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Csn3
Gene Detail
 Symbol
Name
ID
Member of
Csn3
casein kappa
MGI:107461
Csn cluster
Synonyms CSN10, Csnk
Feature Type protein coding gene
Genetic Map
Chromosome 5
43.56 cM
Detailed Genetic Map ± 1 cM


Mapping data(9)
Sequence Map
Chr5:87925579-87932665 bp, + strand
From VEGA annotation of GRCm38

  7087 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:3818  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 dog

Protein SuperFamily: kappa-casein
Gene Tree: Csn3

Human
homologs
Human Homolog CSN3, casein kappa
NCBI Gene ID 1448
neXtProt AC  NX_P07498
Human Synonyms  CSN10, CSNK, KCA
Human Chr (Location)  4q21.1; chr4:70242616-70251428 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(5) : Gene trapped(3) Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a null mutation display lactation failure and abnormal milk composition, but are fertile.
 
Interactions
Csn3 interacts with 148 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (7 annotations)
Process lactation, protein stabilization
Component extracellular region, extracellular space
Function molecular_function
External Resources: FuncBase
Expression
Literature Summary: (1 records)
Data Summary: Results (41)    Tissues (27)    Images (13)
Theiler Stages: 19, 23, 28
Assay TypeResults
RNA in situ 41
cDNA source data(760)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(769) Genomic(6) cDNA(762) Other(1)
Microarray probesets(4)
Other database
links
VEGA Gene ModelOTTMUSG00000025838 (Evidence)
Ensembl Gene ModelENSMUSG00000001622 (Evidence)
Entrez Gene12994 (Evidence)
UniGene296303
DFCITC1573796, TC1589380, TC1589747, TC1627176
DoTSDT.101136409, DT.87059791, DT.87060207, DT.91335025, DT.91562600, DT.94150878, DT.97416474
NIA Mouse Gene IndexU005747
Consensus CDS ProjectCCDS19396.1
International Mouse Knockout Project StatusCsn3
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000025838 VEGA Gene Model | MGI Sequence Detail 7087 C57BL/6J ±  kb
transcript OTTMUST00000063656 VEGA | MGI Sequence Detail 991 Not Applicable 
polypeptide OTTMUSP00000031503 VEGA | MGI Sequence Detail 181 Not Applicable 

For the selected sequences
All sequences(50) RefSeq(4) UniProt(2)
Polymorphisms SNPs within 2kb(47 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR000117 Kappa casein
Protein Ontology PR:000005942 kappa-casein
References (Earliest) J:35109 Thompson MD, et al., Molecular cloning of mouse mammary gland kappa-casein: comparison with rat kappa-casein and rat and human gamma-fibrinogen. DNA. 1985 Aug;4(4):263-71
(Latest) J:200642 Komori R, et al., Csn3 gene is regulated by all-trans retinoic acid during neural differentiation in mouse P19 cells. PLoS One. 2013;8(4):e61938
All references(44)
Other
accession IDs
MGD-MRK-35932, MGI:2141168

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/16/2014
MGI 5.19
The Jackson Laboratory