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Cox6b1
Gene Detail
Symbol

Name
ID
Cox6b1
cytochrome c oxidase, subunit VIb polypeptide 1
MGI:107460
Synonyms
2010000G05Rik
Feature Type
protein coding gene
Genetic Map
Chromosome 7
18.84 cM, cytoband A3
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr7:30616974-30626151 bp, - strand
From NCBI annotation of GRCm38

  9178 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:39658  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: COX6B1
Protein SuperFamily: cytochrome-c oxidase, subunit VIb
Gene Tree: Cox6b1

Human
homologs
COX6B1, cytochrome c oxidase subunit Vib polypeptide 1 (ubiquitous)
Orthology source: HomoloGene, HGNC

IDs:
NCBI Gene ID: 1340
neXtProt AC: NX_P14854

Human Synonyms: COX6B, COXG, COXVIb1

Human Chr (Location): 19q13.1; chr19:35648223-35658784 (+)  GRCh38.p2

Disease Associations: (1) Diseases Associated with Human COX6B1

Mutations,
alleles, and
phenotypes
All mutations/alleles(43) : Gene trapped(41) Targeted(2)
Incidental mutations (data from APF )
Interactions
Cox6b1 interacts with 23 markers (Mir19a, Mir19b-1, Mir19b-2, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (4 annotations)
Component mitochondrial inner membrane, mitochondrion
Function cytochrome-c oxidase activity
External Resources: FuncBase
Expression
Literature Summary: (3 records)
Data Summary: Results (110)    Tissues (104)    Images (13)    Tissue x Stage Matrix (view)
Assay TypeResults
Immunohistochemistry 4
RNA in situ 94
RT-PCR 12
cDNA source data(329)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase cox6b1 ; ZFIN cox6b1    NEW 
Molecular
reagents
All nucleic(332) cDNA(331) Primer pair(1)
Microarray probesets(3)
Other database
links
Ensembl Gene Model ENSMUSG00000036751 (Evidence)
Entrez Gene 110323 (Evidence)
UniGene 400
DFCI TC1573960
DoTS DT.97336421, DT.55200929
NIA Mouse Gene Index U028394
Consensus CDS Project CCDS39887.1
International Mouse Phenotyping Consortium Status Cox6b1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 110323 NCBI Gene Model | MGI Sequence Detail 9178 C57BL/6J ±  kb
transcript NM_025628 RefSeq | MGI Sequence Detail 505 C57BL/6 
polypeptide P56391 UniProt | EBI | MGI Sequence Detail 86 Not Applicable 

For the selected sequences
All sequences(17) RefSeq(2) UniProt(1)
Polymorphisms
RFLP(1) : SNPs within 2kb(131 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR003213 Cytochrome c oxidase, subunit VIb
Protein Ontology PR:000005783 cytochrome c oxidase subunit 6B1
Graphical View of Protein Domain Structure
References
(Earliest) J:34617 Stubbs L, et al., Detailed comparative map of human chromosome 19q and related regions of the mouse genome. Genomics. 1996 Aug 1;35(3):499-508
(Latest) J:210222 Hupe M, et al., Evaluation of TRAP-sequencing technology with a versatile conditional mouse model. Nucleic Acids Res. 2014 Jan;42(2):e14
All references(36)
Other
accession IDs
MGD-MRK-35931, MGI:1913792

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
05/20/2015
MGI 5.22
The Jackson Laboratory