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Dbx2
Gene Detail
Symbol

Name
ID
Dbx2
developing brain homeobox 2
MGI:107445
Synonyms
9430056A22Rik, LOC383001
Feature Type
protein coding gene
Genetic Map
Chromosome 15
50.47 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr15:95623563-95655960 bp, - strand
From VEGA annotation of GRCm38

  32398 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:54981  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 chicken; 1 western clawed frog

HCOP human homology predictions: DBX2
Gene Tree: Dbx2

Human
homologs
DBX2, developing brain homeobox 2
Orthology source: HomoloGene, HGNC

IDs:
NCBI Gene ID: 440097
neXtProt AC: NX_Q6ZNG2

Human Chr (Location): 12q12; chr12:45014756-45051099 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(2) : Radiation induced(1) Targeted(1)
Genomic Mutations involving Dbx2 (1)
Incidental mutations (data from Mutagenetix , APF )
Phenotype Images(2)
Interactions
Dbx2 interacts with 208 markers (Mir1b, Mir19a, Mir19b-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (2 annotations)
Process biological_process
Component cellular_component
External Resources: FuncBase
Expression
Literature Summary: (29 records)
Data Summary: Results (190)    Tissues (155)    Images (41)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 190
cDNA source data(6)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: GEISHA DBX2 ; Xenbase dbx2    NEW 
Molecular
reagents
All nucleic(12) Genomic(1) cDNA(6) Primer pair(2) Other(3)
Microarray probesets(1)
Other database
links
VEGA Gene Model OTTMUSG00000037232 (Evidence)
Ensembl Gene Model ENSMUSG00000045608 (Evidence)
Entrez Gene 223843 (Evidence)
UniGene 152937
DFCI TC1648725, TC1588785
DoTS DT.101718665, DT.91382860
NIA Mouse Gene Index U036581
Consensus CDS Project CCDS37183.1
International Mouse Phenotyping Consortium Status Dbx2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000037232 VEGA Gene Model | MGI Sequence Detail 32398 C57BL/6J ±  kb
transcript OTTMUST00000096005 VEGA | MGI Sequence Detail 3460 Not Applicable 
polypeptide OTTMUSP00000053595 VEGA | MGI Sequence Detail 377 Not Applicable 

For the selected sequences
All sequences(22) RefSeq(2) UniProt(2)
Polymorphisms
SNPs within 2kb(281 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR000047 Helix-turn-helix motif
InterPro IPR017970 Homeobox, conserved site
InterPro IPR001356 Homeodomain
InterPro IPR009057 Homeodomain-like
InterPro IPR020479 Homeodomain, metazoa
Protein Ontology PR:000006302 homeobox protein DBX2
References
(Earliest) J:33698 Shoji H, et al., Regionalized expression of the Dbx family homeobox genes in the embryonic CNS of the mouse. Mech Dev. 1996 May;56(1-2):25-39
(Latest) J:207050 Zhao X, et al., Dynamic expression of secreted Frizzled-related protein 3 (sFRP3) in the developing mouse spinal cord and dorsal root ganglia. Neuroscience. 2013 Jul 1;248C:594-601
All references(48)
Other
accession IDs
MGD-MRK-35916, MGI:2146074, MGI:2686075

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
06/23/2015
MGI 5.22
The Jackson Laboratory