About   Help   FAQ
Art1 Gene Detail
Summary
  • Symbol
    Art1
  • Name
    ADP-ribosyltransferase 1
  • Synonyms
    ADPRT, Yac-1
  • Feature Type
    protein coding gene
  • IDs
    MGI:107511
    NCBI Gene: 11870
Location & Maps
more
  • Sequence Map
    Chr7:102101743-102111148 bp, + strand
  • From Ensembl annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      9406 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 7, 54.71 cM
  • Mapping Data
    3 experiments
Homology
more
  • Human Ortholog
    ART1, ADP-ribosyltransferase 1
  • Vertebrate Orthologs
    14
  • Human Ortholog
    ART1, ADP-ribosyltransferase 1
    Orthology source: HGNC, HomoloGene
  • Synonyms
    ART2, ARTC1, CD296, RT6
  • Links
    NCBI Gene ID: 417
    neXtProt AC: NX_P52961

  • Chr Location
    11p15; chr11:3642234-3665075 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    17 phenotype references
  • All Mutations and Alleles
    10
  • Chemically induced (other)
    1
  • Gene trapped
    5
  • Radiation induced
    1
  • Targeted
    3
  • Genomic Mutations
    2 involving Art1
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000030996 Ensembl Gene Model | MGI Sequence Detail 9406 C57BL/6J ±  kb
transcript ENSMUST00000033300 Ensembl | MGI Sequence Detail 1417 Not Applicable  
polypeptide ENSMUSP00000033300 Ensembl | MGI Sequence Detail 325 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    226 from dbSNP Build 142
  • RFLP
Protein
Information
less
  • UniProt
    2 Sequences
  • Protein Ontology
    PR:000001815 GPI-linked NAD(P)(+)--arginine ADP-ribosyltransferase 1
  • EC
  • InterPro Domains
    IPR000768 NAD:arginine ADP-ribosyltransferase, ART
Molecular
Reagents
less
  • All nucleic 33
    Genomic 4
    cDNA 26
    Primer pair 2
    Other 1

    Microarray probesets 6
Other
Accession IDs
less
MGD-MRK-36081
References
more
  • Summaries
    All 38
    Developmental Gene Expression 5
    Gene Ontology 8
    Phenotypes 17
  • Earliest
    J:34530 Okazaki IJ, et al., Molecular characterization of a glycosylphosphatidylinositol-linked ADP-ribosyltransferase from lymphocytes. Blood. 1996 Aug 1;88(3):915-21
  • Latest
    J:188535 Wang J, et al., NAD induces astrocyte calcium flux and cell death by ART2 and P2X7 pathway. Am J Pathol. 2012 Sep;181(3):746-52

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
07/19/2016
MGI 6.04
The Jackson Laboratory