, soluble 4
MGI:107536
Synonyms
galectin-4
Feature Type
protein coding gene
Genetic Map
Chromosome 7
16.94 cM
Detailed Genetic Map ± 1 cM


Mapping data(5)
Sequence Map
Chr7:28833854-28841708 bp, + strand
From VEGA annotation of GRCm38

  7855 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:21239  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 western clawed frog

HCOP human homology predictions: LGALS4
Protein SuperFamily: galectin
Gene Tree: Lgals4

Human
homologs
LGALS4, lectin, galactoside-binding, soluble, 4
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 3960
neXtProt AC: NX_P56470

Human Synonyms: GAL4, L36LBP

Human Chr (Location): 19q13.2; chr19:38801671-38813544 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(1) : Gene trapped(1)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Lgals4 interacts with 16 markers (Mir9-1, Mir9-2, Mir9-3, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (5 annotations)
Component extracellular space
Function carbohydrate binding, galactoside binding, ...
External Resources: FuncBase
Expression
Literature Summary: (3 records)
Data Summary: Results (36)    Tissues (16)    Images (15)    Tissue x Stage Matrix (view)
Assay TypeResults
Immunohistochemistry 1
RNA in situ 22
RT-PCR 13
cDNA source data(13)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase LOC100496749    NEW 
Molecular
reagents
All nucleic(18) Genomic(1) cDNA(15) Primer pair(2)
Microarray probesets(2)
Other database
links
VEGA Gene Model OTTMUSG00000022686 (Evidence)
Ensembl Gene Model ENSMUSG00000053964 (Evidence)
Entrez Gene 16855 (Evidence)
DFCI TC1575048
DoTS DT.102534270, DT.94339745
PDB 2DYC, 3I8T
Consensus CDS Project CCDS21058.1
International Mouse Phenotyping Consortium Status Lgals4
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000022686 VEGA Gene Model | MGI Sequence Detail 7855 C57BL/6J ±  kb
transcript OTTMUST00000054398 VEGA | MGI Sequence Detail 1384 Not Applicable 
polypeptide OTTMUSP00000025965 VEGA | MGI Sequence Detail 326 Not Applicable 

For the selected sequences
All sequences(45) RefSeq(4) UniProt(6)
Polymorphisms
RFLP(1) : SNPs within 2kb(103 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR013320 Concanavalin A-like lectin/glucanase, subgroup
InterPro IPR015533 Galectin-4/6
InterPro IPR001079 Galectin, carbohydrate recognition domain
Protein Ontology PR:000009773 galectin-4
References
(Earliest) J:33381 Jonassen T, et al., Isolation and sequencing of the rat Coq7 gene and the mapping of mouse Coq7 to chromosome 7. (Correction appears in Arch Biochem Biophys 1996; 335(1):227). Arch Biochem Biophys. 1996 Jun 15;330(2):285-9
(Latest) J:204419 Takeuchi T, et al., Mammalian galectins bind galactosebeta1-4fucose disaccharide, a unique structural component of protostomial N-type glycoproteins. Biochem Biophys Res Commun. 2013 Jul 5;436(3):509-13
All references(31)
Other
accession IDs
MGD-MRK-36106

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/18/2015
MGI 6.0
The Jackson Laboratory