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Rgl1 Gene Detail
Summary
  • Symbol
    Rgl1
  • Name
    ral guanine nucleotide dissociation stimulator,-like 1
  • Synonyms
    Rgl
  • Feature Type
    protein coding gene
  • IDs
    MGI:107484
    NCBI Gene: 19731
Location & Maps
more
  • Sequence Map
    Chr1:152516760-152766351 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      249592 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 1, 64.85 cM, cytoband G2
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    RGL1, ral guanine nucleotide dissociation stimulator like 1
  • Vertebrate Orthologs
    9
  • Human Ortholog
    RGL1, ral guanine nucleotide dissociation stimulator like 1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    RGL
  • Links
    NCBI Gene ID: 23179
    neXtProt AC: NX_Q9NZL6

  • Chr Location
    1q25.3; chr1:183636047-183928551 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    4 phenotype references
  • All Mutations and Alleles
    7
  • Chemically induced (other)
    2
  • Gene trapped
    1
  • Targeted
    4
  • Genomic Mutations
    2 involving Rgl1
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000022514 VEGA Gene Model | MGI Sequence Detail 249592 C57BL/6J ±  kb
transcript OTTMUST00000053906 VEGA | MGI Sequence Detail 5092 Not Applicable  
polypeptide OTTMUSP00000025663 VEGA | MGI Sequence Detail 803 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    2614 from dbSNP Build 142
Protein
Information
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  • UniProt
    5 Sequences
  • Protein Ontology
    PR:000013936 ral guanine nucleotide dissociation stimulator-like 1
  • PDB
  • InterPro Domains
    IPR030748 Ral guanine nucleotide dissociation stimulator-like 1
    IPR000159 Ras-associating (RA) domain
    IPR019804 Ras guanine-nucleotide exchange factor, conserved site
    IPR023578 Ras guanine nucleotide exchange factor domain
    IPR001895 Ras guanine-nucleotide exchange factors catalytic domain
    IPR000651 Ras-like guanine nucleotide exchange factor, N-terminal
    IPR029071 Ubiquitin-related domain
Molecular
Reagents
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  • All nucleic 57
    cDNA 57

    Microarray probesets 6
Other
Accession IDs
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MGD-MRK-36052
References
more
  • Summaries
    All 24
    Developmental Gene Expression 1
    Gene Ontology 2
    Phenotypes 4
  • Earliest
    J:47441 Kikuchi A, et al., ralGDS family members interact with the effector loop of ras p21. Mol Cell Biol. 1994 Nov;14(11):7483-91
  • Latest
    J:162220 Magdaleno S, et al., BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. PLoS Biol. 2006 Apr;4(4):e86

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/29/2016
MGI 6.06
The Jackson Laboratory