About   Help   FAQ
Elavl4
Gene Detail
 Symbol
Name
ID
Elavl4
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
MGI:107427
Synonyms Hud
Feature Type protein coding gene
Genetic Map
Chromosome 4
51.42 cM
Detailed Genetic Map ± 1 cM


Mapping data(4)
Sequence Map
Chr4:110203722-110351909 bp, - strand
From VEGA annotation of GRCm38

  148188 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:40729  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Elavl4

Human
homologs
Human Homolog ELAVL4, ELAV like neuron-specific RNA binding protein 4
NCBI Gene ID 1996
neXtProt AC  NX_P26378
Human Synonyms  HUD, PNEM
Human Chr (Location)  1p34; chr1:50048014-50203770 (+)  GRCh38
Alleles
and
phenotypes
All alleles(9) : Gene trapped(8) Targeted(1)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a null allele display increased neural progenitor self-renewal and impaired neuronal differentiation, partial penetrance of hind limb clasping, and impaired coordination.
 
Gene Ontology
(GO)
classifications
All GO classifications: (5 annotations)
Function AU-rich element binding, nucleic acid binding, ...
External Resources: FuncBase
Expression
Literature Summary: (81 records)
Data Summary: Results (113)    Tissues (83)    Images (30)
Theiler Stages: 15, 19, 20, 21, 22, 23, 24, 26, 28
Assay TypeResults
Immunohistochemistry 6
RNA in situ 90
Northern blot 9
Western blot 6
RT-PCR 2
cDNA source data(50)
External Resources: GENSAT   GEO   ArrayExpress
Molecular
reagents
All nucleic(59) Genomic(6) cDNA(51) Primer pair(2)
Microarray probesets(6)
Other database
links
VEGA Gene ModelOTTMUSG00000008498 (Evidence)
Ensembl Gene ModelENSMUSG00000028546 (Evidence)
Entrez Gene15572 (Evidence)
UniGene3970
DFCITC1581125, TC1585096, TC1590771, TC1594391, TC1604984, TC1777616
DoTSDT.101296979, DT.101372349, DT.103564930, DT.110806712, DT.60104286, DT.94334331, DT.97406086, DT.99856857
NIA Mouse Gene IndexU025377
Consensus CDS ProjectCCDS18470.1, CCDS18471.1, CCDS51261.1, CCDS51262.1
International Mouse Knockout Project StatusElavl4
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000008498 VEGA Gene Model | MGI Sequence Detail 148188 C57BL/6J ±  kb
transcript OTTMUST00000019294 VEGA | MGI Sequence Detail 4149 Not Applicable 
polypeptide OTTMUSP00000008853 VEGA | MGI Sequence Detail 385 Not Applicable 

For the selected sequences
All sequences(124) RefSeq(30) UniProt(15)
Polymorphisms All PCR and RFLP(3) : PCR(1) RFLP(2) SNPs within 2kb(1046 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR012677 Nucleotide-binding, alpha-beta plait
InterPro IPR002343 Paraneoplastic encephalomyelitis antigen
InterPro IPR000504 RNA recognition motif domain
InterPro IPR006548 Splicing factor ELAV/HuD
Protein Ontology PR:000007019 ELAV-like protein 4
References (Earliest) J:31495 Abe R, et al., Tissue-specific expression of the gene encoding a mouse RNA binding protein homologous to human HuD antigen. DNA Res. 1994;1(4):175-80
(Latest) J:209618 DeBoer EM, et al., Prenatal deletion of the RNA-binding protein HuD disrupts postnatal cortical circuit maturation and behavior. J Neurosci. 2014 Mar 5;34(10):3674-86
All references(121)
Other
accession IDs
MGD-MRK-35898

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
07/15/2014
MGI 5.18
The Jackson Laboratory