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Pxmp2
Gene Detail
 Symbol
Name
ID
Pxmp2
peroxisomal membrane protein 2
MGI:107487
Synonyms 22kDa, PMP22
Feature Type protein coding gene
Genetic Map
Chromosome 5
53.44 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr5:110274282-110286186 bp, - strand
From VEGA annotation of GRCm38

  11905 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:32062  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 rhesus macaque; 1 cattle; 1 dog; 1 western clawed frog; 1 zebrafish

Protein SuperFamily: mitocondrial membrane protein, Mpv17/PMP22
Gene Tree: Pxmp2

Human
homologs
Human Homolog PXMP2, peroxisomal membrane protein 2, 22kDa
NCBI Gene ID 5827
neXtProt AC  NX_Q9NR77
Human Synonyms  PMP22
Human Chr (Location)  12q24.33; chr12:132687606-132704991 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(6) : Gene trapped(3) Targeted(3)
 
Mice homozygous for a null mutation display impaired lactation, increased serum urate levels, elevated urinary clearence of urate, and abnormal liver peroxisomal membrane permeability.
 
Interactions
Pxmp2 interacts with 66 markers (Mir20a, Mir22, Mir23a, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (9 annotations)
Component cytoplasm, integral component of membrane, ...
External Resources: FuncBase
Expression
cDNA source data(32)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(33) cDNA(32) Primer pair(1)
Microarray probesets(4)
Other database
links
VEGA Gene ModelOTTMUSG00000026216 (Evidence)
Ensembl Gene ModelENSMUSG00000029499 (Evidence)
Entrez Gene19301 (Evidence)
UniGene21853
DFCITC1580973, TC1669533
DoTSDT.532949
NIA Mouse Gene IndexU026555
Consensus CDS ProjectCCDS19524.1
International Mouse Knockout Project StatusPxmp2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000026216 VEGA Gene Model | MGI Sequence Detail 11905 C57BL/6J ±  kb
transcript OTTMUST00000064832 VEGA | MGI Sequence Detail 1041 Not Applicable 
polypeptide OTTMUSP00000032236 VEGA | MGI Sequence Detail 193 Not Applicable 

For the selected sequences
All sequences(32) RefSeq(2) UniProt(3)
Polymorphisms SNPs within 2kb(128 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR007248 Mpv17/PMP22
Protein Ontology PR:000013509 peroxisomal membrane protein 2
References (Earliest) J:27776 Bryant DD, et al., Differential evolution and expression of murine peroxisomal membrane protein genes. Biochem Mol Med. 1995 Jun;55(1):22-30
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(35)
Other
accession IDs
MGD-MRK-36055

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory