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Wfdc18 Gene Detail
Summary
  • Symbol
    Wfdc18
  • Name
    WAP four-disulfide core domain 18
  • Synonyms
    Expi, Kal1, WDNM1
  • Feature Type
    protein coding gene
  • IDs
    MGI:107506
    NCBI Gene: 14038
Location & Maps
more
  • Sequence Map
    Chr11:83709015-83711348 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      2334 bp   ±  kb flank

  • Genome Browsers
Homology
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Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    12 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryogenesis
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
tumorigenesis
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    5
  • Chemically induced (other)
    1
  • Targeted
    4
  • Genomic Mutations
    2 involving Wfdc18
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000000970 VEGA Gene Model | MGI Sequence Detail 2334 C57BL/6J ±  kb
transcript OTTMUST00000001906 VEGA | MGI Sequence Detail 521 Not Applicable  
polypeptide OTTMUSP00000000922 VEGA | MGI Sequence Detail 74 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    34 from dbSNP Build 137
Protein
Information
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  • UniProt
    3 Sequences
  • Protein Ontology
    PR:000007293 extracellular peptidase inhibitor
  • InterPro Domains
    IPR029716 WAP four-disulfide core domain protein 18
    IPR008197 WAP-type 'four-disulfide core' domain
Molecular
Reagents
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  • All nucleic 87
    Genomic 1
    cDNA 86

    Microarray probesets 3
Other
Accession IDs
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MGD-MRK-36076
References
more
  • Summaries
    All 27
    Developmental Gene Expression 2
    Gene Ontology 2
    Phenotypes 12
  • Earliest
    J:21836 Morrison BW, et al., neu and ras initiate murine mammary tumors that share genetic markers generally absent in c-myc and int-2-initiated tumors. Oncogene. 1994 Dec;9(12):3417-26
  • Latest
    J:223102 Karp NA, et al., Impact of temporal variation on design and analysis of mouse knockout phenotyping studies. PLoS One. 2014;9(10):e111239

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
02/02/2016
MGI 6.02
The Jackson Laboratory