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Wfdc18
Gene Detail
Symbol

Name
ID
Wfdc18
WAP four-disulfide core domain 18
MGI:107506
Synonyms
Expi, Kal1, WDNM1
Feature Type
protein coding gene
Genetic Map
Chromosome 11
51.23 cM, cytoband B5
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr11:83709015-83711348 bp, + strand
From VEGA annotation of GRCm38

  2334 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
Gene Tree: Wfdc18
Mutations,
alleles, and
phenotypes
All mutations/alleles(4) : Targeted(4)
Genomic Mutations involving Wfdc18 (1)
Interactions
Wfdc18 interacts with 18 markers (Mir140, Mir141, Mir144, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (5 annotations)
Process negative regulation of peptidase activity
Component extracellular region
Function peptidase inhibitor activity
External Resources: FuncBase
Expression
Literature Summary: (2 records)
cDNA source data(86)
Other mouse links: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(87) Genomic(1) cDNA(86)
Microarray probesets(3)
Other database
links
VEGA Gene Model OTTMUSG00000000970 (Evidence)
Ensembl Gene Model ENSMUSG00000000983 (Evidence)
Entrez Gene 14038 (Evidence)
UniGene 1650
DFCI TC1577563
DoTS DT.99865170, DT.97371082
NIA Mouse Gene Index U013093
Consensus CDS Project CCDS25175.1
International Mouse Phenotyping Consortium Status Wfdc18
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000000970 VEGA Gene Model | MGI Sequence Detail 2334 C57BL/6J ±  kb
transcript OTTMUST00000001906 VEGA | MGI Sequence Detail 521 Not Applicable 
polypeptide OTTMUSP00000000922 VEGA | MGI Sequence Detail 74 Not Applicable 

For the selected sequences
All sequences(31) RefSeq(2) UniProt(3)
Polymorphisms
SNPs within 2kb(34 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR008197 Whey acidic protein-type 4-disulphide core
Protein Ontology PR:000007293 extracellular peptidase inhibitor
References
(Earliest) J:21836 Morrison BW, et al., neu and ras initiate murine mammary tumors that share genetic markers generally absent in c-myc and int-2-initiated tumors. Oncogene. 1994 Dec;9(12):3417-26
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(30)
Other
accession IDs
MGD-MRK-36076

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
05/20/2015
MGI 5.22
The Jackson Laboratory